云南高校图书馆联盟文献共享服务平台- HYDROXYCAMPTOTHECIN

HYDROXYCAMPTOTHECIN: 作品数：20被引量：120H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：马梅芳于涛杨磊史伟国祖元刚更多>>; 相关机构：东北林业大学浙江省立同德医院复旦大学中国药科大学更多>>; 相关期刊：《中国药理通讯》《胃肠病学》《Journal of Forestry Research》《Acta Biochimica et Biophysica Sinica》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金更多>>

Ferrocene conjugated glutathione consumption for enhanced ferroptosis therapy and chemotherapy: 《Nano Research》2025年第4期364-374,共11页Limei Zhang Huatai Zhu Yuting Ren Peng Ye Jiandu Lei; supported by the Fundamental Research Funds for the Central Universities(No.PTYX202449).; As the backbone of tumor therapy,chemotherapy is prone to tumor resistance due to its apoptotic pathway.Ferroptosis,as an effective form of non-apoptotic cell death,can overcome chemotherapy apoptosis-induced resistan...; 关键词：ferroptosis glutathione consumption ferrocene(Fc) honokiol(HNK) hydroxycamptothecin(HCPT)

Mechanism of apoptotic induction on T24 cells by honokiol and its synergistic anticancer effect in combination with hydroxycamptothecin被引量：2: 《Journal of Traditional Chinese Medicine》2021年第4期515-522,共8页LOU Guoguang LUO Yiting XIE Liping YAO Hangping HU Qing; Supported by the Scientific Research Project of Zhejiang Provincial Health Committee:the Mechanism of Apoptotic Induction of Honokiol on T24 Bladder Cancer Cells and its Synergistic Anticancer Effect with Hydroxycamptothecin(No.2016YB089);the Project of Science and Technology of Traditional Chinese Medicine in Zhejiang Province:Study on Comprehensive Therapy for Radiocystitis by Alum Intravesical Instillation in Combination with Hyperbaric Oxygen and Rhodiola Decoction(No.2018ZA064)。; OBJECTIVE:To investigate the mechanism of honokiol(HNK)on bladder cancer cells and its synergistic anticancer effect with hydroxycamptothecin(HCPT).METHODS:Control,HNK,HCPT,and HNK plus HCPT groups were established.Th...; 关键词：urinary bladder neoplasms apoptosis PHOSPHORYLATION NF-kappa B HONOKIOL

A ROS-Stimulus-Responsive Nanocarrier Loading with Guanidine-Modified Hydroxycamptothecin Prodrug for Enhanced Anti-Tumor Efficacy被引量：2: 《CCS Chemistry》2020年第5期305-316,共12页Zhilin Liu Haiyang Yu Na Shen Zhaohui Tang Xuesi Chen; support for this work was provided by the Ministry of Science and Technology of China(no.2018ZX09711003-012);National Natural Science Foundation of China(Project nos.51503202,51673189,51873206,51833010,and 51520105004).; We report a reactive oxygen species(ROS)-stimulus-responsive phenylboronic acid pinacol ester nanocarrier,loaded with guanidine-modified 10-hydroxycamptothecin(HCPT)prodrug,to create a drug delivery-base nanomedicine....; 关键词：ROS NANOMEDICINE cancer therapy PRODRUG NANOCARRIER

Polymer Delivery of Hydroxycamptothecin against C6 Glioma: 《Journal of Cancer Therapy》2014年第10期920-928,共9页Jing Hu Huafei Tang Songqing Liu; Hydroxycamptothecin is a potent antineoplastic agent that has shown efficacy against multiple tumor lines in vitro. This is the first study to investigate the release, distribution, and efficacy of hydroxycamptothecin...; 关键词：HYDROXYCAMPTOTHECIN Polylactic ACID (PLA) C6 GLIOMA SUSTAINED Release

Genome-wide analysis of microRNA and mRNA expression signatures in hydroxycamptothecinresistant gastric cancer cells被引量：15: 《Acta Pharmacologica Sinica》2011年第2期259-269,共11页Xue-mei WU Xiang-qiang SHAO Xian-xin MENG Xiao-na ZHANG LiZHU Shi-xu LIU Jian LIN Hua-sheng XIAO; Aim： To investigate the involvement of microRNAs （miRNAs） in intrinsic drug resistance to hydroxycamptothecin （HCPT） of six gastric cancer cell lines （BGC-823, SGC-7901, MGC-803, HGC-27, NCI-N87, and AGS）. Meth...; 关键词：hydroxycamptothecin （HCPT） gastric cancer MICRORNA signature drug resistance gene expression regulation cluster analysis messenger RNA

Pilot study of intravesical instillation of two new generation anthracycline antibiotics in prevention of superficial bladder cancer recurrence被引量：23: 《Chinese Medical Journal》2010年第23期3422-3426,共5页CHEN Si-yang DU Lin-dong ZHANG Yu-hai; Background Superficial bladder cancer accounts for 60%-70% of all bladder cancer cases in China, when treatment consists of only transurethral resection of the bladder tumor （TUR-BT）, recurrence and progresses in th...; 关键词：EPIRUBICIN PIRARUBICIN HYDROXYCAMPTOTHECIN superficial bladder cancer intravesical instillation

Homogenate extraction technology of camptothecine and hydroxycamptothecin from Camptotheca acuminata leaves: 《Journal of Forestry Research》2009年第A2期168-170,共3页SHI Wei-guo, ZU Yuan-gang, ZHAO Chun-jian, YANG Lei Key Laboratory of Forest Plant Ecology of Ministry of Education, Northeast Forestry University, Harbin 150040, P.R.China; supported by National Key Tech-nology R & D Program (grant no. 2006BAD18B04).; Camptothecine(CPT) and hydroxycamptothecin(HCPT), two kinds of anti-cancer alkaloids, were extracted from Camptotheca acuminata leaves using homogenate extraction technology under different conditions such as the rati...; 关键词：HOMOGENATE Camptotheca acuminata leaves camptothecine HYDROXYCAMPTOTHECIN

Preparation and Cytotoxic activity of Hydroxycamptothecin Nanosuspensions: 《中国药理通讯》2009年第2期73-73,共1页Wei-Jing Liu Yong-Xing Zhao Hai-Ying Hua; 关键词：细胞药物治疗方法活性羟基喜树碱纳米颗粒

Homogenate extraction technology of camptothecine and hydroxycamptothecin from Camptotheca acuminata leaves被引量：2: 《Journal of Forestry Research》2009年第2期168-170,I0004,共4页史伟国祖元刚赵春建杨磊; Camptothecine （CPT） and hydroxycamptothecin （HCPT）, two kinds of anti-cancer alkaloids, were extracted from Camptotheca acuminata leaves using homogenate extraction technology under different conditions such as th...; 关键词：HOMOGENATE Camptotheca acuminata leaves camptothecine HYDROXYCAMPTOTHECIN

Clinical analysis of HCPT plus FOLFOX4 regimen as salvage therapy for patients with advanced gastric cancer: 《The Chinese-German Journal of Clinical Oncology》2008年第12期698-700,共3页Xiaoqiang Fan Xijian Zhou Xiangyong Li Xinyu Tang Rengui Zhou Dejian Pan; Objective: To evaluate the therapeutic as well as side effects of hydroxycamptothecin (HCPT) plus FOLFOX4 regimen as salvage therapy for patients with advanced gastric cancer. Methods: A total of 19 patients with adva...; 关键词：hydroxycamptothecin （HCPT） FOLFOX4 salvage therapy advanced gastric cancer

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