NUCLEUS

作品数：813被引量：803H指数：11
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相关机构：华中科技大学重庆邮电大学中国科学院解放军信息工程大学更多>>
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circFKBP8(5S,6)-encoded protein as a novel endogenous regulator in major depressive disorder by inhibiting glucocorticoid receptor nucleus translocation
《Science Bulletin》2024年第24期3826-3831,共6页Jiao Jiao Dandan Xu Yan Kong Yujia Cao Liyuan Wang Yuan Hong Ling Li Chenyu Gao Jing Liu Gaojia Zhang Jiangning Zhou Ji Dai Zhonghua Lu Yan Liu Yutian Wang Zhijun Zhang 
supported by the Chinese Science and Technology Innovation 2030-Major Project(2022ZD0211701 and 2021ZD0200700);the National Natural Science Foundation of China(82130042,81830040 and 82371532);Shenzhen Science and Technology Serial Funds(GJHZ20210705141400002,KCXFZ20211020164543006,JCYJ20220818101615033,ZDSYS202-20606100606014,and KQTD20221101093608028).
Major depressive disorder(MDD)is a debilitating mental health condition that ranks second in the global burden of human diseases[1].Despite extensive research,the etiology and pathogenesis of MDD remain poorly underst...
关键词：GLUCOCORTICOID ENDOGENOUS INHIBITING 
Regulation of canonical Wnt/β-catenin pathway in the nucleus
《Chinese Science Bulletin》2014年第28期3530-3535,共6页Wenxiao Han Hongying Wang 
supported by the National Nature Science Foundation of China(81172034)
Canonical Wnt/b-catenin pathway plays a central role in development, homeostasis, as well as tumorigenesis. The regulation of the pathway involves various and complicated mechanisms, including the extracellular, intra...
关键词：细胞核 WNT 蛋白复合物 法规 肿瘤发生 组成部分 监管机构 转录活性 
Transfer of a eubacteria-type cell division site-determining factor CrMinD gene to the nucleus from the chloroplast genome in Chlamydomonas reinhardtii
《Chinese Science Bulletin》2007年第18期2514-2521,共8页LIU WeiZhong HU Yong ZHANG RunJie ZHOU WeiWei ZHU JiaYing LIU XiangLin HE YiKun 
Supported by the National Natural Science Foundation of China (Grant Nos. 30500288 and 30470879) ;the Natural Science Foundation of Beijing (Grant No. 5032003)
MinD is a ubiquitous ATPase that plays a crucial role in selection of the division site in eubacteria, chloroplasts, and probably Archaea. In four green algae, Mesostigma viride, Nephroselmis olivacea, Chlorella vulga...
关键词：衣藻 叶绿体 CrMinD基因 基因转移 植物进化 
Protein synthesis inhibition in the basolateral nucleus of amygdala facilitates extinction of auditory fear memory
《Chinese Science Bulletin》2007年第18期2532-2542,共11页JIN XinChun QI XueLian YANG XiaoFei LI BaoMing 
Supported by grants to Bao-Ming Li from the Ministry of Science and Technology of China (Grant No. 2006CB500807);the Ministry of Education of China (Program for Changjiang Scholars and Innovative Research Team in University);the National Natural Science Foundation of China (Grant Nos. 30225023, 30430240 and 30611120530)
It is known that consolidation of fear conditioning requires de novo protein synthesis in the amygdala. However, there is controversy about the role of protein synthesis in post-retrieval extinction of fear memory. Th...
关键词：蛋白质合成 扁桃体 听觉 衰退 
INFLUENCE OF ATMOSPHERIC ICE NUCLEUS CONCENTRATIONS ON COLD CLOUD RADIANT PROPERTIES AND COLD CLOUD REFLECTIVITY CHANGES IN PAST YEARS被引量：5
《Chinese Science Bulletin》2006年第4期480-489,共10页LI Juan MAO Jietai 
PAL satellite dataset which have long temporal span is used in the study. Relationship be-tween cold cloud reflectivity and aerosol concentra-tion in Beijing is analyzed as an example. From analysis, cold cloud reflec...
关键词：大气科学 云 冰核 反射率改变 
β-Adrenergic activation enhances NMDA-induced current in pyramidal cells of the basolateral nucleus of amygdala
《Chinese Science Bulletin》2005年第17期1966-1968,共3页LIU Xinqiu CAO Xiaohua LI Bao-ming 
This work was supported by the Ministry of Sci-ence and Technology of China(Grant No.2006CB 500807);the National Natural Science Foundation of China(Grant Nos.30225023&30430240);the Shanghai Metropolitan Key Basic Research Program(Grant No.04DZ14005).
NMDA receptor (NMDA-R) in the amygdala complex is critical for both long-term potentiation (LTP) and formation of conditioned fear memory. It is reported that activation of β-adrenoceptors (β-AR) in the amygdala fac...
关键词：β-肾上腺素 NMDA 受体 扁桃体 记忆体 
Production of transgenic blastocyst of sheep by somatic cell cloning被引量：13
《Chinese Science Bulletin》2001年第19期1630-1634,1674,共6页Xiaorong An Kemian Gou Yongfu Chen 
This work was supported by the National "863" Project (Grant No. Z21-01- 01).
Five samples from primary cultures of five sheep ovarian granulosa cells were transfected by pEGFP-N1 DNA. Five transgenic positive cell lines, each from one of the five samples above, were used as donor nuclei for so...
关键词：SHEEP GRANULOSA cell NUCLEUS TRANSFER TRANSGENIC blastocyst. 
Temporal properties of pattern adaptation of relay cells in the lateral geniculate nucleus of cats被引量：2
《Chinese Science Bulletin》2001年第17期1463-1465,共3页YANG Yupeng JIN Jianzhong ZHOU Yifeng SHOU Tiande 
the National NaturalScience Foundation of China (Grant Nos. 97908003 and 30070257); the Foundation of the Chinese Academy of Sciences (Grant No. 39893340-03).
The temporal properties of pattern adaptation of relay cells induced by repeated sinusoidal drifting grating were investigated in the dorsal lateral geniculate nucleus (dLGN) of cats. The results showed that the respo...
关键词：PATTERN ADAPTATION TEMPORAL properties LATENCY phase lateral geniculate NUCLEUS cat. 
Inhibiting pain with pain——A basic neuromechanism of acupuncture analgesia
《Chinese Science Bulletin》2001年第17期1485-1494,共10页LIU XiangInstitute of Acupuncture and Moxibustion, China Academy of Traditional Chinese Medicine, Beijing 100700, China 
(i) The structure and function of the meridian (channel and collateral) described by ancient medical doctors may correspond to the blood circulation, nerve control and neurohumoral modulation of modern medicine. (ii) ...
关键词：acupuncture ANALGESIA INHIBITING PAIN with PAIN negative feedback mechanism of PAIN NUCLEUS RAPHE magnus AFFERENT C fiber capsaicm. 
The recognizing of ca. 1.95 Ga tectono-thermal eventin Kong-ling nucleus and its significance for the evolution of Yangtze Block, South China被引量：30
《Chinese Science Bulletin》2001年第4期326-329,共4页LING Wenli GAO Shan ZHANG Benren ZHOU Lian XU Qidong 
the National Natural Science Foundation of China (Grant Nos. 49603044, 49625305, 49873010 and 49794043) ; the Project of the Open Laboratory of Consitution, Interaction and Dynamics of Crust-Mantle System, the Ministry of Land and Resources of China.
Some 1.95 Ga metamorphism of high-grade Ar-chean rocks in Kongling terrain, continental nucleus of Yangtze Block, South China, are recognized by Sm-Nd dating. This event is further confirmed by the ages of single zirc...
关键词：Kongling HIGH-GRADE METAMORPHIC terrain tectono-thermal event PALEOPROTEROZOIC unitive basement. 
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