supported by the National Natural Science Foundation of China(32188102,32372118,32071993);the Qian Qian Academician Workstation,and the specific research fund of the innovation platform for academicians of Hainan Province(YSPTZX202303);the Nanfan special project,CAAS(ZDXM2315);Hainan Seed Industry Laboratory,China(B21HJ0220);the Key Research and Development Program of Zhejiang Province(2021C02056)。
Tillers are unique inflorescence-like branches in grasses,and their number determines the panicle number,plant architecture,and yield(Shang et al.,2021).Tiller formation mainly undergoes axillary meristem(AM)initiatio...
supported by the National Natural Science Foundation of China(32201963);Scientific Research Foundation of Hunan Provincial Education Department(22C0137).
D-Mannose is an attractive functional sugar that exhibits many physiological benefits on human health.The demand for low-calorie sugars and sweeteners in foods are increasingly available on the market.Some sugar isome...
supported by the National Natural Science Foundation of China (Nos. 22077138 to S. Wu, 81725020 to C. Sheng;81872742 to G. Dong);the National Key Research and Development Program of China (No. 2020YFA0509200 to C. Sheng);Shanghai Rising-Star Program (No. 22QA1411300 to S. Wu)。
Inspired by the indolopyridoquinazoline scaffold of natural products evodiamine and rutaecarpine, novel triple G4 and Top1/2 ligands were rationally designed and synthesized. Systematic structure–activity relationshi...
supported by grants from National Natural Science Foundation of China(No.81073018 and 81274044)to Rufeng Wang;Startup fund program at Beijing University of Chinese Medicine(90011451310011);key research fund for drug discovery in Chinese medicine at Beijing University of Chinese Medicine(1000061223476)to Wenfu Ma。
The C-glycosidic bond that connects the sugar moiety with aglycone is difficult to be broken or made due to its inert nature.The knowledge of C-glycoside breakdown and synthesis is very limited.Recently,the enzyme Dgp...
supported by grants from the National Natural Science Foundation of China(No.82072813);Natural Science Foundation of Guangdong Province(No.2020A1515010473 and No.2018A030313668);China Postdoctoral Science Foundation(No.2020M682666).
The limited treatment options for advanced prostate cancer(PCa)lead to the urgent need to discover new anticancer drugs.Mannose,an isomer of glucose,has been reported to have an anticancer effect on various tumors.How...
supported by the National Natural Science Foundation of China(31700206);the Natural Science Basic Research Program of Shaanxi(2016JM3023);the Special Scientific Research Project of Education Department of Shaanxi Province(16JK1792)。
In plant chloroplasts,photosystem II(PSII)complexes,together with light-harvesting complex II(LHCII),form various PSII-LHCII supercomplexes(SCs).This process likely involves immunophilins,but the underlying regulatory...
Supported by the National Natural Science Foundation of China(No.41676124)。
Abstract The unfolded protein response(UPR)is an important protective and compensatory strategy used during endoplasmic reticulum stress caused by factors including glucose starvation,low pH,or heat shock.However,ther...
supported by grants from the Ministry of Agriculture of China (2016ZX08009003);the National Natural Science Foundation of China (31670279, 31770398);the Ministry of Science and Technology of China (2013CBA01400)。
Lateral branching is an important determinant of shoot architecture and crop yield. The plant hormone strigolactone (SL) inhibits lateral bud outgrowth in various plant species. Deficiencies in SL biosynthesis and sig...
grants from the Chinese Ministry of Science and Technology(2016YFD0100901);the Ministry of Agriculture of China(2016ZX08011001);the CAS President’s International Fellowship Initiative(2018VBA0025);the Youth Innovation Promotion Association CAS(2019099);the Strategic Priority Research Program of CAS(XDB27010100)(Beltran et al.,2015).
Rice tillering is an important agronomic trait affecting grain yield.Here,we identified a high-tillering mutant tillering20(t20),which could be restored to the wild type by treatment with the strigolactone(SL)analog r...
supported by the Ministry of Science and Technology(2019YFA0801703);the National Natural Science Foundation of China(81790250,81790253 and 91959202);the Innovation Program of Shanghai Municipal Education Commission(N173606)。
Cancer cells remodel their metabolic network to adapt to variable nutrient availability. Pentose phosphate pathway(PPP) plays protective and biosynthetic roles by oxidizing glucose to generate reducing power and ribos...