Supported by Shenyang Innovation Foundation of Science and Technology–the Application Projects of Basic Research(No.F15-199-1-06);Liaoning Province Science and Technique Foundation of China(No.2015020282)
Objective: To investigate whether ginsenoside-Rb1(Gs-Rb1) improves the CoCl2-induced autophagy of cardiomyocytes via upregulation of adenosine 5’-monophosphate-activated protein kinase(AMPK) pathway. Methods: Ventric...
Supported by the National Natural Science Foundation of China:Study of Influence of Supplementing Qi and Activating Blood Circulation Herbs on Microvascular Dysfunction and Related Regulators of Myocardial Infarction Rats(No.81173142);Study of Influence of Supplementing Qi and Activating Blood Circulation Herbs on Mitochondrial Energy Metabolism and Signal Transduction of Myocardial Ischemia Rats(No.81473552);The Basic Research Program(graduate program)of Beijing university of Chinese Medicine:Study of Influence of Supplementing Qi and Activating Blood Circulation Herbs on Notch Signal Network of Myocardial Infarction Rats(No.2016-JYB-XS034)
OBJECTIVE: To investigate the effect of Yiqihuoxue prescription(YQHX) from Traditional Chinese Medicine(TCM) on myocardial glucose and lipid metabolism after myocardial infarction via the cross talk between the liver ...
Phosphatidylinositoi monophosphate 5-kinase (PIP5K) catalyzes the synthesis of PI-4,5-bispbosphate (Ptdlns(4,5) P2) by phosphorylation of PI-4-phosphate at the 5 position of the inositol ring, and is involved in...
Supported by The National Research Foundation of Korea Grant,Funded by the Korea Government(MEST),No.2010-0001706,South Korea
The adenosine monophosphate-activated protein kinase (AMPK) and p70 ribosomal S6 kinase-1 pathway may serve as a key signaling flow that regulates energy metabolism; thus, this pathway becomes an attractive target for...
Berberine(BBR) is a natural alkaloid isolated from the Coptis Chinensis.While this plant has been used in Ay-urvedic and Chinese medicine for more than 2500 years,interest in its effects in metabolic and cardiovascula...