supported by the National Natural Science Foundation of China(Grant Nos.32270692,31801104,31571358);the National Key R&D Program of China(Grant No.2018YFA0903700).
DNA replication is a complex and crucial biological process in eukaryotes.To facilitate the study of eukaryotic replication events,we present a database of eukaryotic DNA replication origins(DeOri),which collects geno...
supported by the National Natural Science Foundation of China(32125006,32070437);China National Postdoctoral Program for Innovative Talents(BX2021277);China Postdoctoral Science Foundation(2021M690144);Natural Science Foundation of Shandong Province of China(ZR2021QC046);Postdoctoral Applied Research Project of Qingdao.
Clipping of the histone H3 N-terminal tail has been implicated in multiple fundamental biological processes for a growing list of eukaryotes.H3 clipping,serving as an irreversible process to permanently remove some po...
Silicified and phosphatized microfossils preserved in the Ediacaran Doushantuo Formation in South China provide key evidence for the early radiation of eukaryotes after the Neoproterozoic global glaciations.
Land plants and algae form a supergroup, the Archaeplastida, believed to be monophyletic. We report the results of an analysis of the phylogeny of putative globins in the currently available genomes to bacterial and o...
supported by the National Natural Science Foundation of China (Grant Nos. 30830066 and 30771151);the National Basic Research Program (Grant No. 2005CB724600)
The eukaryotic genome contains varying numbers of non-coding RNA(ncRNA) genes."Computational RNomics" takes a multidisciplinary approach,like information science,to resolve the structure and function of ncRNAs.Here,we...
A glycosylphosphatidylinositol (GPI) anchor is a common but complex C-terminal post-translational modification of extracellular proteins in eukaryotes. Here we investigate the problem of correctly annotating GPI-anc...
This work was supported by the National Natural Science Foundation of China(No.30270752);the Guang-dong Natural Science Foundation(No.031616).
A database called eukaryotic intron database(EID)was developed based on the data from GenBank.Studies on the statistical characteristics of EID show that there were 103,848 genes,478,484 introns,and 582,332 exons,with...
This work was supported by the Hi-Tech Research and Development Program of China (863 Program) and the National Natural Science Foundation of China (No. 30300262).
Microsatellites or simple sequence repeats (SSRs) have been found in mostorganisms during the last decade. Since large-scale sequences are being generated, especially thosethat can be used to search for microsatellite...
Objective To construcl an eukaryote expression uector containing bone morphogenetic protein-2(BMP2)mature peptide,Methods Gene splicing by overlapping extension PCR(SOE-PCR)method was used to clone BMP2 signal peptide...
The nuclear matrix of diplomonad Giardia lamblia was detected for the first time with DGD embedmentsectioning- embedment free electron microscopy after a series of specific extractions. The result showed that archaezo...