Supported by the National Key Research and Development Program of China(grant number 2021YFC2301000);the National Natural Science Foundation of China(NSFC)(grant number 81973106).
What is already known about this topic?Pertussis has reemerged as a significant public health threat,primarily due to variations in Bordetella pertussis strains,antimicrobial resistance,and vaccine evasion.What is add...
financially supported by the National Key Research Development Program of China(2022YFC2105403);the Taishan Scholars Program,the Shanghai Pilot Program for Basic Research(22TQ1400100-14);the Natural Science Foundation of Shanghai(23ZR1416500);the Frontiers Science Center for Materiobiology and Dynamic Chemistry(JKVJ1231036).
Comparative transcriptomics uncovered distinct expression patterns of genes associated with cofactor and vitamin metabolism in the high-yielding mutant strain Saccharopolyspora erythraea HL3168 E3,as compared to the w...
supported by the National Natural Science Foundation of China (No. 42101077);The Key Research and Development Program of Shaan Xi Province (No. 2020SF-387);ShaanXi Thousand Talent Program for Young Outstanding Scientists (No. 334041900007)
A recent study showed that erythromycin(ERY)exposure caused hormesis in a model alga(Raphidocelis subcapitata)where the growth was promoted at an environmentally realistic concentration(4μg/L)but inhibited at two hig...
This study was funded by the National Key R&D Program of China[2019YFA0110600]and National Natural Science Foundation of China [81970916, 81671031].
Erythromycin is a commonly used broad-spectrum antibiotic,but resistance to this antibiotic makes its use less effective.Considerable efforts,beside finding alternatives,are needed to enhance its antimicrobial effect ...
BACKGROUND Respiratory infections in children are common pediatric diseases caused by pathogens that invade the respiratory system.Children are considerably susceptible to Mycoplasma pneumoniae infection.There has bee...
Antibiotic macrolides are experiencing renewed interest in anti-infective therapy since the advent of ketolides. This therapeutic class was introduced in order to broaden the narrow antibacterial spectrum of macrolide...
This work was supported by the Biotechnology and Biological Sciences Research Council project grant BB/K003356/1.HPLC-MS analysis was performed on equipment within the Centre of Excellence in Mass Spectrometry(University of York),funded by Science City York(Yorkshire Forward,EP/K039660/1,EP/M028127/1).
Serine integrases have been shown to be efficient tools for metabolic pathway assembly.To further improve the flexibility and efficiency of pathway engineering via serine integrases,we explored how multiple orthogonal...
BACKGROUNDG roup B Streptococcus agalactiae (GBS) is the main etiologic agent associated withearly-onset neonatal sepsis, and of all newborns of parturients colonized by GBS,approximately 1%-2% develop invasive, early...
the National Research Council of Thailand(NRCT)for providing a research grant.
Objective:To evaluate the synergistic effect ofα-mangostin with tetracycline,erythromycin,and clindamycin against bacteria involved in acne production.Methods:A broth microdilution method was used to determine the mi...
An important problem in management of the case with myasthenia gravis (MG) is the control of exacerbation. There are several possible causes of exacerbation of MG including the use of drug. Here, the authors report a ...