supported by the grants from the National Key R&D Program of China(Nos.2022YFA1303301 and 2021YFA1100201);the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB0570000);the National Natural Science Foundation of China(Nos.31970607 and 31470781 to L.W.,No.32200696 to H.Z.);the China Postdoctoral Science Foundation(No.2021M700146 to H.Z.);the Heye Scholarship(to X.L.).
PIWI-interacting RNAs(piRNAs),which associate with PIWI clade Argonaute proteins to form piRNA-induced silencing complexes(piRISCs)in germline cells,are responsible for maintaining genomic integrity and reproductive f...