ISATINS

作品数:13被引量:13H指数:2
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相关领域:理学化学工程更多>>
相关期刊:《Natural Science》《Organic Chemistry Frontiers》《Chinese Journal of Chemistry》《Neuroscience & Medicine》更多>>
相关基金:国家自然科学基金中国博士后科学基金高等学校学科创新引智计划更多>>
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UV light-driven asymmetric vinylogous aldol reaction of isatins with 2-alkylbenzophenones and enantioselective synthesis of 3-hydroxyoxindoles
《Organic Chemistry Frontiers》2022年第3期643-648,共6页Shixuan Cao Jiatian Li Taishan Yan Jie Han Zhengjie He 
Financial support from the National Natural Science Foundation of China(Grant No.22171143,21472096 and J1103306)is gratefully acknowledged.
Chiral 3-hydroxyoxindoles are biologically important molecular motifs which are frequently present in natural products and artificial compounds.Herein,we report an ultraviolet light-driven asymmetric vinylogous aldol ...
关键词:conditions ASYMMETRIC ALKYL 
Copper-Catalyzed Aerobic Oxidative Ring Expansion of Isatins: A Facile Entry to Isoquinolino-Fused Quinazolinones被引量:1
《Chinese Journal of Chemistry》2021年第1期87-92,共6页Dahan Wang Fuhong Xiao Feng Zhang Huawen Huang Guo-Jun Deng 
This work was supported by the National Natural Science Foundation of China(21871226,21502160 and 21572194);Scien-tific Research Fund of Hunan Provincial Education Department(19B564);Hunan Provincial Natural Science Foundation of China(2020113032);Efficient Resource Uilization,the China Postdoc-toral Science Foundation(2018M632976 and 2019T120709);Scientific Research Fund of Xiangtan University(XDCX2020B110).
A copper-catalyzed aerobic oxidative ring expansion reaction of isatins with 1,2,3,4-tetrahydroisoquinoline for the synthesis of tetra-cyclic quinazolinones has been developed.This reaction is performed smoothly under...
关键词:Copper catalysis Oxidation CYCLIZATION QUINAZOLINONES C-H Activation 
HFIP-promoted catalyst-free cascade reactions for the synthesis of biologically relevant 3,3-di(indolyl)indolin-2-ones from indoles and isatins
《Chinese Chemical Letters》2020年第9期2465-2468,共4页Xiaohan Yuan Shuai Wang Jialing Cheng Bin Yu Hong-Min Liu 
supported by the National Natural Science Foundation of China(Nos.81773562,81703326 and 81973177);The Open Project of State Key Laboratory of Natural Medicines(No.SKLNMKF202005);China Postdoctoral Science Foundation(Nos.2018M630840 and 2019T120641)。
The first HFIP-promoted catalyst-free cascade reactions for the synthesis of biologically relevant 3,3-di(indolyl)indolin-2-ones(27 examples,up to 98% yield) from readily available indoles and isatin derivatives are d...
关键词:INDOLES ISATINS HFIP Catalyst-free synthesis 3 3-Di(indoly)indolin-2-ones 
Dimethyl sulfoxide-aided copper(0)-catalyzed intramolecular decarbonylative rearrangement of N-aryl isatins leading to acridones
《Chinese Chemical Letters》2020年第6期1580-1583,共4页Hao Wu Nana Ma Mengxiao Song Guisheng Zhang 
National Natural Science Foundation of China(Nos.U1604285 and 21877206);the Program for Changjiang Scholars and Innovative Research Team in University of China(No.IRT1061);the 111 Project(No.D17007)。
Described here is the first example of Cu(0)-catalyzed intramolecular decarbonylative rearrangements of readily available N-aryl isatins assisted by solvent dimethyl sulfoxide(DMSO)under air atmosphere and additive-fr...
关键词:Cu(0)-catalyzed decarbonylation Decarbonylative rearrangements DMSO-aided reactions N-Aryl isatins ACRIDONES 
Oxidative Rearrangement of Isatins with Arylamines Using H2O2 as Oxidant: A Facile Synthesis of Quinazoline-2,4-diones and Evaluation of Their Antibacterial Activity被引量:3
《Chinese Journal of Chemistry》2017年第12期1835-1843,共9页Guanghao Shi Xinwei He Yongjia Shang Cheng Yang Liwei Xiang 
Supporting information for this article is available on the WWW under http://dx.doi.org/10.1002/cjoc,201700280 or from the author.Acknowledgement The work was partially supported by the National Natural Science Foundation of China (No. 21172001, 21372008), the Natural Science Foundation of Education Administration of Anhui Province (KJ2016A267), the Special and Excellent Research Fund of Anhui Normal University and the Doctoral Scientific Research Foundation of Anhui Normal University (No. 2016XJJ110).
A green and highly efficient synthetic method for the synthesis of quinazoline-2,4-diones with hydrogen peroxide as the terminal oxidant has been developed, The reaction features the mild reaction conditions, broad su...
关键词:antibacterial activity hydrogen peroxide ISATINS quinazoline-2 4-diones rearrangement 
[3+3] Formal Cycloadditions of Nitrones from Isatins and Azaoxyallyl Cations for Construction of Spirooxindoles被引量:1
《Chinese Journal of Chemistry》2017年第6期857-860,共4页Weijia Lin Gu Zhan Minglin Shi Wei Du Yingchun Chen 
A [3+3] formal cycloaddition reaction between in situ formed azaoxyallyl cations and nitrones from isatins has been developed, furnishing a spectrum of spiro[1,2,4-oxadiazinan-5-one]oxindoles in good to excellent yie...
关键词:CYCLOADDITION SPIROOXINDOLES azaoxyallyl cations NITRONES 1 3-dipoles 
Synthesis of 3',4'-Diaryl-4'H-spiro[indoline-3,5'-[1',2',4']- oxadiazol]-2-ones via DMAP-catalyzed Domino Reactions and Their Antibacterial Activity
《Chinese Journal of Chemistry》2016年第9期901-909,共9页Guanghao Shi Xinwei He Yongjia Shang Liwei Xiang Cheng Yang Guang Han Bing Du 
The work was partially supported by the National Natural Science Foundation of China (Nos. 21172001, 21372008), the Natural Science Foundation of Education Administration of Anhui Province (No. KJ2016A267), the Special and Excellent Research Fund of Anhui Normal University and the Doctoral Scientific Research Foundation of Anhui Normal University (No. 2016XJJ110).
A convenient and metal-flee DMAP-catalyzed domino reaction of isatins, arylamines and hydroximoyl chlorides has been developed to achieve 1,3-dipolar cycloaddition of imines into aryl nitrile oxides at ambient tempera...
关键词:4-DIMETHYLAMINOPYRIDINE antimicrobial activity ISATINS domino reactions OXADIAZOLES 
Synthesis and antibacterial activity of Schiff bases of 5-substituted isatins被引量:6
《Chinese Chemical Letters》2016年第2期221-225,共5页Kamaleddin Haj Mohammad Ebrahim Tehrani Maryam Hashemi Maryam Hassan Farzad Kobarfard Shohreh Mohebbi 
Based on the existing reports on the bioactive isatin derivatives, a number of Schiff bases were synthesized by reacting 5-substituted isatins with bioactive amines/hydrazides and their structures were confirmed using...
关键词:SYNTHESIS ISATIN Schiff base HYDANTOIN ANTIBACTERIAL 
Brominelpara-Toluenesulfonic Acid-Catalyzed Synthesis of 3,3-Bis(indole-3-yl)indoline-2-(1H)-ones by Condensing Indoles with Isatins被引量:1
《Chinese Journal of Chemistry》2015年第10期1167-1172,共6页Wenzhong Huang Lingli Nang Xiangguang Li Lin Yuan Yinhai Ma Deqiang Liang 
Under the catalysis of only 3 mol% of Br2 at room temperature, indoles reacted rapidly with isatins to form bio- logically important 3,3-bis(indole-3-yl)indoline-2-(1H)-ones with high efficiency and wide substrate...
关键词:homogeneous catalysis bromine effect indole functionalization C--C coupling alkylation 
Synthesis of new type of Betti bases via three-component reaction of b-naphthol,cyclic amines and isatins被引量:1
《Chinese Chemical Letters》2015年第3期353-356,共4页Hong Gao Jing Sun Chao-Guo Yan 
supported by the National Natural Science Foundation of China (No.21272200);the Priority Academic Program Development of Jiangsu Higher Education Institutions
This work provided the first example of incorporating the oxindole moiety into the Betti bases.The new type of Betti bases were conveniently synthesized in good yields from the three-component reaction of b-naphthol,i...
关键词:bases moiety amines conveniently methylene pyrrolidine benzyl antibacterial chelate aldehydes 
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