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ANTI-TUBERCULOSIS: 作品数：38被引量：136H指数：6; 导出分析报告; 相关作者：王婉更多>>; 相关机构：安徽理工大学更多>>; 相关期刊：《Chinese Journal of Integrative Medicine》《Open Journal of Medical Microbiology》《Journal of Tuberculosis Research》《World Journal of Gastroenterology》更多>>; 相关基金：国家自然科学基金国家高技术研究发展计划中国博士后科学基金国家重点基础研究发展计划更多>>

Asperochones A and B,two antimicrobial aromatic polyketides from the endophytic fungus Aspergillus sp.MMC-2: 《Chinese Chemical Letters》2024年第9期206-209,共4页Hong Zhang Cui-Ping Li Li-Li Wang Zhuo-Da Zhou Wen-Sen Li Ling-Yi Kong Ming-Hua Yang; supported by the National Natural Science Foundation of China(No.32170403);the 111 Center from Ministry of Education of China and the State Administration of Foreign Experts Affairs of China(No.B18056);the“Double First-Class”University Project(No.CPU2018GF03);the Drug Innovation Major Project(Nos.2018ZX09711-001-007 and 2018ZX09735002-003)。; Two novel fungal metabolites,asperochones A and B,were obtained from an Aspergillus sp.Their structures were determined by 1D/2D nuclear magnetic resonance(NMR)spectroscopy,high resolution electrospray ionization mass...; 关键词：Aspergillus sp. Asperochones A and B Aromatic polyketides Heterotrimeric compound Anti-tuberculosis effect Antifibrotic activity

Effects of Yigan Capsule on the expression of HMGB1,RAGE and NF-κB protein in rats with drug-induced liver injury: 《Journal of Hainan Medical University》2024年第4期8-14,共7页TANG Ya LI Jun QI Yazhi CAO Rui ZHAI Yan-ling HAN Yu-sheng XU Qiang; Scientific Research Project of Heilongjiang Provincial Education Department(No.12531608)。; Objective:To study the effect of Yigan capsule on the expression of high mobility group protein B1(HMGB1),nuclear factor-B(NF-κB)and receptor for advanced glycation end products(RAGE)in anti-tuberculosis drug-induced...; 关键词：Yigan capsule Anti-tuberculosis drug-induced liver INJURY HMGB1 RAGE NF-κB

Push forward LC-MS-based therapeutic drug monitoring and pharmacometabolomics for anti-tuberculosis precision dosing and comprehensive clinical management被引量：1: 《Journal of Pharmaceutical Analysis》2024年第1期16-38,共23页Nguyen Quang Thu Nguyen Tran Nam Tien Nguyen Thi Hai Yen Thuc-Huy Duong Nguyen Phuoc Long Huy Truong Nguyen; sponsored by the National Research Foundation of Korea(NRF)Grant funded by the Korean government(MSIT)(Grant No.:2018R1A5A2021242).; The spread of tuberculosis(TB),especially multidrug-resistant TB and extensively drug-resistant TB,has strongly motivated the research and development of new anti-TB drugs.New strategies to facilitate drug combination...; 关键词：TUBERCULOSIS Therapeutic drug monitoring LC-MS MIPD Pharmacometabolomics Precision medicine

Asymmetric Synthesis of Anti-tuberculosis-specific Drug TBAJ-876 through Synergistic Li/Li Catalysis被引量：1: 《Chinese Journal of Chemistry》2023年第11期1319-1326,共8页Jing Li Feng Gao Tanveer Ahmad Yicong Luo Zhenfeng Zhang Qianjia Yuan Wanbin Zhang; funding support of this work by the Bill and Melinda Gates Foundation(No.INV-008413);the National Natural Science Foundation of China(No.21831005)and Shanghai Jiao Tong University.; TBAJ-876, developed by TB Alliance, a novel anti-tuberculosis-specific drug, has entered Phase II clinical trials. Herein, the first asymmetric synthesis of TBAJ-876 has been realized using synergistic Li/Li catalysis...; 关键词：Asymmetric synthesis TBAJ-876 Synergistic Li Li catalysis DFT calculations Noncovalent interactions Coordination modes LITHIUM ENANTIOSELECTIVITY

Time of Liver Function Abnormal Identification on Prediction of the Risk of Anti-tuberculosis-induced Liver Injury: 《Journal of Clinical and Translational Hepatology》2023年第2期425-432,共8页Deliang Huang Jinghan Peng Lin Lei Yuanyuan Chen Zhibing Zhu Qingxian Cai Yongcong Deng Jun Chen; supported by the funds for the construction of key medical disciplines in Shenzhen.; Background and Aims:Anti-tuberculosis(anti-TB)druginduced liver injury(AT-DILI)is the most common side effect in patients who received anti-TB therapy.AT-DILI management includes monitoring liver function until sympto...; 关键词：Liver function abnormal identification time Anti-tuberculosis induced liver injury Liver failure RUCAM causality scale

Discovery of natural-product-derived sequanamycins as potent oral anti-tuberculosis agents: 《四川生理科学杂志》2023年第2期230-230,共1页Jidong Zhang; The emergence of drug-resistant tuberculosis has created an urgent need for new anti-tubercular agents. Here, we report thediscovery of a series of macrolides called sequanamycins with outstanding in vitro and in vivo...; 关键词：TUBERCULOSIS DRUGS OVERCOME

SARS-COV-2 Infection and Anti-Tuberculosis Immunity: Temporal Association or Real Protective Role?: 《Advances in Infectious Diseases》2022年第4期656-667,共12页Sanaa Hammi Myriem Bourkia Adil Najdi Rajae Chahboune Karima Rissoul Jamal Eddine Bourkadi Jouda Benamor Fatema El Bouzouiki Soumiya El Bachiri Mohammed Moumkin Rachid Ismaili Nadira Mourabait Ouafae Kaissi Asmae Zerrouki Adil Grourinda Fadila Bousgheiri Hassana Belafki Mhamed Harif Mohamed Ahalat; Introduction: According to the literature consulted to date, there is epidemiological heterogeneity of Covid-19 between countries depending on their vaccination policy, in particular BCG vaccination. These findings ha...; 关键词：BCG Nonspecific Anti-Tuberculosis Immunity Covid-19

Solitary splenic tuberculosis:A case report被引量：1: 《World Journal of Clinical Cases》2022年第28期10260-10265,共6页Hong-Wei Guo Xiu-Qing Liu Yan-Li Cheng; BACKGROUND Solitary splenic tuberculosis(TB) is unusual and rarely reported.Whether splenic TB is best treated surgically is still controversial.We describe a 73-year-old man with solitary splenic TB and no extrapulmo...; 关键词：Infectious diseases Solitary splenic tuberculosis Computed tomography Computed tomography-guided spleen biopsy Anti-tuberculosis medicine Pathological diagnosis Case report

Study on the Clinical Effect of Pulmonary Tuberculosis Combined with Anti-tuberculosis Regimen and Levofloxacin: 《外文科技期刊数据库(文摘版)医药卫生》2022年第5期195-198,共4页LIZechen WANGTao; The efficacy of levofloxacin combined with traditional anti-tuberculosis drugs was compared between the two groups. Methods: The trial was conducted between January 2021 and March 2022 and included a total of 78 patie...; 关键词：pulmonary tuberculosis anti-tuberculosis regimen LEVOFLOXACIN EFFICACY

Observation on the Effect of Anti-tuberculosis Plate Combination Drug in the Treatment of Pulmonary Tuberculosis: 《外文科技期刊数据库(文摘版)医药卫生》2022年第7期174-178,共5页YUDongqin; Objective: to analyze the effect of anti tuberculosis plate combination drugs in the treatment of pulmonary tuberculosis. Methods: 62 patients with pulmonary tuberculosis (March November 2021) were randomly selected a...; 关键词：anti-tuberculosis plate-type combination drug TUBERCULOSIS sputum negative conversion rate incidence of adverse reactions effective rate of lesion absorption lung function index

ANTI-TUBERCULOSIS