supported in part by the Beijing Natural Science Foundation of China(L232077,7242092,7222117);the National Natural Science Foundation of China(82000812);the China Postdoctoral Science Foundation(2023M733682).
Since its identification as a marker for advanced melanoma in the 1980s,CD146 has been found to have multiple functions in both physiological and pathological processes,including embryonic development,tissue repair an...
supported by the National Natural Science Foundation of China(82172592);the Free Exploration Program of Central South University(2021zzts0934);the program of Introducing Talents of Discipline to Universities(111-2-12)。
Ferroptosis is an iron-dependent regulatory cell necrosis induced by iron overload and lipid peroxidation.It occurs when multiple redoxactive enzymes are ectopically expressed or show abnormal function.Hence,the preci...
supported by the National Natural Science Foundation of China (82273903)。
The protein PINK1 plays a crucial role in the regulation of the cellular autophagic hierarchy.Autophagy,a highly conserved biological process,serves as a mechanism for the degradation of intracellular components by ly...
sponsored by the National Natural Science Foundation of China(31771065);Sichuan Science and Technology Program(2019JDRC0020);the“1.3.5 Program for Disciplines of Excellence,”West China Hospital,Sichuan University(ZYJC18002)。
Exosomes are nano-scale extracellular vesicles secreted by cells and constitute an important part in the cell-cell communication.The main contents of the exosomes include proteins,micro RNAs,and lipids.The mechanism a...
partly supported by grants from the National Key Research and Development Program of China(2017YFA0104500);National Natural Science Foundation of China(81670168);the Key Program of National Natural Science Foundation of China(81230013)。
Acute graft-versus-host disease(a GVHD)is caused by allo-activated donor T cells infiltrating target organs.As a regulator of immune function,granulocyte colony-stimulating factor(G-CSF)has been demonstrated to reliev...
supported by the National Natural Science Foundation of China(31670091 and 31470177)
In filamentous fungi,nitrogen metabolism is repressed by GATA-type zinc finger transcription factors.Nitrogen metabolite repression has been found to affect antibiotic production,but the mechanism is still poorly unde...
supported by the National Natural Science Foundation of China (31430087);the Scientific and Technological Research Project of Harbin (2014AB3AN058);the Special Fund for Scientific and Technological Innovative Talents of Harbin (2014RFQYJ129);the Modern Agro-industry Technology Research System of China (nycytx-42-G3-01)
To test whether amino acid mutations in the PBC and PHI loops of VP2 are involved in the replication and virulence of infectious bursal disease virus(IBDV), a pair of viruses, namely the moderately virulent IBDV(rG x-...
the National Natural Science Foundation of China (31301369, 31271768, 31401425)
Long noncoding RNAs (lncRNAs) play important roles in various biological regulatory processes in yeast, mammals, and plants. However, no systematic identification of lncRNAs has been reported in Gossypium arboreum. ...
Abscisic acid (ABA) was originally identified in the early 1960s, and was thought to be involved in fruit and leaf ab- scission. Over the past 50 years, ABA was intensely studied and has become one of the vital plan...
supported by the National Natural Science Foundation of China (81100164,31271212,81070196,81030001);the Research Fund for the Doctoral Program of Higher Education (20100001110101,20110001120015);the Program for New Century Excellent Talents in University,the Beijing Talents Foundation
Although microRNAs (miRNAs) have been intensively studied in cardiac fibrosis, their roles in drug-mediated anti-fibrotic therapy are still unknown. Previously, Pioglitazone attenuated cardiac fibrosis and increased...