NANOMOTORS

作品数：27被引量：38H指数：5
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H_(2)S and NIR light-driven nanomotors induce disulfidptosis for targeted anticancer therapy by enhancing disruption of tumor metabolic symbiosis
《Chinese Chemical Letters》2025年第1期427-432,共6页Shangqian Zhang Jiaxuan Li Xuan Hu Zelong Chen Junliang Dong Chenhao Hu Shuang Chao Yinghua Lv Yuxin Pei Zhichao Pei 
supported by the National Natural Science Foundation of China(No.22171230);the Project of Science and Technology of Social Development in Shaanxi Province(Nos.2024SF-YBXM-294,2023-YBSF-151)。
Disulfidptosis,a novel mechanism of programmed cell death through the disruption of tumor metabolic symbiosis(TMS),has showed tremendous potential in cancer therapy.However,the efficacy of disulfidptosis is limited by...
关键词：H_(2)S NIR light NANOMOTORS Disulfidptosis Tumor metabolic symbiosis 
An NIR-propelled janus nanomotor with enhanced ROS-scavenging,immunomodulating and biofilm-eradicating capacity for periodontitis treatment
《Bioactive Materials》2024年第11期271-292,共22页Xuan Bai Wenan Peng Ying Tang Ziming Wang Jingmei Guo Fangfang Song Hongye Yang Cui Huang 
Fundamental Research Funds for the Central Universities(2042022kf1206);National Natural Science Foundation of China(82271010).
Periodontitis is an inflammatory disease caused by bacterial biofilms,which leads to the destruction of periodontal tissue.Current treatments,such as mechanical cleaning and antibiotics,struggle to effectively address...
关键词：PERIODONTITIS NANOMOTORS Photothermal therapy Reactive oxygen species Biofilm eradication OSTEOGENESIS 
Author correction to“Gas-propelled nanomotors alleviate colitis through the regulation of intestinal immunoenvironmenthematopexis-microbiota circuits”[Acta Pharm Sin B 14(2024)2732-2747]
《Acta Pharmaceutica Sinica B》2024年第9期4193-4193,共1页Bo Xiao Yuqi Liang Ga Liu Lingshuang Wang Zhan Zhang Libin Qiu Haiting Xu Sean Carr Xiaoxiao Shi Rui LReis Subhas CKundu Zhenhua Zhu 
The authors regret that there are errors in the author information and author contributions.The name of the corresponding author,Zhenghua Zhu,should be corrected to Zhenhua Zhu.The modification does not affect the res...
关键词：journal CORRECTION contributions 
Gas-propelled nanomotors alleviate colitis through the regulation of intestinal immunoenvironment-hematopexis-microbiota circuits
《Acta Pharmaceutica Sinica B》2024年第6期2732-2747,共16页Bo Xiao Yuqi Liang Ga Liu Lingshuang Wang Zhan Zhang Libin Qiu Haiting Xu Sean Carr Xiaoxiao Shi Rui LReis Subhas CKundu Zhenghua Zhu 
supported by the National Natural Science Foundation of China(82072060,82360110,and 22008201);the Fundamental Research Funds for the Central Universities(SWU-XDPY22006,China);the Venture&Innovation Support Program for Chongqing Overseas Returnees(2205012980212766,China);the Distinguished Young Scholars of Chongqing(2022NSCQ-JQX5279,China);the Science and Technology Department of Jiangxi Province(20212BDH81019 and 20224BAB206073,China).
The progression of ulcerative colitis(UC)is associated with immunologic derangement,intestinal hemorrhage,and microbiota imbalance.While traditional medications mainly focus on mitigating inflammation,it remains chall...
关键词：NANOMOTOR ANTI-INFLAMMATION Blood coagulation Immune regulation Hematopexis Microbiota rebalance Ulcerative colitis Rectal administration 
Chemotactic nanomotor for multimodal combined therapy of glioblastoma
《Science China Chemistry》2024年第4期1277-1288,共12页Ting Li Lin Chen Yunxin Xue Xiangyu Xiao Wenjun Dai Kaiyuan Tan Tiantian Chen Yingfang Tao Chun Mao Jian Shen Mimi Wan 
supported by the National Natural Science Foundation of China(22175096,22275095);the Social Development Project of Jiangsu Natural Science Foundation(BE2019744);the Qinglan Project Foundation of Colleges and Universities of Jiangsu Province;the Jiangsu Collaborative Innovation Center of Biomedical Functional Materials;the Priority Academic Program Development of Jiangsu Higher Education Institution;the Postgraduate Research&Practice Innovation Program of Jiangsu Province(KYCX22_1545)。
Glioblastoma(GBM) is the most aggressive malignant brain tumor. Due to the infiltration and heterogeneity of GBM, the obstruction of the blood-brain barrier(BBB) and the unique immunosuppressive mechanism, it is hard ...
关键词：CHEMOTAXIS combined therapy GLIOBLASTOMA NANOMOTORS 
Chemical-NIR dual-powered CuS/Pt nanomotors for tumor hypoxia modulation,deep tumor penetration and augmented synergistic phototherapy被引量：1
《Journal of Materials Science & Technology》2023年第17期171-185,共15页Wenjun Wang Enhui Ma Pengyu Tao Xiaoyu Zhou Yujuan Xing Liang Chen Yingying Zhang Jingjing Li Kai Xu Hong Wang Shaohui Zheng 
financially supported by the National Natural Science Foundation of China(Nos.81901798,21905303,82172005);the Promotion Fund for Youth Talent of Jiangsu Association for Science and Technology(No.TJ-2021-069);the Startup Fund for Youth Talent in Xuzhou Medical University(No.D2019022);the Open Fund of Xuzhou Medical University(No.XYKF202102);the Fundamental Research Funds for the Central Universities(Nos.2020ZDPY0213,2022YCPY0205);the Natural Science Foundation of Jiangsu Province(Nos.BK20220161,BK20220663);the Jiangsu High-level Innovation and entrepreneurship Talent Project(No.RC5042001);the Jiangsu Province 6th“333 Project”of Cultivation of High-level Talents.
The complex tumor microenvironment(TME)with the characteristics of severe hypoxia,enriched hydro-gen peroxide(H_(2)O_(2))and dense nature significantly restricted the therapeutic efficacy of nanomedicine in cancer tre...
关键词：CuS/Pt Janus nanomotors Chemical-NIR dual-propulsion Deep tumor penetration Hypoxia alleviation Synergistic PDT and PTT 
Visible light triggered exfoliation of COF micro/nanomotors for efficient photocatalysis
《Green Energy & Environment》2023年第2期567-578,共12页Kai Feng Liang Zhang Jiang Gong Jinping Qu Ran Niu 
supported by Huazhong University of Science and Technology(No.2021XXJS036,3004013134);National Natural Science Foundation of China(No.51903099,82002879,22102059);the Innovation and Talent Recruitment Base of New Energy Chemistry and Device(No.B21003);China Postdoctoral Science Foundation(2021M692475,2021T140524,XJ2021037);support from the 100 Talents Program of the Hubei Provincial Government。
We report a new facile light-induced strategy to disperse micron-sized aggregated bulk covalent organic frameworks(COFs)into isolated COFs nanoparticles.This was achieved by a series of metal-coordinated COFs,namely C...
关键词：Micro/nanomotor COFs EXFOLIATION NANOCATALYST PHOTOCATALYSIS 
Near-infrared light-driven multifunctional metal ion(Cu^(2+))-loaded polydopamine nanomotors for therapeutic angiogenesis in critical limb ischemia被引量：1
《Nano Research》2023年第4期5108-5120,共13页Liang Gui Juju Huang Yi Xing Yongjun Li Junjie Zou Yingwei Zhu Xiao Liang Xiwei Zhang Qiang Xu Xin Du 
supported by the National Natural Science Foundation of China(No.82170515);Open Research Fund of Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy(No.XZSYSKF2021038);Jiangsu Funding Program for Excellent Postdoctoral Talent,and Changzhou Municipal Health Commission Science and Technology Project(No.ZD202126).
Most of the current nanomedicine-based treatments for critical limb ischemia(CLI)only aim at promoting angiogenesis,ignoring the negative influence on the therapeutic effects caused by the complex pathological micro-e...
关键词：NANOMOTORS POLYDOPAMINE near-infrared(NIR)light COPPER therapeutic angiogenesis 
Recent Advances in One‑Dimensional Micro/Nanomotors:Fabrication,Propulsion and Application被引量：2
《Nano-Micro Letters》2023年第2期114-142,共29页Yuhong Zheng He Zhao Yuepeng Cai Beatriz Jurado‑Sanchez Renfeng Dong 
supported by General Project of Natural Science Foundation of Guangdong Province(2022A1515010715);Guangzhou Basic and Applied Basic Research Project(202102020638);Science and Technology Planning Project of Guangdong Province(2017B090917002,2019B1515120027 and 2019A050510038);Research and development plan projects in key areas of Guangdong Province(2020B0101030005);supported by Grant PID2020-118154GB-I00 funded by MCIN/AEI/https://doi.org/10.13039/501100011033,Grant TED2021-132720B-I00,funded by MCIN/AEI/https://doi.org/10.13039/501100011033;the European Union“NextGenerationEU”/PRTR(B.J.S);the Community of Madrid[grant number CM/JIN/2021-012(B.J.S)]。
Due to their tiny size,autonomous motion and functionalize modifications,micro/nanomotors have shown great potential for environmental remediation,biomedicine and micro/nano-engineering.One-dimensional(1D)micro/nanomo...
关键词：1D micro/nanomotors Fabrication methods Driving mechanisms Applications 
Medical micro-and nanomotors in the body
《Acta Pharmaceutica Sinica B》2023年第2期517-541,共25页Huaan Li Fei Peng Xiaohui Yan Chun Mao Xing Ma Daniela A.Wilson Qiang He Yingfeng Tu 
supported by the National Natural Science Foundation of China(Grant No.22175083,51973241,82001845,52072095,92163109 and 22193033)。
Attributed to the miniaturized body size and active mobility,micro-and nanomotors(MNMs)have demonstrated tremendous potential for medical applications.However,from bench to bedside,massive efforts are needed to addres...
关键词：Micro-and nanomotors Function integration Controlled propulsion In vivo navigation Biomedical applications Minimally invasive microsurgery BIOSENSING Biological barrier penetration 
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