NANOGELS

作品数：35被引量：55H指数：4
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相关领域：理学一般工业技术更多>>
相关作者：熊玉兵周剑锋叶晓东张淑彦刘小兵更多>>
相关机构：西北师范大学华东师范大学中国科学技术大学中国药科大学更多>>
相关期刊：《Bioactive Materials》《Agricultural Biotechnology》《Engineering》《Chinese Journal of Chemical Physics》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划河南省自然科学基金中国博士后科学基金更多>>
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pH-responsive AIE nanogels for synergistic chemo-photodynamic cancer therapy with imaging guidance
《Science China Chemistry》2025年第4期1445-1455,共11页Yilin Zhu Liping Zhang Rongyuan Zhang Chenghan He Han Yang Yong Liu Ryan T.K.Kwok Jacky W.Y.Lam Jianwei Sun Jing Feng Zheng Zhao Cuiping Yao Ben Zhong Tang 
supported by the National Key Research and Development Program of China(2023YFB3810001);the National Natural Science Foundation of China(62175198,52333007,U22A2092,and 52273197);the Shenzhen Key Laboratory of Functional Aggregate Materials(ZDSYS20211021111400001);the Science,Technology and Innovation Commission of Shenzhen Municipality(JCYJ2021324134613038,KQTD20210811090142053,JCYJ20220818103007014,andGJHZ20210705141810031);the Innovation and Technology Commission(ITC-CNERC14SCO1);the Science and Technology Program of Guangzhou,China(2023A04J0069);the Fundamental Research Funds for the Central Universities(xtr062022002 and xzy022022007)。
Photodynamic therapy(PDT)is a promising cancer treatment that uses photosensitizers(PSs)to generate cytotoxic reactive oxygen species(ROS)under light;but improving its efficacy is crucial for clinical applications.To ...
关键词：photodynamic therapy aggregation-induced emission pH-responsive nanogels imaging-guided synergistic cancer therapy 
ROS-sensitive PD-L1 siRNA cationic selenide nanogels for self-inhibition of autophagy and prevention of immune escape
《Bioactive Materials》2024年第11期597-610,共14页Jie Gao Yonghua Zhai Weihong Lu Xianghe Jiang Jingsheng Zhou Lili Wu Longhai Du Chunqing Ou Xinyi Zhang Hanliang He Jian Zhu Zhengbiao Zhang Meiyun Li Yan Wu Xiangqiang Pan 
National Natural Science Foundation of China(No.21971177,82072051);Natural Science Foundation of the Jiangsu Higher Education Institution of China(No.22KJA150004);Priority Academic Program Development(PAPD)of Jiangsu Higher Education Institutions;Jiangsu Key Laboratory of Advanced Functional Polymers Design and Application,Soochow University;Suzhou Key Laboratory of Macromolecular Design and Precision Synthesis and the Program of Innovative Research Team of Soochow University.
In the field of cancer therapy,inhibiting autophagy has emerged as a promising strategy.However,pharmacological disruption of autophagy can lead to the upregulation of programmed death-ligand 1(PD-L1),enabling tumor i...
关键词：Multicomponent reaction ROS sensitive Cationic nanogel Autophagy inhibition Immune escape 
Research Progress of Zhuang Medicine Combined with Nanogels in Mastitis
《Agricultural Biotechnology》2024年第2期68-71,共4页Liying XU Chunling YANG Yeting LE Lianzhi TAN Liying TAN Ting LIU 
Supported by Undergraduate Training Program for Innovation and Entrepreneurship of Guangxi University of Chinese Medicine in 2023(S202310600116)。
Mastitis is a common and frequently-occurring disease among Chinese women, which seriously harms their mental and physical health. External application of Zhuang medicine has the effects of dredging collaterals, relie...
关键词：MASTITIS Zhuang medicine NANOGEL OVERVIEW 
A ROS-Sensitive Diselenide-Crosslinked Polymeric Nanogel for NIR Controlled Release
《Chinese Journal of Polymer Science》2023年第3期386-393,I0007,共9页Ji-Chao Hu Qi-Hua Zhang Qiu-Qin Mu Yi-Yuan Tang Zhen Wu Guo-Jie Wang 
financially supported by the National Natural Science Foundation of China (No. 51373025);the Program for New Century Excellent Talents in University (No. NCET-110582)。
Here we report a novel polymeric nanogel with stable loading cargo and near-infrared(NIR) controlled release properties.The nanogels are crosslinked by quaternization reactions of biocompatible poly(β-amino esters) a...
关键词：NANOGELS NIR responsiveness Diselenide-crosslinked Controlled release 
The immune-chemo-embolization effect of temperature sensitive gold nanomedicines against liver cancer被引量：2
《Nano Research》2023年第2期2749-2761,共13页Yiming Liu Dingwen Shi Yanqiao Ren Ling Li Yanbing Zhao Chuansheng Zheng Xiangliang Yang 
supported by the National Basic Research Program of China(Nos.2020YFA0710700 and 2018YFA0208900);the National Natural Science Foundation of China(Nos.82172758,81873919,and 81801810).
Although transcatheter arterial chemo-embolization(TACE)plays a key role on clinical treatment of hepatocellular carcinoma(HCC),it was greatly limited by the poor synergistic effect between chemotherapeutics and physi...
关键词：temperature sensitive nanogels gold nanoparticles transcatheter arterial chemo-embolization(TACE) antitumor immune response 
Desalted duck egg white nanogels as Pickering stabilizers for food-grade oil-in-water emulsion
《Food Science and Human Wellness》2022年第5期1306-1314,共9页Jingyun Zhao Xiaohan Guo Ze Chen Yalei Dai Hongshan Liang Qianchun Deng Shugang Li Bin Zhou 
financially supported by the National Natural Science Foundation of China(Grant No.32172354);the Opening Project of Key Laboratory of Oilseeds processing,Ministry of Agriculture and Rural Affairs(202003);the Doctoral Research Startup Fund of Hubei University of Technology(BSQD2017027)。
Achieving the reuse of traditional egg by-products,salted duck egg whites(SEW),is an urgent problem to be solved.In this current work,we constructed a heat-induced gel-assisted desalination method for SEW.Subsequently...
关键词：Salted duck egg white DESALINATION Protein nanogels Pickering emulsion Stability 
Microenvironment-responsive chemotherapeutic nanogels for enhancing tumor therapy via DNA damage and glutathione consumption被引量：1
《Chinese Chemical Letters》2022年第9期4197-4202,共6页Mengjie Ye Yuan Gao Mengyun Liang Wei Qiu Xian bin Ma Jiming Xu Junfeng Hu Peng Xue Yuejun Kang Zhigang Xu 
financially supported by the Chongqing Graduate Program of Research and Innovation (No. CYS21110);the National Natural Science Foundation of China (Nos. 51703187, 32071375);Chongqing Talents of Exceptional Young Talents Project, China (Nos. CQYC202005029 and cstc2021ycjh-bgzxm0061)
Although targeted therapy and immunotherapy are now shining in the treatment of some cancers,chemotherapy is still the cornerstone of drug treatment for many cancer patients.The emergence of chemotherapy prodrugs can ...
关键词：NANOGEL PRODRUG GSH-responsive DNA damage Chemotherapy 
Near-infrared chemiluminescent carbon nanogels for oncology imaging and therapy被引量：4
《SmartMat》2022年第2期269-285,共17页Chenglong Shen Tianci Jiang Qing Lou Wenbo Zhao Chaofan Lv Guangsong Zheng Hangrui Liu Pengfei Li Lingling Dai Kaikai Liu Jinhao Zang Feng Wang Lin Dong Songnan Qu Zhe Cheng Chongxin Shan 
the National Natural Science Foundation of China(Nos.12074348,U2004168,U1904142,and U21A2070);the China Postdoctoral Science Foundation(No.2020M682310);the Natural Science Foundation of Henan Province(No.212300410078);Science and Technology Department of Henan Province(No.182102410010).
Carbon nanogels(CNGs)with dual ability of reactive oxygen species(ROS)imaging and photodynamic therapy have been designed with selfassembled chemiluminescent carbonized polymer dots(CPDs).With efficient deep-red/near-...
关键词：cancer therapy carbon nanogels CHEMILUMINESCENCE inflammation imaging 
Dendrimer-decorated nanogels:Efficient nanocarriers for biodistribution in vivo and chemotherapy of ovarian carcinoma被引量：3
《Bioactive Materials》2021年第10期3244-3253,共10页Xin Li Zhijun Ouyang Helin Li Chaolei Hu Pabitra Saha Lingxi Xing Xiangyang Shi Andrij Pich 
This research was financially supported by the Sino-German Center for Research Promotion(GZ1505),DFG(SFB 985,Functional Microgels and Microgel Systems),National Natural Science Foundation of China(81801704 and 81761148028);Science and Technology Commission of Shanghai Municipality(18520750400);Shanghai Sailing Program(18YF1415300)。
Nanomedicine has revolutionized disease theranostics by the accurate diagnosis and efficient therapy.Here,the PAMAM dendrimer decorated PVCL-GMA nanogels(NGs)were developed for favorable biodistribution in vivo and en...
关键词：NANOGELS DENDRIMER Surface charge Thermal/pH dual-responsiveness Drug delivery 
Incorporating redox-sensitive nanogels into bioabsorbable nanofibrous membrane to acquire ROS-balance capacity for skin regeneration被引量：3
《Bioactive Materials》2021年第10期3461-3472,共12页Shihao Zhang Yamin Li Xiaofeng Qiu Anqi Jiao Wei Luo Xiajie Lin Xiaohui Zhang Zeren Zhang Jiachan Hong Peihao Cai Yuhong Zhang Yan Wu Jie Gao Changsheng Liu Yulin Li 
The research was supported by National Key R&D Program of China(2018YFE0201500,2017YFB0309300);National Natural Science Foundation of China(81772317,51973060,82072051,81771964);National Natural Science Foundation of China for Innovative Research Groups(51621002);Natural Science Foundation of Heilongjiang Province(LH2020H076);Shanghai International Cooperation Program(15520721200);Central Universities(WD1714002);The funding grants from Joint research project of important diseases in Xuhui District(XHLHGG201802);Fundamental Research Funds for the Shanghai Municipal Commission of Health and Family Planning(201740034)were also acknowledged.
Facing the high incidence of skin diseases,it is urgent to develop functional materials with high bioactivity for wound healing,where reactive oxygen species(ROS)play an important role in the wound healing process mai...
关键词：POLYLACTIDE Nanofibrous membrane Redox sensitivity ROS-Balance capacity Skin regeneration 
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