Financial support from the National Natural Science Foundation of China(Grant No.22171143,21472096 and J1103306)is gratefully acknowledged.
Chiral 3-hydroxyoxindoles are biologically important molecular motifs which are frequently present in natural products and artificial compounds.Herein,we report an ultraviolet light-driven asymmetric vinylogous aldol ...
This work was supported by the National Natural Science Foundation of China(21871226,21502160 and 21572194);Scien-tific Research Fund of Hunan Provincial Education Department(19B564);Hunan Provincial Natural Science Foundation of China(2020113032);Efficient Resource Uilization,the China Postdoc-toral Science Foundation(2018M632976 and 2019T120709);Scientific Research Fund of Xiangtan University(XDCX2020B110).
A copper-catalyzed aerobic oxidative ring expansion reaction of isatins with 1,2,3,4-tetrahydroisoquinoline for the synthesis of tetra-cyclic quinazolinones has been developed.This reaction is performed smoothly under...
supported by the National Natural Science Foundation of China(Nos.81773562,81703326 and 81973177);The Open Project of State Key Laboratory of Natural Medicines(No.SKLNMKF202005);China Postdoctoral Science Foundation(Nos.2018M630840 and 2019T120641)。
The first HFIP-promoted catalyst-free cascade reactions for the synthesis of biologically relevant 3,3-di(indolyl)indolin-2-ones(27 examples,up to 98% yield) from readily available indoles and isatin derivatives are d...
National Natural Science Foundation of China(Nos.U1604285 and 21877206);the Program for Changjiang Scholars and Innovative Research Team in University of China(No.IRT1061);the 111 Project(No.D17007)。
Described here is the first example of Cu(0)-catalyzed intramolecular decarbonylative rearrangements of readily available N-aryl isatins assisted by solvent dimethyl sulfoxide(DMSO)under air atmosphere and additive-fr...
Supporting information for this article is available on the WWW under http://dx.doi.org/10.1002/cjoc,201700280 or from the author.Acknowledgement The work was partially supported by the National Natural Science Foundation of China (No. 21172001, 21372008), the Natural Science Foundation of Education Administration of Anhui Province (KJ2016A267), the Special and Excellent Research Fund of Anhui Normal University and the Doctoral Scientific Research Foundation of Anhui Normal University (No. 2016XJJ110).
A green and highly efficient synthetic method for the synthesis of quinazoline-2,4-diones with hydrogen peroxide as the terminal oxidant has been developed, The reaction features the mild reaction conditions, broad su...
A [3+3] formal cycloaddition reaction between in situ formed azaoxyallyl cations and nitrones from isatins has been developed, furnishing a spectrum of spiro[1,2,4-oxadiazinan-5-one]oxindoles in good to excellent yie...
The work was partially supported by the National Natural Science Foundation of China (Nos. 21172001, 21372008), the Natural Science Foundation of Education Administration of Anhui Province (No. KJ2016A267), the Special and Excellent Research Fund of Anhui Normal University and the Doctoral Scientific Research Foundation of Anhui Normal University (No. 2016XJJ110).
A convenient and metal-flee DMAP-catalyzed domino reaction of isatins, arylamines and hydroximoyl chlorides has been developed to achieve 1,3-dipolar cycloaddition of imines into aryl nitrile oxides at ambient tempera...
Based on the existing reports on the bioactive isatin derivatives, a number of Schiff bases were synthesized by reacting 5-substituted isatins with bioactive amines/hydrazides and their structures were confirmed using...
Under the catalysis of only 3 mol% of Br2 at room temperature, indoles reacted rapidly with isatins to form bio- logically important 3,3-bis(indole-3-yl)indoline-2-(1H)-ones with high efficiency and wide substrate...
supported by the National Natural Science Foundation of China (No.21272200);the Priority Academic Program Development of Jiangsu Higher Education Institutions
This work provided the first example of incorporating the oxindole moiety into the Betti bases.The new type of Betti bases were conveniently synthesized in good yields from the three-component reaction of b-naphthol,i...