BIOLOGIC

作品数：117被引量：190H指数：7
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Genetic factors that predict response and failure of biologic therapy in inflammatory bowel disease
《World Journal of Experimental Medicine》2025年第1期11-23,共13页Milena Peruhova Daniela Stoyanova Dimitrina Georgieva Miteva Meglena Kitanova Milko Bozhidarov Mirchev Tsvetelina Velikova 
Supported by The European Union-Next Generation EU,through the National Recovery and Resilience Plan of the Republic of Bulgaria,No.BG-RRP-2.004-0008。
Inflammatory bowel disease(IBD)represents a significant disease burden marked by chronic inflammation and complications that adversely affect patients’quality of life.Effective diagnostic strategies involve clinical ...
关键词：Inflammatory bowel disease Genetic predictors Inflammatory bowel disease treatment Biologic therapy Biologic therapy response Genetic markers in inflammatory bowel disease Inflammatory bowel disease treatment failure PHARMACOGENOMICS Biologic therapy efficacy Genetic variability 
Biologics in the management of pediatric inflammatory bowel disease:When and what to choose
《World Journal of Clinical Pediatrics》2025年第1期21-45,共25页Arghya Samanta Anshu Srivastava 
Pediatric inflammatory bowel disease(PIBD)is a chronic inflammatory disorder of the gastrointestinal tract,with rising global incidence and prevalence.Over the past two decades,biologics have added to the therapeutic ...
关键词：BIOLOGICS CHILDREN Inflammatory bowel disease Therapeutic drug monitoring Dual biologic 
DNA-based recyclable moist-electric generator
《Friction》2025年第2期57-62,共6页Tianlei Guang Yaxing Huang Haiyan Wang Tiancheng He Kaixuan Zhu Yujuan Zhang Hongfei Shang Jian Li Huhu Cheng Liangti Qu 
supported by the financial support from the National Natural Science Foundation of China(22075165,22035005,52350362,22205129,52090032,and 52022051);Tsinghua-Foshan Innovation Special Fund(2020THFS0501);supported by Shanxi Province Science and Technology Cooperation and Exchange Special Project(202204041101028);the Shanxi Provincial Key Laboratory of Advanced Carbon Electrode Materials(202104010910019).
Recently developed moist-electric generator(MEG)can spontaneously produce electricity after absorbing water from the air,delivering an interesting and novel power harvesting process.The employment of environment-frien...
关键词：moist-electric generator(MEG) DNA biological substrates electricity generation 
Outcomes of a 12-month course of early and late rituximab BCD020 biosimilar administration in juvenile systemic lupus erythematosus:A retrospective study
《World Journal of Nephrology》2024年第4期81-90,共10页Elvira Kalashnikova Eugenia Isupova Ekaterina Gaidar Natalia Lubimova Lyubov Sorokina Irina Chikova Maria Kaneva Rinat Raupov Olga Kalashnikova Damir Aliev Inna Gaydukova Mikhail Kostik 
Supported by Ministry of Science and Higher Education of the Russian Federation,No.075-15-2022-301;the Russian Science Foundation Grant,No.22-45-08004.
BACKGROUND Juvenile systemic lupus erythematosus(SLE)is a severe,life-threatening disease.However,the role of rituximab in managing juvenile SLE remains undefined,although early biological intervention may improve dis...
关键词：Systemic lupus erythematosus RITUXIMAB Rituximab BCD020 biosimilar Anti-CD-20 BIOLOGIC Children 
The Use of Biologic Treatments for Osteoarthritis: A Review
《Open Journal of Regenerative Medicine》2024年第2期21-40,共20页William Thornton Sion Glyn-Jones 
Background: The number of people presenting with osteoarthritis is increasing due, largely, to an ageing population and advances in medical treatments. This is driving the demand for new clinical solutions and treatme...
关键词：OSTEOARTHRITIS BIOLOGICS Gene Therapy Stem Cell Protein Therapy 
A core-satellite self-assembled SERS aptasensor containing a“biological-silent region”Raman tag for the accurate and ultrasensitive detection of histamine被引量：1
《Food Science and Human Wellness》2024年第2期1029-1039,共11页Chen Chen Yingfang Zhang Ximo Wang Xuguang Qiao Geoffrey I.N.Waterhouse Zhixiang Xu 
financially supported by the National Natural Science Foundation of China(31972149);funding support from the MacDiarmid Institute for Advanced Materials and Nanotechnology;the Dodd-Walls Centre for Photonic and Quantum Technologies。
Herein,a novel interference-free surface-enhanced Raman spectroscopy(SERS)strategy based on magnetic nanoparticles(MNPs)and aptamer-driven assemblies was proposed for the ultrasensitive detection of histamine.A core-s...
关键词：Surface-enhanced Raman spectroscopy Raman biological-silent region APTAMER Histamine detection Universal SERS-tag 
Lighting up plants with near-infrared fluorescence probes
《Science China Chemistry》2024年第3期774-787,共14页Yida Pang Mengjiao Lu Hyeonji Rha Wenchao Yang Amit Sharma Yao Sun Jong Seung Kim 
supported by the National Natural Science Foundation of China(U20A2038,22022404,21977036,22074050);the CRI Project of National Research Foundation of Republic of Korea(2018R1A3B1052702);Department of Biotechnology,New Delhi,India,for prestigious DBT-Ramalingaswami fellowship(BT/RLF/Re-entry/59/2018);Science&Engineering Research Board,New Delhi(CRG/2021/002476)。
Fluorescence imaging is a non-invasive and highly sensitive bioimaging technique that has shown remarkable strides in plant science. It enables real-time monitoring and analysis of biological and pathological processe...
关键词：NIR fluorescent probe PLANT imaging biologic application 
Primary repair for concurrent bilateral intertrochanteric fracture and femoral head necrosis with prolonged shank biologic total hip replacement: A case report and surgical techniques
《Chinese Journal of Traumatology》2023年第3期183-186,共4页Yuan-Jie Liu Jun-Tan Li Yu-Yang Gao Pei-Yan Guo Tian-Xu Dou Xu Li 
For the treatment of an intertrochanteric fracture combined with femoral head necrosis in middle-age patients,it has been controversial whether to perform fracture reduction and fixation first then total hip replaceme...
关键词：BILATERAL Primary hip replacement Femoral head necrosis Intertrochanteric fracture Greater trochanteric plate 
Chest wall osteochondroma resection with biologic acellular bovine dermal mesh reconstruction in pediatric hereditary multiple exostoses:A case report and review of literature被引量：1
《World Journal of Clinical Cases》2023年第17期4123-4132,共10页Abdullah Alshehri 
BACKGROUND Hereditary multiple exostoses is a rare genetic disorder characterized by the growth of multiple osteochondromas affecting primarily long bones.Chest wall lesions may represent a challenge,particularly in p...
关键词：Hereditary multiple exostoses Chest wall neoplasm Chest wall reconstruction Biologic mesh PEDIATRIC Case report 
Emerging role of dual biologic therapy for the treatment of inflammatory bowel disease被引量：2
《World Journal of Clinical Cases》2023年第12期2621-2630,共10页Matthew D McCormack Natasha A Wahedna David Aldulaimi Peter Hawker 
Biologic agents have now been used in the management of inflammatory bowel disease(IBD)for many years where experience,expertise and confidence in their use has developed over time.In the United Kingdom,there are well...
关键词：Dual biologic therapy Inflammatory bowel disease Crohn’s disease Ulcerative colitis Combination therapy Biologic safety 
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