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This work was supported by the National Natural Science Foundation of China(81973424,82073966,82204346);the CAMS Innovation Fund for Medical Sciences(CIFMS)(Grant No.2021-I2M-1-029,China);the National Key R&D Program of China(2023YFC3504800);the Fundamental Research Funds for the Central public welfare research institutes(ZZ16-YQ-047,ZZ16-ND-10-02,China);the Key Scientific Research Foundation of the Higher Education Institutions of Anhui Province,China(KJ2021A0235).
Crocus sativus (saffron) is a globally autumn-flowering plant, and its stigmas are the most expensive spice and valuable herb medicine. Crocus specialized metabolites, crocins, are biosynthesized in distant species, G...
Objective:To study the therapeutic effect of crocin on diabetic retinopathy(DR)in rats based on toll-like receptor 4(TLR4)/myeloid differentiation factor 88(My D88)/nuclear factor-κB(NF-κB)pathway.Methods:Thirty SPF...
supported by National Medicinal Plant Board(NMPB),Dept.of Ayush,Government of India.(Project No.R&D/MS 04/2010).
Background:Carotenoids play important role in delay of aging process.Orange coloured tubular calyx of flowers of Nyctanthes arbor-tristis contains crocin,an apocarotenoid which forms a major component of stigma of saf...
The use of Crocin, derived from the flowers of Crocus sativus, is investigated as corrosion inhibitor for the AA1050, AA5083, AA5754 and AA6082 aluminum alloys in chloride ions environment. Aluminum and aluminum alloy...
We aimed to investigate whether carnosine(a natural dipeptide found in humans)and crocin(a natural product extracted from saffron and gardenia)can prevent the harmful effects of acute kidney injury(AKI)caused by glyce...
Medicinal plants are rich in nutrients and phytochemicals which prevent and treat a wide range of ailments.Accumulating experimental studies exhibit that some bioactive ingredients extracted from medicinal plants have...
Diabetes mellitus(DM)disease can affect process of apoptosis by increasing oxidative stress,nevertheless exercise and crocin can improve apoptosis;therefore present study aimed to investigate the effect of continued t...
[Objectives]To explore the protection mechanism of crocin against ischemia-reperfusion injury of myocardial cells.[Methods]Newborn male SD rats were selected,left ventricular cardiomyocytes(CMs)were isolated,and a hyp...
AIM:To study the effect of uncrosslinked and crosslinked hyaluronic acid combined with other artificial tear components in patients with dry eye caused by moderate meibomian gland dysfunction.METHODS:Prospective,singl...