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NUCLEOLUS: 作品数：44被引量：47H指数：4; 导出分析报告; 相关作者：郝水焦明大曾宪录刘辉段崇文更多>>; 相关机构：东北师范大学长春师范学院中国科学院北京大学更多>>; 相关期刊：《Science China(Life Sciences)》《Science China Chemistry》《Virologica Sinica》《World Journal of Hematology》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划中国博士后科学基金国家教育部博士点基金更多>>

The Triple Helix of innovation as a double game involving domestic and foreign actors: 《Journal of Data and Information Science》2024年第1期82-100,共19页Eustache Mêgnigbêto; Purpose:The collaboration relationships between innovation actors at a geographic level may be considered as grouping two separate layers,the domestic and the foreign.At the level of each layer,the relationships and t...; 关键词：Triple Helix Game theory Core Shapley value NUCLEOLUS South Korea West Africa

Probing mitochondrial damage using a fluorescent probe with mitochondria-to-nucleolus translocation被引量：1: 《Chinese Chemical Letters》2024年第1期352-356,共5页Chi Li Chong Zong Yang Liu Zhiqiang Liu Kang-Nan Wang Xiaoqiang Yu; the Shenzhen Science and Technology Research and Development Funds(No.JCYJ20190806155409104);National Natural Science Foundation of China(Nos.52150222,21672130 and 52073163);Guangdong Basic and Applied Basic Research Foundation(No.2019A1515110356);the Qilu Young Scholars Program of Shandong University.; Mitochondrial damage is closely related to the occurrence of many diseases.However,accurate monitoring and reporting of mitochondrial damage are not easy.Here,we developed a small molecule fluorescent probe named CB-C...; 关键词：Fluorescent probe Mitochondria targeting Nucleolus translocation Mitochondrial damage diagnosis Fluorescence imaging

Explore the nucleolus: unveiling the hidden layer with superresolution microscopy: 《Science China(Life Sciences)》2023年第9期2193-2195,共3页Rongfei Wei Xinyu Wang Dong Li; The nucleolus, a well-known membraneless organelle and the largest substructure with the highest transcriptional activity in the nucleus, was discovered over 200 years ago and is best known for its critical role in ri...; 关键词：TRANSCRIPTIONAL ORGANELLE resolution

In phase with the nucleolus: 《Cell Research》2023年第8期579-580,共2页Denis L.J.Lafontaine; The nucleolus is a biomolecular condensate responsible for ribosome biogenesis.Using super-resolution microscopy,the team of Ling-Ling Chen has identified a novel nucleolar subcompartment,ascribing to it a function in...; 关键词：PHASE STEPS SEPARATION

A Carbonized Fluorescent Nucleolus Probe Discloses RNA Reduction in the Process of Mitophagy: 《CCS Chemistry》2022年第8期2698-2710,共13页Hua Liu Xin Geng Xin Wang Lin Wei Zhaohui Li Shen Lin Lehui Xiao; from the National Natural Science Foundation of China(NSFC,Project No.22174079,21974073).; Mitophagy is a complicated process of cell metabolism that exhibits dynamic spatiotemporal coordination between multiple organelles.Despite its relevance to nucleoli,visualizing the distribution of nucleolar RNA in th...; 关键词：MITOPHAGY RNA nanoscopic imaging carbon dots BLINKING

Nucleolus localization of SpyCas9 affects its stability and interferes with host protein translation in mammalian cells: 《Genes & Diseases》2022年第3期731-740,共10页Renke Tan Wenhao Du Yiyang Liu Xiaoji Cong Meirong Bai Chenxiao Jiang Zengxia Li Minjia Tan Dengke K.Ma Qiang Huang Wei Jiang Yongjun Dang; This work was supported by the National Key Research and Development Program of China(No.2018YFC0310900);the National Natural Science Foundation of China grants(No.31270830,21572038,21877016 to Y.D,No.31671386 to Q.H,81972621 to W.J);the Development Fund for Shanghai Talents,Fund of State Key Laboratory of Bioorganic and Natural Products Chemistry,Fund of State Key Laboratory of Drug Research,Chinese Academy of Science(No.SIMM1601KF-08);Fudan University Graduate Student Research Grant.; The CRISPR/Cas9 system,originally derived from the prokaryotic adaptive immune system,has been developed as efficient genome editing tools.It enables precise gene manipulation on chromosomal DNA through the specific b...; 关键词：CRISPR/Cas9 Gene editing Global transcription Nucleolus detention signal TRANSLATION

The nucleolus as a genomic safe harbor for strong gene expression in Nannochloropsis oceanica被引量：1: 《Molecular Plant》2022年第2期340-353,共14页Christian Südfeld Ana Pozo-Rodríguez Sara A.Manjavacas Díez RenéH.Wijffels Maria J.Barbosa Sarah D'Adamo; part of the Dutch Research Council(NWO)Building Blocks of Lite programme(grant number 737.016.007).; Microalgae are used in food and feed,and they are considered a potential feedstock for sustainably pro-duced chemicals and biofuel.However,production of microalgal-derived chemicals is not yet economically feasible.Ge...; 关键词：NANNOCHLOROPSIS gene expression NUCLEOLUS RNA polymerase I IRES aIRES

Nucleolar GTPase Bms1 displaces Ttf1 from RFB-sites to balance progression of rDNA transcription and replication被引量：1: 《Journal of Molecular Cell Biology》2021年第12期902-917,共16页Yanqing Zhu Yong Wang Boxiang Tao Jinhua Han Hong Chen Qinfang Zhu Ling Huang Yinan He Jian Hong Yunqin Li Jun Chen Jun Huang Li Jan Lo Jinrong Peng; by the National Key R&D Program of China(2018YFA0800501);the National Natural Science Foundation of China(31771596 and 32000565).; 18S,5.8S,and 28S ribosomal RNAs(rRNAs)are cotranscribed as a pre-ribosomal RNA(pre-rRNA)from the rDNA by RNA polymerase I whose activity is vigorous during the S-phase,leading to a conflict with rDNA replication.This ...; 关键词：Bms1 cell cycle NUCLEOLUS ribosome small subunit processome replication-fork barrier Ttf1 zebrafish

Nucleolus-localized Def-CAPN3 protein degradation pathway and its role in cell cycle control and ribosome biogenesis被引量：2: 《Journal of Genetics and Genomics》2021年第11期955-960,共6页Shuyi Zhao Delai Huang Jinrong Peng; the National Key R&D Program of China and the Natural Science Foundation of China in the order of 2018YFA0800502,2017YFA0504501,31330050.; The nucleolus,as the‘nucleus of the nucleus’,is a prominent subcellular organelle in a eukaryocyte.The nucleolus serves as the centre for ribosome biogenesis,as well as an important site for cell-cycle regulation,ce...; 关键词：NUCLEOLUS Protein degradation Def CAPN3 P53 CHK1 Wee1 Mpp10 Sas10

Capn3 depletion causes Chk1 and Wee1 accumulation and disrupts synchronization of cell cycle reentry during liver regeneration after partial hepatectomy被引量：3: 《Cell Regeneration》2020年第1期74-91,共18页Feng Chen Delai Huang Hui Shi Ce Gao Yingchun Wang Jinrong Peng; This study was supported by the National Key R&D Program of China and the Natural Science Foundation of China in the order of 2018YFA0800502,31830113 and 2017YFA0504501.; Recovery of liver mass to a healthy liver donor by compensatory regeneration after partial hepatectomy(PH)is a prerequisite for liver transplantation.Synchronized cell cycle reentry of the existing hepatocytes after P...; 关键词：Def Capn3 CHK1 Wee1 NUCLEOLUS Cell cycle Liver regeneration Partial hepatectomy ZEBRAFISH

NUCLEOLUS