REJUVENATION

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Why stem/progenitor cells lose their regenerative potential被引量:1
《World Journal of Stem Cells》2021年第11期1714-1732,共19页Angela Picerno Alessandra Stasi Rossana Franzin Claudia Curci Ighli di Bari Loreto Gesualdo Fabio Sallustio 
Nowadays,it is clear that adult stem cells,also called as tissue stem cells,play a central role to repair and maintain the tissue in which they reside by their selfrenewal ability and capacity of differentiating into ...
关键词:Stem cells AGING SELF-RENEWAL REJUVENATION Aging-associated disorders Epigenetic changes Aging environment 
Senescent mesenchymal stem/stromal cells and restoring their cellular functions被引量:3
《World Journal of Stem Cells》2020年第9期966-985,共20页Qing-Shu Meng Jing Liu Lu Wei Hui-Min Fan Xiao-Hui Zhou Xiao-Ting Liang 
Supported by the National Natural Science Foundation of China,Nos.81500207,81670458,and 81470393;Shanghai Municipal Health and Family Planning Commission,No.ZY(2018-2020)-FWTX-2007;Shanghai Key Medical Discipline for Critical Care Medicine,No.2017zz02017;the National Key Research and Development Program of China,No.2017YFA0105600;Major Program of Development Fund for Shanghai Zhangjiang National Innovtaion Demonstration Zone,No.ZJ2018-ZD-004;the Science and Technology Commission of Shanghai Municipality,No.17431906600;and the Top-level Clinical Discipline Project of Shanghai Pudong,No.PWYgf2018-05.
Mesenchymal stem/stromal cells(MSCs)have various properties that make them promising candidates for stem cell-based therapies in clinical settings.These include self-renewal,multilineage differentiation,and immunoregu...
关键词:Mesenchymal stem cells SENESCENCE Features Function Rejuvenation strategy 
Aging: A cell source limiting factor in tissue engineering被引量:4
《World Journal of Stem Cells》2019年第10期787-802,共16页Mohammadhossein Khorraminejad-Shirazi Mohammadreza Dorvash Alireza Estedlal Amir Human Hoveidaei Mohsen Mazloomrezaei Pouria Mosaddeghi 
Tissue engineering has yet to reach its ideal goal,i.e.creating profitable off-theshelf tissues and organs,designing scaffolds and three-dimensional tissue architectures that can maintain the blood supply,proper bioma...
关键词:AGING SENESCENCE REJUVENATION Geroprotection TISSUE engineering Stem CELL therapy 
Tendon stem/progenitor cell ageing: Modulation and rejuvenation被引量:2
《World Journal of Stem Cells》2019年第9期677-692,共16页Guang-Chun Dai Ying-Juan Li Min-Hao Chen Pan-Pan Lu Yun-Feng Rui 
Supported by the National Natural Science Foundation of China,No.81871812 and No.81572187;National Natural Science Foundation of China for Young Scholars,No.81201422;Natural Science Foundation of Jiangsu Province for Young Scholars,No.BK2012334;“Summit of the Six Top Talents” Program of Jiangsu Province,No.2013-WSW-054;Jiangsu Provincial Medical Talent,The Project of Invigorating Health Care through Science,Technology and Education,No.ZDRCA2016083;The Six Projects Sponsoring Talent Summits of Jiangsu Province,China,No.LGY2017099
Tendon ageing is a complicated process caused by multifaceted pathways and ageing plays a critical role in the occurrence and severity of tendon injury.The role of tendon stem/progenitor cells(TSPCs)in tendon maintena...
关键词:TENDON stem/progenitor cell Ageing MECHANISMS MODULATION REJUVENATION 
Preventing aging with stem cell rejuvenation:Feasible or infeasible?被引量:1
《World Journal of Stem Cells》2017年第1期1-8,共8页Kanya Honoki 
Supported by The Ministry of Education,Culture,Sports,Science and Technology in Japan,No.15K10455
Characterized by dysfunction of tissues, organs, organ systems and the whole organism, aging results fromthe reduced function of effective stem cell populations. Recent advances in aging research have demonstrated tha...
关键词:AGING Stem cell NICHE REJUVENATION SIGNALING PATHWAY 
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