SULFONAMIDE

作品数:73被引量:62H指数:4
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相关领域:理学医药卫生更多>>
相关作者:池志宏牛犁王月王占友缪晓玲更多>>
相关机构:西南大学中国医科大学清华大学宁德师范高等专科学校更多>>
相关期刊:《光谱学与光谱分析》《International Journal of Organic Chemistry》《Agricultural Biotechnology》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划宁德师专科研基金国家高技术研究发展计划更多>>
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Design, Synthesis and Characterization of Novel Sulfonamides Derivatives as Anticancer Agent Targeting EGFR TK, and Development of New Methods of Synthesis by Microwave Irradiation
《International Journal of Organic Chemistry》2021年第4期199-223,共25页Souad Akili Djamila Ben Hadda Yaser Bitar Amir Balash Mustapha Fawaz Chehna 
Some novel sulfonamide-derivatives were designed to develop novel kinase inhibitors. The molecular docking study was performed for the designed compounds against epidermal growth factor kinase receptor T790M/L858R (TM...
关键词:SULFONAMIDE Anticancer EGFR TMLR 5EDQ Molegro Virtual Docker Sul-famethoxazole SULFANILAMIDE Microwave 
Monitoring intracellular pH fluctuation with an excited-state intramolecular proton transfer-based ratiometric fluorescent sensor
《Chinese Chemical Letters》2021年第10期3057-3060,共4页Bin Feng Yingli Zhu Jiaxin Wu Xueyan Huang Rong Song Liu Huang Xueping Feng Wenbin Zeng 
the financial supports from National Natural Science Foundation of China (Nos.81971678 and 81671756);the Innovation Fund for Postgraduate Students of Central South University (No.2019zzts1019)。
Intracellular pH is a key parameter related to various biological and pathological processes.In this study,a ratiometric pH fluorescent sensor ABTT was developed harnessing the amino-type excited-state intramolecular ...
关键词:Excited-state intramolecular proton transfer Intracellular pH SULFONAMIDE Ratiometric sensor Fluorescent imaging 
Rapid analysis of fifteen sulfonamide residues in pork and fish samples by automated on-line solid phase extraction coupled to liquid chromatography–tandem mass spectrometry被引量:7
《Food Science and Human Wellness》2020年第4期363-369,共7页Junmei Ma Sufang Fan Lei Sun Liangna He Yan Zhang Qiang Li 
This work was supported by“National Key Research and Development Program of China”(Project No.2018YFC1603400);Science and Technology Program of Hebei Province(Project No.19225503D).
The aim of this work was to develop an automated on-line solid phase extraction(SPE)with liquid chromatography-tandem mass spectrometry method for the detection of fifteen sulfonamides in pork and fish samples.Samples...
关键词:Liquid chromatography–tandem mass SPECTROMETRY On-line solid phase extraction SULFONAMIDES Internal standard quantification 
Synthesis, Crystal Structure and Antibacterial Activity of New N-(1H-benzo[d]imidazol-2-yl)benzenesulfonamide Derivatives of Dehydroabietic Acid被引量:1
《Chinese Journal of Structural Chemistry》2020年第8期1539-1545,1362,共8页CAI Xu-Min LI A-Liang LIN Yu-Ting WANG Wen-Yan WANG Shi-Fa GU Wen 
supported by the National Natural Science Foundation of China(31770616 and 21601087);the Natural Science Foundation for Colleges and Universities in Jiangsu Province(17KJA220002);Top-notch Academic Programs Project of Jiangsu Higher Education Institutions(PPZY2015C221)。
The title compounds(7a^7g)were synthesized from dehydroabietic acid and characterized by spectroscopic methods including HR-MS,1H-and 13C-NMR.The crystal structure of compound 7g determined by single-crystal X-ray dif...
关键词:dehydroabietic acid BENZIMIDAZOLE SULFONAMIDE crystal structure antibacterial activity 
Computational Study on OH Addition Reactions of Three Sulfonamides in Aqueous Solution
《Chinese Journal of Structural Chemistry》2020年第1期48-56,2,共10页ZENG Xiao-Lan SUN Xiao-Zi WANG He-Yu YU Yong-Sheng 
This project was supported by the National Natural Science Foundation of China(No.21876143);Science and Technology Program of Henan Province(No.172102210088);Nanhu Scholars Program for Young Scholars of XYNU。
OH addition reactions of cationic,neutral and anionic forms of three sulfonamides(sulfamethoxazole,sulfadiazine and sulfapyridine)in aqueous solution were theoretically studied using density functional theory(DFT)meth...
关键词:addition reaction SULFONAMIDE OH RADICALS REACTIVITY order position SELECTIVITY 
Synthesis,Crystal Structure and Evaluations of Its Cytotoxicity,Anti-microbial and Anti-hydroxyl Radical Activities of a New Co-crystal Compound(C6H6Cl2N2O2S)·(Phen)·H2O
《Chinese Journal of Structural Chemistry》2018年第7期1078-1086,共9页黄岚珍 王雅楠 蔡卓 秦秀英 
Supported by Guangxi Natural Science Foundation(No.2016GXNSFAA380292);National Natural Science Foundation of China(No.21661011)
Co-crystal is a very potential kind of drug solid forms, and has a far-reaching influence on designing and preparing drugs. A new 1:1:1 co-crystal compound consisting of 4-amino-3,5-dichloro-benzenesulfonamide, 1,10...
关键词:4-amino-3 5-dichloro-benzenesulfonamide CO-CRYSTAL CYTOTOXICITY ANTI-MICROBIAL anti-hydroxyl radical 
Simultaneous Prediction of Retention Times and Peak Shapes of Sulfonamides in Reversed-Phase High-Performance Liquid Chromatography
《Transactions of Tianjin University》2018年第3期256-262,共7页Xiaobing Wei Zhengji Pang Guoliang Fan Xinhua Xu Lihong Wang 
supported by the National Nature Science Foundation of China (No. 51406109)
In this paper, we propose a novelmethod based on the plate theory to simultaneously predict retention times and peak shapes under gradient elutions and different flow rates by reversed-phase high-performance liquid ch...
关键词:Retention time Peak shape PREDICTION RP-HPLC SULFONAMIDE 
An Efficient Method for Sulfonylation of Amines, Alcohols and Phenols with N-Fluorobenzenesulfonimide Under Mild Conditions
《Chemical Research in Chinese Universities》2018年第2期191-196,共6页JING Li YU Xinling GUAN Mei WU Xiaohua WANG Qiantao WU Yong 
Supported by the National Natural Science Foundation of China(Nos. 81373259, 81573286).
A new and convenient procedure was developed for the preparation of sulfonamides and sulfonic esters using N-fluorobenzenesulfonimide(NFSI) as a novel phenylsulfonyl group transfer reagent. In this protocol, a broad...
关键词:N-Fluorobenzenesulfonimide SULFONYLATION SULFONAMIDE Sulfonic ester 
Sulfonamide and Morpholine-Based Dual Chemosensor for Cu^2+ and Ag^+ in Different Solvent Media
《Chinese Journal of Chemistry》2016年第9期931-936,共6页Fang Hu Rui Li Jinjian Wang Luyan He Xing Li Jun Yin Shenghua Liu 
This work was supported by National Natural Science Foundation of China (Nos. 20931006, 21072070, 21272088 and 21571110), the Program for Academic Leader in Wuhan Municipality (No. 201271130441), the Natural Science Foundation of Ningbo City (No. 2016A610051) and financially supported by research funds of NBU (No. ZX2015000586).
The detection of cations has attracted considerable interest because of their importance in various physiological processes. In this study, compound 1 bearing sulfonamidc and morpholine functionalities was synthesized...
关键词:SULFONAMIDE MORPHOLINE multifunctional chemosensor CATION density functional theory 
Vibrational Spectroscopic Study of N-[4-[1-Hydroxy-2-[(1-Methyl Ethyl)Amino]Ethyl]Phenyl]Methane Sulfonamide被引量:1
《光谱学与光谱分析》2016年第3期880-886,共7页N.Balamurugan S.Sampathkrishnan C.Charanya 
The vibrational spectral analysis was carried out by using FT-Raman and FT-IR spectroscopy in the range 4 000~400and 4 000~400cm-1 respectively,for N-[4-[1-hydroxy-2-[(1-methyl ethyl)amino]ethyl]phenyl]methane sulfona...
关键词:FT-IR FT-RAMAN DFT Vibrational analysis 
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