supported by the National Natural Science Foundation of China (Nos.32160303 and 31760165);the Education Department of Jiangxi Province (No.GJJ211001);the Scientific and Technological Project of Ji’an City (No.20211–025333);the Key Project of Natural Science Foundation of Jiangxi Province (2022)。
Antibiotic resistance genes(ARGs)can be easily promoted by antibiotics,however,the structural effects of antibiotics on the proliferation of ARGs dynamic and the associated mechanisms remain obscure in,especially,acti...
Coccidiosis is a disease caused by protozoa of the genus Eimeria which seriously affects young rabbits. Treatment based on the use of anticoccidial drugs is increasingly ineffective due to the rapid emergence of resis...
Some novel sulfonamide-derivatives were designed to develop novel kinase inhibitors. The molecular docking study was performed for the designed compounds against epidermal growth factor kinase receptor T790M/L858R (TM...
This work was supported by“National Key Research and Development Program of China”(Project No.2018YFC1603400);Science and Technology Program of Hebei Province(Project No.19225503D).
The aim of this work was to develop an automated on-line solid phase extraction(SPE)with liquid chromatography-tandem mass spectrometry method for the detection of fifteen sulfonamides in pork and fish samples.Samples...
Acetazolamide(molecular mass(MM),222)belongs to the class of sulfonamides(R-SO2-NH2)and is one of the strongest pharmacological inhibitors of carbonic anhydrase activity.Acetazolamide is excreted unchanged in the urin...
This project was supported by the National Natural Science Foundation of China(No.21876143);Science and Technology Program of Henan Province(No.172102210088);Nanhu Scholars Program for Young Scholars of XYNU。
OH addition reactions of cationic,neutral and anionic forms of three sulfonamides(sulfamethoxazole,sulfadiazine and sulfapyridine)in aqueous solution were theoretically studied using density functional theory(DFT)meth...
Supported by the National High Technology Research and Development Program of China(No.2011AA100805) and the National Natural Science Foundation of China(No.20875037).
An environmentally friendly method for extracting sulfonamides(SAs) residues from animal feed was described and applied. The method used online microwave-assisted steam extraction coupled with solid phase extraction...
supported by the National Nature Science Foundation of China (No. 51406109)
In this paper, we propose a novelmethod based on the plate theory to simultaneously predict retention times and peak shapes under gradient elutions and different flow rates by reversed-phase high-performance liquid ch...
Natural Science Foundation of China for the financial support(Grant No.30772626)
On the basis of the Michael-addition mechanism of classical proteasome inhibitors, six dipeptide vinyl sulfonamide and dipeptide vinyl sulfonate derivatives were designed and synthesized. Moreover, an efficient method...
Supported by Agricultural Science and Technology Achievement Transformation Project of the Ministry of Science and Technology of China(2012GB2A200045);Science and Technology Support Program of Science and Technology Department of Hebei Province(10960408D);Post-award Grant Program from the Department of Science and Technology of Hebei Province(15926620H);Science and Technology Research Project for Colleges and Universities in Hebei Province(QN20131123)
[ Objective] This study aimed to analyze antibiotic sensitivity and detect sulfonamide resistance gene Sul2 in 17 Escherichia coli isolates from swine. [ Method] The antibiotic sensitivity of 17 E. coil isolates from ...