云南高校图书馆联盟文献共享服务平台- Α-HELIX

Α-HELIX: 作品数：17被引量：22H指数：3; 导出分析报告; 相关领域：生物学更多>>; 相关作者：秦红珊王克起杨新岐更多>>; 相关机构：天津大学更多>>; 相关期刊：《Acta Pharmacologica Sinica》《Science China Chemistry》《Communications in Theoretical Physics》《Computational Molecular Bioscience》更多>>; 相关基金：国家自然科学基金更多>>

Key amino acid residues govern the substrate selectivity of the transporter Xltr1p from Trichoderma reesei for glucose, mannose, and galactose: 《Engineering Microbiology》2024年第4期1-11,共11页Wei Ma Shiyu Yuan Zixian Wang Kangle Niu Fengyi Li Lulu Liu Lijuan Han Xu Fang; This work was supported by National Key R&D Program of China(No.2018YFA0901700);National Natural Science Foundation of China(No.32271526).; This research identified four amino acid residues(Leu174,Asn297,Tyr301,and Gln291)that contribute to sub-strate recognition by the high-affinity glucose transporter Xltr1p from Trichoderma reesei.Potential hotspots af...; 关键词：Hexose transporter GLUCOSE GALACTOSE MANNOSE Transmembrane α-helix 7 Sugar transport Computer-aided screening

Spontaneous Unfolding and Refolding of Plantaricin α-Helix in Molecular Dynamics Simulation: 《Computational Molecular Bioscience》2019年第1期27-39,共13页Shaomin Yan Guang Wu; Antimicrobial peptides are promising therapeutic agents in view of increasing resistance to conventional antibiotics. Antimicrobial peptides usually fold in α-helical, β-sheet, and extended/random-coil structures. T...; 关键词：ALPHA-HELIX ANTIMICROBIAL Peptides Protein FOLDING Plantaricin A

Different stapling-based peptide drug design:Mimicking α-helix as inhibitors of protein-protein interaction被引量：3: 《Chinese Chemical Letters》2018年第7期1088-1092,共5页Xiang Li Yan Zou Hong-Gang Hu; Peptide stapling strategy has been proven a promising solution in addressing two major pharmacological hurdles, proteolytic stability and membrane permeability, for small peptides as therapeutics. This stapling peptid...; 关键词：STAPLING PEPTIDE Α-HELIX Protein-protein interaction

Reversibly switching the conformation of short peptide through in-tether chiral sulfonium auxiliary: 《Chinese Chemical Letters》2018年第3期485-488,共4页Xiaodong Shi Yixiang Jiang Dan Yang Hui Zhao Yuan Tian Zigang Li; financial support from the National Natural Science Foundation of China(Nos. 21372023 and 81572198);Ministry of Science and Technology of the People's Republic of China(No. 2015DFA31590);the Shenzhen Science and Technology Innovation Committee(Nos. JSGG20140519105550503, JCYJ20150331100849958,JCYJ20150403101146313, JCYJ20160301111338144,JCYJ20160331115853521, JSGG20160301095829250 and ZDSYS201504301539161);the Shenzhen Peacock Program(No. KQTD201103); A chirality induced helicity method has been developed to modulate the peptide＇s biophysical and biochemical properties. We report herein a novel approach for reversibly switching the conformation of short constraint...; 关键词：Cyclic peptide Sulfonium Chiral center α-Helix Reversible Tether modification

Using Neural Networks to Predict Secondary Structure for Protein Folding被引量：1: 《Journal of Computer and Communications》2017年第1期1-8,共8页Ali Abdulhafidh Ibrahim Ibrahim Sabah Yasseen; Protein Secondary Structure Prediction (PSSP) is considered as one of the major challenging tasks in bioinformatics, so many solutions have been proposed to solve that problem via trying to achieve more accurate predi...; 关键词：Protein Secondary Structure Prediction (PSSP) NEURAL NETWORK (NN) Α-HELIX (H) Β-SHEET (E) Coil (C) Feed Forward NEURAL NETWORK (FNN) Learning Vector Quantization (LVQ) Probabilistic NEURAL NETWORK (PNN) Convolutional NEURAL NETWORK (CNN)

Consequences of Non-Uniformity in the Stoichiometry of Component Fractions within One and Two Loops Models of α-Helical Peptides: 《Journal of Biophysical Chemistry》2014年第4期125-133,共9页Walter F. Schmidt Cathleen J. Hapeman James Wachira Clayton G. Thomas; A 3-D electrostatic density map generated using the Wavefront Topology System and Finite Element Method clearly demonstrates the non-uniformity and periodicity present in even a single loop of an α-helix. The four di...; 关键词：Pattern Recognition Α-HELIX Dihedral Angle Patterns Peptide BACKBONE Sequence Molecular Orbital Theory Electrostatic Density Gradient Wavefront Topology System Finite Element Method

The vibron dressing in α-helicoidal macromolecular chains: 《Chinese Physics B》2013年第6期218-227,共10页D.evizovi S. Galovi A. Reshetnyak Z. Ivi; supported by the Science Fund of the Ministry of Education and Science of Republic of Serbia (Grant Nos. III–45005 and III–45010);by the Project within the Cooperation Agreement between the JINR, Dubna, Russian Federation;Ministry of Education and Science of Republic of Serbia; We present a study of the physical properties of the vibrational excitation in α-helicoidal macromolecular chains, caused by the interaction with acoustical and optical phonon modes. The influence of the temperature ...; 关键词：vibron SMALL-POLARON Α-HELIX partial dressing

Reversible folding/unfolding of small α-helix in explicit solvent investigated by ABEEMσπ/MM被引量：3: 《Science China Chemistry》2009年第11期1917-1924,共8页LIU Cui & YANG ZhongZhi Chemistry and Chemical Engineering Faculty,Liaoning Normal University,Dalian 116029,China; We have performed molecular dynamics simulations on the reversible folding/unfolding of small α-helix(short Ala based peptide Ala5) in explicit water solvent in terms of ABEEMσπ/MM.A dynamics analysis shows that t...; 关键词：REVERSIBLE folding/unfolding of protein Ala5 temperature hydrogen BOND

Features of Motion of Soliton Transported Bio-energy in Aperiodic α-Helix ProteinMolecules with Three Channels: 《Communications in Theoretical Physics》2009年第1期170-180,共11页PANG Xiao-Feng LIU Mei-Jie; supported by the National "973" Project of China under Grant No. 2007CB936103; The structure aperiodicities can influence seriously the features of motion of soliton excited in the α-helix protein molecules with three channels. We study the influence of structure aperiodicities on the features ...; 关键词：structure aperiodicity SOLITON stability PROTEIN BIO-ENERGY Runge-Kulta method

The effect of α-helix comformation on interaction between model oligopeptides and polymers: 《Chinese Science Bulletin》2008年第3期473-476,共4页LI JiHong DANG QinQin SUN HongWei CHA RuiTao YUAN Zhi; the National Natural Science Foundation of China(Grant Nos.50573034 and 20634030); The study of interactions between peptides and synthetic polymers has aroused considerable interest recently.In the present paper,the interaction mechanism between adsorbent DMAPAM and two pep-tides,VVRGCTWW(V8)and CT...; 关键词：低聚缩氨酸分子构造聚合物交互作用机制

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