CROCIN

作品数:21被引量:70H指数:5
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相关作者:赵培杨慧科李雪梅张珞陈龙邦更多>>
相关机构:重庆医科大学哈尔滨医科大学中国药科大学南京军区南京总医院更多>>
相关期刊:《Journal of Biomedical Research》《Neural Regeneration Research》《Open Journal of Applied Sciences》《Asian Pacific Journal of Tropical Biomedicine》更多>>
相关基金:国家高技术研究发展计划国家自然科学基金重庆市自然科学基金更多>>
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Crocus genome reveals the evolutionary origin of crocin biosynthesis被引量:1
《Acta Pharmaceutica Sinica B》2024年第4期1878-1891,共14页Zhichao Xu Shanshan Chen Yalin Wang Ya Tian Xiaotong Wang Tianyi Xin Zishan Li Xin Hua Shengnan Tan Wei Sun Xiangdong Pu Hui Yao Ranran Gao Jingyuan Song 
This work was supported by the National Natural Science Foundation of China(81973424,82073966,82204346);the CAMS Innovation Fund for Medical Sciences(CIFMS)(Grant No.2021-I2M-1-029,China);the National Key R&D Program of China(2023YFC3504800);the Fundamental Research Funds for the Central public welfare research institutes(ZZ16-YQ-047,ZZ16-ND-10-02,China);the Key Scientific Research Foundation of the Higher Education Institutions of Anhui Province,China(KJ2021A0235).
Crocus sativus (saffron) is a globally autumn-flowering plant, and its stigmas are the most expensive spice and valuable herb medicine. Crocus specialized metabolites, crocins, are biosynthesized in distant species, G...
关键词:Crocus sativus WGT Crocin biosynthesis Carotenoids APOCAROTENOIDS CCDS 
Therapeutic Effect of Crocin on Diabetic Retinopathy in Rats Based on TLR4/My D88/NF-κB Pathway
《Chinese Journal of Biomedical Engineering(English Edition)》2023年第2期86-92,共7页ZHANG Kai-ping CHEN Wan-ling ZHANG Qiu-xia WU Sen 
Objective:To study the therapeutic effect of crocin on diabetic retinopathy(DR)in rats based on toll-like receptor 4(TLR4)/myeloid differentiation factor 88(My D88)/nuclear factor-κB(NF-κB)pathway.Methods:Thirty SPF...
关键词:diabetic retinopathy CROCIN toll-like receptor 4(TLR4) myeloid differentiation factor 88(MyD88) nuclear transcription factor-κB(NF-κB) 
Formulation Containing Phytosomes of Carotenoids from Nyctanthes arbor-tristis and Tagetes patula Protect D-galactose Induced Skin Aging in Mice
《Clinical Complementary Medicine and Pharmacology》2023年第1期35-46,共12页Archana Arvind Naik Chhaya Harihar Gadgoli Arvind Bhimrao Naik 
supported by National Medicinal Plant Board(NMPB),Dept.of Ayush,Government of India.(Project No.R&D/MS 04/2010).
Background:Carotenoids play important role in delay of aging process.Orange coloured tubular calyx of flowers of Nyctanthes arbor-tristis contains crocin,an apocarotenoid which forms a major component of stigma of saf...
关键词:AGING CROCIN Phytosomes Nyctanthes arbor-tristis Collagen Elastin Galactose induced aging 
Experimental Investigation of Inhibition Efficiency of Crocin for Chloride-Induced Corrosion of Aluminum Alloys
《Open Journal of Applied Sciences》2022年第11期1931-1943,共13页Paraskevi Pantazopoulou Stamatina Theohari Sofia Kalogeropoulou 
The use of Crocin, derived from the flowers of Crocus sativus, is investigated as corrosion inhibitor for the AA1050, AA5083, AA5754 and AA6082 aluminum alloys in chloride ions environment. Aluminum and aluminum alloy...
关键词:CROCIN Aluminum Corrosion Eco-Friendly Inhibitors Sodium Chloride Environment Electrochemical and Gravimetric Methods 
Carnosine and crocin ameliorate oxidative stress in rats with rhabdomyolysis-induced acute kidney injury through upregulating HO-1 gene expression
《Food Bioscience》2022年第5期904-914,共11页Nahla E.El-Ashmawy Eman G.Khedr Ahmed S.Doghish Mohammed S.Elballal 
We aimed to investigate whether carnosine(a natural dipeptide found in humans)and crocin(a natural product extracted from saffron and gardenia)can prevent the harmful effects of acute kidney injury(AKI)caused by glyce...
关键词:CARNOSINE CROCIN Acute kidney injury RHABDOMYOLYSIS ANTIOXIDANT 
Hepato-and reno-protective effects of thymoquinone,crocin,and carvacrol:A comprehensive review被引量:1
《Asian Pacific Journal of Tropical Biomedicine》2022年第5期185-196,共12页Akbar Anaeigoudari 
Medicinal plants are rich in nutrients and phytochemicals which prevent and treat a wide range of ailments.Accumulating experimental studies exhibit that some bioactive ingredients extracted from medicinal plants have...
关键词:CARVACROL CROCIN THYMOQUINONE HEPATOPROTECTIVE Reno-protective INFLAMMATORY Oxidative stress NF-κB Nrf2 
高糖条件下crocin对血管内皮线粒体膜电位及ROS产生的影响
《解剖学杂志》2021年第S01期212-212,共1页杨慧科 李超 王罗丹 吴庆 李雪梅 张雅芳 
藏红花素(crocin)具有抗氧化和保护心血管的作用。本研究通过高血糖培养内皮细胞,诱导产生过量活性氧(ROS),应用crocin干预后探讨其对ROS生成的影响及作用机制。结果发现,crocin能有效降低高糖诱导ROS的过量产生,提高谷胱甘肽过氧化物酶...
关键词:NADPH氧化酶 线粒体膜电位 超氧化物歧化酶 藏红花素 血管内皮 ROS 影响及作用 
The Effect of Continued Training with Crocin on Apoptosis Markers in Liver Tissue of High Fat Diet Induced Diabetic Rats
《Molecular & Cellular Biomechanics》2020年第4期155-163,共9页Zahra Alimanesh Zeynab Alimanesh Fatemeh Davari Saeedeh Shadmehri Mozhgan Ahmadi Seyed Ali Hosseini Sepideh Dolati Alemeh Hariri Far 
Diabetes mellitus(DM)disease can affect process of apoptosis by increasing oxidative stress,nevertheless exercise and crocin can improve apoptosis;therefore present study aimed to investigate the effect of continued t...
关键词:EXERCISE CROCIN APOPTOSIS DIABETES TISSUE 
Effects of Crocin on Nox2 Expression and ROS Level of Hypoxia/Reoxygenation-induced Injury of Cardiomyocytes被引量:2
《Medicinal Plant》2020年第5期71-75,共5页Chao ZENG Yongji XING Lizhi BAO Yuanyuan WANG Weiqing HU Jun WU Xiaohong LIU Nengwu WEN Jiping FAN 
[Objectives]To explore the protection mechanism of crocin against ischemia-reperfusion injury of myocardial cells.[Methods]Newborn male SD rats were selected,left ventricular cardiomyocytes(CMs)were isolated,and a hyp...
关键词:CROCIN Cardiomyocytes(CMs) Hypoxia/reoxygenation injury Oxidative stress 
Crosslinked hyaluronic acid with liposomes and crocin for management symptoms of dry eye disease caused by moderate meibomian gland dysfunction被引量:5
《International Journal of Ophthalmology(English edition)》2020年第9期1368-1373,共6页José-María Sánchez-González Concepción De-Hita-Cantalejo María Carmen Sánchez-González 
AIM:To study the effect of uncrosslinked and crosslinked hyaluronic acid combined with other artificial tear components in patients with dry eye caused by moderate meibomian gland dysfunction.METHODS:Prospective,singl...
关键词:LIPOSOME crosslinked hyaluronic acid meibomian gland dysfunction contact lens dry eye disease 
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