SPHINGOLIPID

作品数:26被引量:50H指数:4
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相关领域:医药卫生生物学更多>>
相关作者:陈光英朱峰林永成袁震于红梅更多>>
相关机构:佛山科学技术学院中山大学海南师范大学第四军医大学更多>>
相关期刊:《Molecular Plant》《International Journal of Oral Science》《Journal of Integrative Plant Biology》《肝胆胰外科杂志》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
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Proteomic analysis revealed the function of PoElp3 in development,pathogenicity,and autophagy through the tRNA-mediated translation efficiency in the rice blast fungus
《Journal of Integrative Agriculture》2025年第4期1515-1528,共14页Yuanhao Liu Ting Sun Yuyong Li Jianqiang Huang Xianjun Wang Huimin Bai Jiayi Hu Zifan Zhang Shuai Wang Dongmei Zhang Xiuxiu Li Zonghua Wang Huakun Zheng Guifang Lin 
supported by National Natural Science Foundation of China(32172365 and 32272513);the Central Guidance on Local Science and Technology Development Fund of Fujian Province,China(2022L3088);the Innovative Research Funding of Fujian Agriculture and Forestry University,China(CXZX2020153D)。
The Elongator complex is conserved in a wide range of species and plays crucial roles in diverse cellular processes.We have previously shown that the Elongator protein PoElp3 was involved in the asexual development,pa...
关键词:Elongator TRNA proteomics translational efficiency sphingolipid C9-methyltransferase rice blast fungus 
A sphingolipid message promotes neuronal health across generations
《Neural Regeneration Research》2024年第11期2325-2326,共2页Wenyue Wang Roger Pocock 
supported by the National Health and Medical Research Council grants GNT1105374,GNT1137645 and GNT2000766(to RP).
Maternal nutrition can affect brain function of offspring in later life(Fitzgerald et al.,2020).Emerging studies have also shown that the maternal environment can modify susceptibility to neurodegenerative disease(Boo...
关键词:MOTHER INTESTINE TRANSFERRED 
Sphingolipid inhibitor response gene GhMYB86 controls fiber elongation by regulating microtubule arrangement
《Journal of Integrative Plant Biology》2024年第9期1898-1914,共17页Fan Xu Guiming Li Shengyang He Zhifeng Zeng Qiaoling Wang Hongju Zhang Xingying Yan Yulin Hu Huidan Tian Ming Luo 
funded by the National Natural Science Foundation of China(31571722 and 31971984);the Genetically Modified Organisms Breeding Major Project of China(No.2018ZX0800921B);Fundamental Research Funds for the Central Universities(SWU‐XDJH202315).
Although the cell membrane and cytoskeleton play essential roles in cellular morphogenesis,the interaction between the membrane and cytoskeleton is poorly understood.Cotton fibers are extremely elongated single cells,...
关键词:cotton fiber membrane sphingolipid microtubule arrangement 
α1-COP modulates plasmodesmata function through sphingolipid enzyme regulation
《Journal of Integrative Plant Biology》2024年第8期1639-1657,共19页Arya Bagus Boedi Iswanto Minh Huy Vu Jong Cheol Shon Ritesh Kumar Shuwei Wu Hobin Kang Da-Ran Kim Geon Hui Son Woe Yoen Kim Youn-Sig Kwak Kwang Hyeon Liu Sang Hee Kim Jae-Yean Kim 
supported by the National Research Foundation of Korea(NRF)grant funded by the Korea Government(MSIT)(Grant Nos.NRF 2018R1A2A1A05077295,2020M3A9I4038352,2022R1A2C3010331,2020R1A6A1A03044344,and 2022R1A 5A1031361);a grant from the New Breeding Technologies Development Program(Grant No.PJ01653202),Rural Development Administration(RDA),Republic of Korea。
Callose,aβ-1,3-glucan plant cell wall polymer,regulates symplasmic channel size at plasmodesmata(PD)and plays a crucial role in a variety of plant processes.However,elucidating the molecular mechanism of PD callose h...
关键词:CALLOSE coatomer proteins membrane-bound vesicle PLASMODESMATA sphingolipid enzymes 
Characterization of the sphingolipid profiling of Emiliania huxleyi against virus infection
《Journal of Oceanology and Limnology》2023年第4期1547-1557,共11页Jingwen LIU Jingjing GAO Enquan ZHANG Hanrui JIANG Guiling LI Jian LI Jun ZENG Daren WU 
Supported by the National Natural Science Foundation of China(Nos.42076086,41576166);the Natural Science Foundation of Fujian Province(No.2020J05138);the Education and Research Project for Young and Middle-aged Teachers of Fujian Province(No.JAT190343);the Cultivation Plan for Distinguished Young Scholars in Fujian Universities。
Lipidomics approach by UPLC-Q-Exactive-MS was used for the identification,quantification,comparison,and characterization of sphingolipids in virus infected marine Emiliania huxleyi BOF92 cells.The results show that 16...
关键词:Emiliania huxleyi Coccolithovirus UPLC-Q-Exactive-MS sphingolipid metabolism biomarkers 
miR-139-5p对人肝癌细胞增殖和侵袭的影响
《肝胆胰外科杂志》2023年第3期156-163,共8页袁震 杨晓娣 于红梅 叶涛 
上海市闵行区科委项目(2021MHZ100)。
目的 探讨微小RNA(miRNA)-139-5p在肝癌组织中的表达及其对人肝癌细胞增殖、侵袭的影响和潜在的分子机制。方法 采用生物信息学方法,从GEO数据库中下载GSE36915数据集,进行差异miRNA分析,结合TCGA-LICH数据集中的生存数据,筛选与预后显...
关键词:肝细胞癌 miR-139-5p Sphingolipid信号通路 神经酰胺合成酶6(CerS6) 
Role of glioma immune biomarker ORMDL2 in the diagnosis and prognosis of glioma
《Journal of Hainan Medical University》2023年第6期28-36,共9页YAN Dong-ming LIANG Jian-tang LIU Xiao-qian LI Meng-yongwei DING Shun MENG Qing-wen ZHANG Si-yuan TANG Cai-ying LIU Qi-bing YANG Kun 
Finance Science and Technology Project of Hainan Province(ZDYF2022SHFZ088),Hainan Medical University Postgraduate Innovative Research Project Category B(HYYS2021B16)。
Obiective:To investigate the prognostic value of ORMDL2 in human glioma and its relationship with immune invasion.Methods:The clinical survival data from TCGA-LGG&GBM,CGGA and GEO were used to evaluate the clinical pr...
关键词:GLIOMA ORMDL2 SPHINGOLIPID Immune infiltration BIOMARKER 
Erythrocyte sphingolipid species as biomarkers of Alzheimer's disease被引量:4
《Journal of Pharmaceutical Analysis》2022年第1期178-185,共8页Jericha Mill Vihar Patel Ozioma Okonkwo Lingjun Li Thomas Raife 
supported in part by the National Institutes of Health(NIH)(Grant No.:RF1AG052324);a predoctoral traineeship supported by the NIH T32 training grant on Biology of Aging and Age-related Diseases(Grant No.:T32AG000213);funding provided by the Wisconsin Alumni Research Foundation;School of Pharmacy,University of Wisconsin-Madison
Diagnosing Alzheimer’s disease(AD)in the early stage is challenging.Informative biomarkers can be of great value for population-based screening.Metabolomics studies have been used to find potential biomarkers,but com...
关键词:Alzheimer’s disease Neurodegenerative disease Mass spectrometry Erythrocytes Biomarkers Metabolomics 
Phytosphinganine Affects Plasmodesmata Permeability via Facilitating PDLP5-Stimulated Callose Accumulation in Arabidopsis被引量:6
《Molecular Plant》2020年第1期128-143,共16页Ning-Jing Liu Tao Zhang Zhao-Hui Liu Xin Chen Hui-Shan Guo Bai-Hang Ju Yuan-Yuan Zhang Guo-Zhu Li Qiang-Hui Zhou Yong-Mei Qin Yu-Xian Zhu 
This research was supported by grants from the National Science and Technology Major Project(2016ZX08010-001);the National Natural Science Foundation of China(31570283).
Plant plasmodesmata (PDs) are specialized channels that enable communication between neighboring cells. The intercellular permeability of PDs, which affects plant development, defense, and responses to stimuli, must b...
关键词:PLASMODESMATA phytosphinganine SPHINGOLIPID binding MOTIF PDLP5 
Emerging roles of sphingosylphosphorylcholine in modulating cardiovascular functions and diseases被引量:1
《Acta Pharmacologica Sinica》2018年第12期1830-1836,共7页Di Ge Hong-wei Yue Hong-hong Liu Jing Zhao 
Sphingosylphosphorylcholine (SPC) is a bioactive sphingolipid in blood plasma that is metabolized from the hydrolysis of the membrane sphingolipid. SPC maintains low levels in the circulation under normal conditions, ...
关键词:SPHINGOSYLPHOSPHORYLCHOLINE SPHINGOLIPID second MESSENGER first MESSENGER G protein-coupled receptor membrane lipid raft MYOCYTES VEIN endothelial cell vascular smooth muscle cells 
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