RIBOSOMAL

作品数：118被引量：154H指数：6
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相关作者：杨大海李永平逄涛白戈李勇更多>>
相关机构：贵阳医学院贵州医科大学云南省烟草农业科学研究院中国科学技术大学更多>>
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Difference of the gut microbiota of premature ovarian insufficiency in two traditional Chinese syndromes
《Journal of Traditional Chinese Medicine》2025年第1期132-139,共8页WU Jiaman NING Yan TAN Liya MA Fei LIN Yanting ZHUO Yuanyuan 
Sanming Project of Medicine in Shenzhen:the First Affiliated Hospital of Guangzhou University of Traditional Chinese Medicine,Luo Songping National Famous Chinese Medicine Practitioner Female Reproductive Disorders Prevention and Treatment Team(SZZYSM202311010);Guangdong Provincial Administration of Traditional Chinese Medicine:Investigation of the Mechanism of Regulating Ren-Tong-Du Acupuncture on Ovarian Granulosa Cells in Polycystic Ovary Syndrome based on Activin A/Smads Signalling Pathway(No.20181229);Guangdong Provincial Administration of Traditional Chinese Medicine:Evaluation of the Efficacy of Menstrual Regulation and Pregnancy Promotion by Acupuncture in the Treatment of Premature Ovarian Insufficiency(No.20201294);Shenzhen Science and Innovation Commission:Investigating the Mechanism of Action of Acupuncture in Regulating the Gut Microbiome to Inhibit Apoptosis of Ovarian Granulosa Cells in Premature Ovarian Insufficiency Mice based on the Rictor/Torepamycin Target Protein C2 Pathway(No.JCYJ20210324130001004)。
PURPOSE:To investigate the differences in gut microbial characteristics between two traditional Chinese syndromes of premature ovarian insufficiency(POI).METHODS:Forty women with POI were recruited from the Department...
关键词：primary ovarian insufficiency gastrointestinal microbiome RNA ribosomal 16S gonadal steroid hormones traditional Chinese syndromes 
Correction: Ribosomal modification protein rimK-like family member A activates betaine-homocysteine S-methyltransferase 1 to ameliorate hepatic steatosis
《Signal Transduction and Targeted Therapy》2025年第1期471-472,共2页Han Yan Wenjun Liu Rui Xiang Xin Li Song Hou Luzheng Xu Lin Wang Dong Zhao Xingkai Liu Guoqing Wang Yujing Chi Jichun Yang 
Correction to:Signal Transduction and Targeted Therapy https://doi.org/10.1038/s41392-024-01914-0,published online 08 August 2024 In the process of collating the raw data,the authors noticed one inadvertent mistake in...
关键词：HEPATIC CORRECTION repeatedly 
SMYD5 is a ribosomal methyltransferase that catalyzes RPL40 lysine methylation to enhance translation output and promote hepatocellular carcinoma被引量：1
《Cell Research》2024年第9期648-660,共13页Bisi Miao Ling Ge Chenxi He Xinghao Wang Jibo Wu Xiang Li Kun Chen Jinkai Wan Shenghui Xing Lingnan Ren Zhennan Shi Shengnan Liu Yajun Hu Jiajia Chen Yanyan Yu Lijian Feng Natasha M.Flores Zhihui Liang Xinyi Xu Ruoxin Wang Jian Zhou Jia Fan Bin Xiang En Li Yuanhui Mao Jingdong Cheng Kehao Zhao Pawel K.Mazur Jiabin Cai Fei Lan 
supported in part by grants from the National Natural Science Foundation of China(31925010 to F.L.,82272703 to J.Cai,32300461 to C.H.);the National Key R&D Program of China(2021YFA1300100 to F.L.);the Elite Youth Project of Natural Science Foundation of Fujian Province(2023J06056 to J.Cai);the China National Postdoctoral Program for Innovative Talents(BX20230098 to C.H.).
While lysine methylation is well-known for regulating gene expression transcriptionally,its implications in translation have been largely uncharted.Trimethylation at lysine 22(K22me3)on RPL40,a core ribosomal protein ...
关键词：HEPATOCELLULAR markedly TRANSLATION 
Ribosomal modification protein rimK-like family member A activates betaine-homocysteine S-methyltransferase 1 to ameliorate hepatic steatosis
《Signal Transduction and Targeted Therapy》2024年第9期4048-4065,共18页Han Yan Wenjun Liu Rui Xiang Xin Li Song Hou Luzheng Xu Lin Wang Dong Zhao Xingkai Liu Guoqing Wang Yujing Chi Jichun Yang 
supported by National Natural Science Foundation of China(82300957/82230024/82025008/82070844);Beijing Natural Science Foundation(7212123).
Nonalcoholic fatty liver disease(NAFLD)is a serious threat to public health,but its underlying mechanism remains poorly understood.In screening important genes using Gene Importance Calculator(GIC)we developed previou...
关键词：METABOLISM HEPATIC HOMOCYSTEINE 
Beyond ribosomal function:RPS6 deficiency suppresses cholangiocarcinoma cell growth by disrupting alternative splicing
《Acta Pharmaceutica Sinica B》2024年第9期3931-3948,共18页Wenkang Fu Yanyan Lin Mingzhen Bai Jia Yao Chongfei Huang Long Gao Ningning Mi Haidong Ma Liang Tian Ping Yue Yong Zhang Jinduo zhang Yanxian Ren Liyun Ding Lunzhi Dai Joseph WLeung Jinqiu Yuan Wenhua Zhang Wenbo Meng 
the National Key Research and Development Program of China(2022YFC2407405);National Natural Science Foundation of China(82060551,32160230);Natural Science foundation of Gansu Province(22JR5RA891,China);Gansu Provincial Health Industry Research Program(GSWSQH2021-001,China);Science and Technology Bureau Talent Innovation Program of Chengguan District(2019RCCX0038,China).
Cholangiocarcinoma(CCA)is a bile duct malignancy with a dismal prognosis.This study systematically investigated the role of the ribosomal protein S6(RPS6)gene,which is dependent in CCA.We found that RPS6 upregulation ...
关键词：CHOLANGIOCARCINOMA Ribosomal protein S6 Alternative splicing p53 Minichromosome maintenance complex component 7 Vivo morpholino Patient-derived organoids 
Frequent recombination in Cynoglossus abbreviatus(Pleuronectiformes:Cynoglossidae)ribosomal 18S rDNA
《Acta Oceanologica Sinica》2024年第8期98-103,共6页Li Gong Tingqi Jiang Bilin Hu Kaixin Wang Nannan Zhang Zengliang Miao 
The Basic Scientific Research Operating Expenses of Zhejiang Provincial Universities under contract 2021JZ003;the Zhoushan Science and Technology Bureau under contract No.2021C21007;the Natural Science Foundation of Zhejiang Province under contract Y21C190023;the National Natural Science Foundation of China under contract 31272273.
The conventional theory of concerted evolution has been used to explain the lack of sequence variation in ribosomal RNA(rRNA)genes across diverse eukaryotic species.However,recent investigations into rRNA genes in fla...
关键词：ribosomal RNA tongue sole non-concerted evolution PSEUDOGENE crossing over gene conversion 
PABP-driven secondary condensed phase within RSV inclusion bodies activates viral mRNAs for ribosomal recruitment
《Virologica Sinica》2024年第2期235-250,共16页Qiang Zhang Hanzhe Ye Cong Liu Haiwu Zhou Mingbin He Xiaodong Liang Yu Zhou Kun Wang Yali Qin Zhifei Li Mingzhou Chen 
supported by the grants from National Key R&D Program of China(2021YFC2300702 and 2021YFC2300200);the Hubei Provincial Natural Science Foundation of China(2021CFB364);the National Natural Science Foundation of China(82130064,81825015,U22A20337 and 32000119);the Key Biosafety Science and Technology Program of Hubei Jiangxia Laboratory(JXBS001).
Inclusion bodies(IBs)of respiratory syncytial virus(RSV)are formed by liquid-liquid phase separation(LLPS)and contain internal structures termed“IB-associated granules”(IBAGs),where anti-termination factor M2-1 and ...
关键词：Respiratory syncytial virus(RSV) Inclusion bodies(IBs) Biomolecular condensates Liquid-liquid phase separation(LLPS) Secondary condensed phase mRNA activation 
Visualizing the nucleoplasmic maturation of human pre-60S ribosomal particles被引量：1
《Cell Research》2023年第11期867-878,共12页Yunyang Zhang Xiaomeng Liang Sha Luo Yan Chen Yu Li Chengying Ma Ningning Li Ning Gao 
supported by the National Natural Science Foundation of China (32230051 to N.G.,31922036 to N.L.);the National Key R&D Program of China (2019YFA0508904 to N.G.);the Qidong-SLS Innovation Fund to N.G.
Eukaryotic ribosome assembly is a highly orchestrated process that involves over two hundred protein factors.After early assembly events on nascent rRNA in the nucleolus,pre-60S particles undergo continuous maturation...
关键词：DETAILS STEPS successive 
Effects of Zhenggan Huayu decoction(正肝化瘀方)combined with entecavir on gut microbiota in patients with chronic hepatitis B fibrosis被引量：1
《Journal of Traditional Chinese Medicine》2023年第3期559-567,共9页CHEN Wenlin LIANG Fang ZHANG Yuncheng LV Jinzhen YANG Daguo 
Supported by Shenzhen Science and Technology Plan Project:Study on the Mechanism of Zhenggan Huayu Decoction Regulating Intestinal Flora in Liver Fibrosis based on LPS-TRL4 Signal Pathway(No.JCYJ20180302150216419)。
OBJECTIVE:To evaluate the effects of Zhenggan Huayu decoction(正肝化瘀方,ZGHY) combined with entecavir(ETV) on the gut microbiota in patients with chronic hepatitis B(CHB) fibrosis.METHODS:A total of 59 CHB-related fi...
关键词：hepatitis B CHRONIC FIBROSIS RNA RIBOSOMAL 16S Zhenggan Huayu decoction ENTECAVIR gut microbiota 
Microbial community structure of different tongue fur types in patients with chronic gastritis
《Journal of Traditional Chinese Medicine》2023年第2期365-373,共9页WANG Yanan YUAN Li WANG Li XU Zhiyuan RUAN Hua CHENG Xiangdong DONG Changwu 
Supported by National Natural Science Foundation of China:Study on the Mechanism of New Sophora Japonica Extract Inhibiting the Formation of Liver Pre Metastasis Microenvironment by Down Regulating the Gastric Cancer Cell-Derived Exosome ITGB5(No.81973634);Key Research And Development Plan of Anhui Province:Development And Application of TCM Health Status Identification System Based on Artificial Intelligence Tongue Diagnosis(No.2022h11020018);Key Projects of Anhui Provincial Department of Education:Research on Key Technologies of Artificial Intelligence Tongue Color Recognition Based on Machine Learning(No.KJ2020A0379)。
OBJECTIVE:To explore the correlation between tongue and oral microbiota,we studied the microbial community structure of different tongue coating types in patients with chronic gastritis.METHODS:16S rDNA gene sequencin...
关键词：GASTRITIS medicine Chinese traditional RNA ribosomal 16S oral microflora tongue manifestation 
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