TERBINAFINE

作品数：16被引量：34H指数：3
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相关领域：医药卫生更多>>
相关作者：林谋斌吴绍熙周华周明莉吕成斌更多>>
相关机构：中国科学院大学台北医学大学复旦大学同济大学更多>>
相关期刊：《Chinese Medical Journal》《Precision Clinical Medicine》《Journal of Biosciences and Medicines》《药学进展》更多>>
相关基金：上海市自然科学基金国家自然科学基金更多>>
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Depletion of squalene epoxidase in synergy with glutathione peroxidase 4 inhibitor RSL3 overcomes oxidative stress resistance in lung squamous cell carcinoma
《Precision Clinical Medicine》2024年第2期109-121,共13页Guo Li Lu Chen Hua Bai Li Zhang Jie Wang Weimin Li 
the National Natural Science Foundation of China(Grant No.92159302,W.L.);Science and Technology Project of Sichuan(Grant No.2022ZDZX0018,W.L.);1.3.5 project for disciplines of excellence,West China Hospital,Sichuan University(Grant No.ZYGD22009,W.L.);National Key R&D program of China(Grant No.2022YFC2505000);NSFC general program(Grant No.82272796);NSFC special program(Grant No.82241229);CAMS Innovation Fund for Medical Sciences(Grant No.CIFMS 2022-I2M-1-009);CAMS Key Laboratory of Translational Research on Lung Cancer(Grant No.2018PT31035);the Aiyou foundation(Grant No.KY201701).
Background:Lung squamous cell carcinoma(Lusc)lacks effective targeted therapies and has a poor prognosis.Disruption of squalene epoxidase(SQLE)has been implicated in metabolic disorders and cancer.However,the role of ...
关键词：lung squamous cell carcinoma squalene epoxidase TERBINAFINE ROS ferroptosis 
Quality assurance of postharvest grapes against Botrytis cinerea by terbinafine
《Natural Products and Bioprospecting》2023年第1期502-513,共12页Yun Zhao Qiong Jin Zi-Jiao Wang Xing-Yu Tao Xiao-Dong Luo 
the High-level Talent Promotion and Training Project of Kunming(2022SCP003);Project of Yunnan Characteristic Plant Screening and R&D Service CXO Platform(2022YKZY001);Scientific and Technological Innovation Team of Yunnan Province(202105AE160006)financial support。
Worldwide,fruit is an indispensable treasure house of nutrition for human beings,occupying a vital position of human diet.Postharvest fruit storage requires efficient antifungal agents to control Botrytis cinerea,whic...
关键词：TERBINAFINE Botrytis cinerea Antifungal activity Cell membrane Grape preservation 
角鲨烯环氧酶通过积累骨化三醇和激活CYP24A1介导的MAPK信号通路促进结直肠癌细胞增殖被引量：3
《癌症》2022年第11期509-529,共21页何璐薇 李华光 潘晨宇 华雨桐 彭甲银 周兆才 赵允 林谋斌 
国家自然科学基金(No.31630047、No.81874201、No.81725014);上海市自然科学基金(No.20ZR1452300);上海市卫生局(No.201840359);国家重点研发计划(No.2020YFA0509000和No.2017YFA0503600)的支持。
背景与目的结直肠癌(colorectal cancer,CRC)是一种高发的恶性肿瘤,其分子机制和靶向治疗有待进一步研究。代谢紊乱是癌症的重要特征。靶向调节肿瘤代谢途径已成为现代肿瘤治疗的重要方向。在本研究中,我们旨在研究一种新的促进CRC增殖...
关键词：骨化三醇 细胞增殖 胆固醇生物合成 结直肠癌 CYP24A1 MAPK信号通路 鲨烯环氧酶 TERBINAFINE 
Fungal Translocation Marker in People Living with HIV Needing Treatment for Onychomycosis: A Protocol for the Prospective Pilot Study
《Infectious Diseases & Immunity》2022年第2期122-124,共3页Yaling Chen Jing Ouyang Stéphane Isnard Cecilia T.Costiniuk Jiangyu Yan Xin Zhou Jean-Pierre Routy Yaokai Chen 
This work was supported by the Joint Medical Research Project(2020GDRC010)of Chongqing Science&Technology Bureau and Chongqing Health Commission,the Research Project of Chinese Federation of Public Health foundation(GWLM202024);the Youth Scientific Research and Innovation Fund Project of Chongqing Public Health Medical Center(2019QNKYXM02).
Increased microbial translocation and chronic immune activation are two critical problems for people living with HIV(PLWH)in the antiretroviral therapy(ART)era.Compared with numerous studies on bacterial microbiomic c...
关键词：HIV Fungal translocation Microbial translocation ONYCHOMYCOSIS TERBINAFINE 
Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1-mediatedMAPK signaling被引量：9
《Cancer Communications》2021年第8期726-746,共21页Luwei He Huaguang Li Chenyu Pan Yutong Hua Jiayin Peng Zhaocai Zhou Yun Zhao Moubin Lin 
National Natural Science Foundation of China,Grant/Award Numbers:31630047,81874201,81725014;Natural Science Foundation of Shanghai,Grant/AwardNumber:20ZR1452300;Shanghai Municipal Health Bureau,Grant/Award Number:201840359;The National Key Research and Development Program of China,Grant/Award Numbers:2020YFA0509000,2017YFA0503600。
Background:Colorectal cancer(CRC)is one of the most malignant tumorswith high incidence,yet its molecular mechanism is not fully understood,hindering the development of targeted therapy.Metabolic abnormalities are a h...
关键词：CALCITRIOL cell proliferation cholesterol biosynthesis colorectal cancer CYP24A1 MAPK signaling squalene epoxidase TERBINAFINE 
Evaluation of the Permeation and Penetration of Two Formulations of Terbinafine Chlorhydrate Incorporated in Liposomes (Cream 1%) vs. a Conventional Formulation (Cream 1%), in an <i>in Vitro-ex Vivo</i>Model
《Journal of Biosciences and Medicines》2019年第8期119-133,共15页Sanabria Kinski Annunziato Maria Antonieta Chacon Nicolas Inatti Alfredo 
In this trial, a topical formulation of a 1% liposome TH cream was compared to a conventional TH formulation. Permeation was evaluated through a synthetic membrane. The study provided information on the rate of diffus...
关键词：ANTIFUNGAL Franz Diffusion Cell Tape Striping Method Liposome TERBINAFINE HCl Drug Carrier Systems STRATUM Corneum 
<i>Rhizopus oryzae</i>Retro-Orbital Abscess: Comparison of Spores and Hyphae Antifungal Susceptibility and Clinical Outcome
《Open Journal of Medical Microbiology》2018年第1期1-11,共11页Adenilza Cristina S. Fonseca Ana Beatriz A. Teixeira-Loyola Luzia Lyra Ariane F. Busso Yasunori Muraosa Hideaki Taguchi Maria Luiza Moretti Angélica Z. Schreiber 
Rhizopus is fungus of the order Mucorales, responsible for invasive diseases called mucormycosis. The correct identification of these fungi is one of the main questions raised in the literature since the diagnosis is ...
关键词：Antifungal Susceptibility Testing MUCORALES TERBINAFINE AMPHOTERICIN B ITRACONAZOLE 
疑似Terbinafine导致急性肝伤害：案例报告
《臺灣臨床藥學雜誌》邵時傑(Shih-Chieh Shao) 高淑敏(Shu-Min Kao) 高雅慧(Yea-Huei Kao) 張定宗(Ting-Tsung Chang) 
Terbinafine为抗霉菌药物，临床上此药导致的肝伤害属罕见（约0.1%）之不良反应。目前认为的致病机转可能包括：terbinafine或其代谢物直接对肝细胞产生毒性、terbinafine诱发之免疫反应及基因多型性等因素所造成。过去案例报告中，病...
关键词：療黴舒 藥物肝傷害 急性肝傷害 肝炎 
Isolated ileal perforation due to cytomegalovirus reactivation during management of terbinafine hypersensitivity被引量：2
《World Journal of Gastroenterology》2010年第26期3339-3342,共4页Soichi Sano Hiroki Ueno Keiko Yamagami Yosuke Yakushiji Yoshihiro Isaka Isao Kawasaki Masashi Takemura Takeshi Inoue Masayuki Hosoi 
We report a case of 71-year-old man who developed a hypersensitivity syndrome associated with terbinafine. He was placed on terbinafine (250 mg/d) for the treatment of tinea pedis due to diabetes mellitus. Following t...
关键词：Terbinafi ne Drug hypersensitivity Human herpesvirus 6 CYTOMEGALOVIRUS Intestinal perforation ILEUM 
Effect of topical application of terbinafine on fungal keratitis被引量：8
《Chinese Medical Journal》2009年第16期1884-1888,共5页LIANG Qing-feng JIN Xiu-ying WANG Xiang-lan SUN Xu-guang 
Background Fungal keratitis is a rare but serious corneal disease that may result in loss of vision. The poor prognosis might be due to limited treatment option. This study aimed to evaluate the clinical efficacy of 0...
关键词：TERBINAFINE NATAMYCIN KERATITIS FUNGAL THERAPY 
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