Supported by the National Natural Science Foundation of China(the Study on Intervention and Mechanism of Chinese Herbal Medicines for Nourishing Qi and Resolving Blood Stasis on Cytoskeletal Protein of Vascular Aging(No.81273976);the Mechanism of Exploration about Formula for Reinforcing Qi,Warming Yang,Activating Blood and Promoting Diuresis in the Prevention and Treatment of Heart Failure through mT ORC1-Mitophagy Pathway(No.8170-3865);Independent Research Program of the China Academy of Chinese Medical Sciences(the Study on Mechanism of Chinese Herbal Medicines for Nourishing Qi and Resolving Blood Stasis Delaying Vascular Aging(No.zz2013002);the Mechanism of Exploration about Formula for Reinforcing Qi,Warming Yang,Activating Blood and Promoting Diuresis in the Prevention and Treatment of Heart Failure through Nrf2-iron Death Pathway(No.zz13-YQ-034);Beijing Science and Technology Bureau(Clinical study about Formula for Reinforcing Qi,Warming Yang,Activating Blood and Promoting Diuresis to Improve the Survival Status of Patients with Chronic Heart Failure(No.Z171100001017108)。
OBJECTIVE: To investigate the effects of extracts from Renshen(Radix Ginseng), Sanqi(Radix Notoginseng), and Chuanxiong(Rhizoma Chuanxiong) on the endothelial actin cytoskeleton in senescent human cardiac microvascula...
Fibrosis is a phenomenon of fibrous connective tissue increase in the organs. Activated hepatic stellate cells (HSCs) are the preferred targets of anti-hepatic fibrotic therapies. Ginseng and Platycodon grandiflorum...
Supported by National Natural Science Foundation of China(No.30973828);Major State Basic Research Development Program of China(937 Program,No.2007CB507400);Self-Project Foundation from China Academy of Chinese Medical Sciences(No.Z02151)
Objective:To observe the time-effect relation of extracts from ginseng,notoginseng and chuanxiong on angiotensin II(AngⅡ)-induced senescence of vascular endothelial cells and explore the feature of Chinese medicin...
Supported by the National Basic Research Program of China (Program 937,No.2007CB507400);the National Natural Science Foundation of China(No.30973828);the Independent Topic Program of China Academy of Chinese Medical Sciences (No.Z02151)
Objective: To observe the effect of extracts from Radix Ginseng, Radix Notoginseng and Rhizoma Chuanxiong (EXT) on delaying vascular smooth muscle cells (VSMCs) aging in aged rats. Methods: VSMCs were obtained b...
AIM: To determine the concentration of acetylcholine (ACh) in amyloid beta-protein (Aβ) treated rats and offer a method determining ACh as well. METHODS: A 1-month combination of extrats of ginseng and ginkgo biloba ...
AIM:To examine the efficacy of Saenghyuldan and its components,Ginseng Radix ,Paeoniae Radix Alba,and Hominis Placentsa extracts (SHD,GR,PRA,and HP,respectively) on the hempopoiesis in a myelosuppression model system...