PROCOLLAGEN

作品数:34被引量:274H指数:9
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相关领域:医药卫生更多>>
相关作者:金哲虎南美兰金承龙张季郝敏更多>>
相关机构:延边大学医学院附属医院上海上药华宇药业有限公司南京中医药大学更多>>
相关期刊:《Hepatobiliary & Pancreatic Diseases International》《Chinese Medical Journal》《实用医学杂志》《Journal of Biosciences and Medicines》更多>>
相关基金:国家自然科学基金中国博士后科学基金江苏省高校自然科学研究项目国家中医药管理局度中医药行业科研专项更多>>
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Colchicine reduces procollagen Ⅲ and increases pseudocholinesterase in chronic liver disease被引量:14
《World Journal of Gastroenterology》2010年第23期2889-2894,共6页Sergio Muntoni Marcos Rojkind Sandro Muntoni 
AIM:To test whether colchicine would be an effective antif ibrotic agent for treatment of chronic liver diseases in patients who could not be treated with α-interferon.METHODS:Seventy-four patients(46 males,28 female...
关键词:Chronic liver disease COLCHICINE Liver cirrhosis Liver fibrosis Type  procollagen peptide 
Effect of Astragalus complanatus flavonoid on anti-liver fibrosis in rats被引量:8
《World Journal of Gastroenterology》2005年第37期5782-5786,共5页Chun-Yu Liu Zhen-Lun Gu Wen-Xuan Zhou Ci-Yi Guo 
AIM: To observe the anti-liver fibrosis effect of Astragalus complanatus fiavonoids (ACF) in rats. METHODS: The liver fibrosis model in rats was established by injecting interperitoneally 0.2 mL/100 g 0.5% dimethy...
关键词:Astragalus complanatus  Liver fibrosis N-propeptide of typeⅠ procollagen N-propeptide of type  procollagen Malondialdehyde Superoxide dismutase Matrix metal protease-1 Tissue inhibitor of metal protease-1 
Leptin administration exacerbates thioacetamide-induced liver fibrosis in mice被引量:9
《World Journal of Gastroenterology》2005年第31期4822-4826,共5页Kai Dai Jun-Ying Qi De-Ying Tian 
AIM: To investigate the effects of leptin administration on liver fibrosis induced by thioacetamide (TAA). METHODS: Twenty-four male C57BI/6 mice were randomly allocated into four groups, which were intra-peritone...
关键词:Liver fibrosis LEPTIN α1(I) procollagen 
Effects of adrenomedullin gene overexpression on biological behavior of hepatic stellate cells被引量:3
《World Journal of Gastroenterology》2005年第23期3549-3553,共5页YiWang Jin-ShengZhang Guang-CunHuang QiCheng Zhong-HuaZhao 
Supported by the National Natural Scientific Foundation of China,No.30170417
AIM: To investigate the effects of adrenomedullin (AM) gene overexpression on the biological characteristics of human hepatic stellate cells (hHSCs) by stable transfection.METHODS: hHSCs which express low basal levels...
关键词:ADRENOMEDULLIN Hepatic stellate cell Procollagen type  and  
Elevated serum values of procollagen Ⅲ peptide (PIIIP)in patients with ulcerative colitis who will develop pseudopolyps被引量:2
《World Journal of Gastroenterology》2003年第3期619-621,共3页■arko Babi Vjekoslav Jagi Zvonko Petrovi Ante Bili KapetanoviDinko Goranka Kubat Rosana Troskot Mira Vukeli 
AIM: To assess the impact of procollagen Ⅲ peptide as a marker of collagenesis in the development of pseudopolyps in patients with ulcerative colitis.METHODS: Development of pseudopolyps was monitored in 25 patients ...
关键词:原骨胶原Ⅲ 溃疡性大肠炎 血清学检查 假性大肠息肉 作用机制 
Inhibiting effect of antisense oligonucleotides phosphorthioate on gene expression of TIMP-1 in rat liver fibrosis被引量:73
《World Journal of Gastroenterology》2001年第3期363-369,共7页Qing He Nie Yong Qian Cheng Yu Mei Xie Yong Xing Zhou Yi Zhan Cao The Center of Infectious Disease Diagnosis and Treatment of PLA,Tangdu Hospital,Forth Military Medical University,Xi’an 710038,Shaanxi Province,ChinaDr,Qing He Nie graduated from Qinghai Medical College as a doctor in 1983,got master degree at Beijing 302 Army Hospital in 1993,got doctor degree at the Third Military Medical University in 1998,engaged in postdoctoral research at the Fourth Military Medical University from 1998 to 2000,now an associate professor,specialized in clinical and experimental research of infectious diseases,had more than 90 papers published,coauthor of ten books,first author of one book. 
Supported by the Postdoctoral Science Foundation of China(No.1999-10 State Postdoctoral Foundation Commission)
AIM: To observe the inhibition of antisense oligonucleotides (asON) phosphorthioate to the tissue inhibitors metalloproteinase-1 (TIMP-1) gene and protein expression in the liver tissue of immunologically induced hepa...
关键词:Gene Therapy Animals Collagen Type I Collagen Type III Disease Models  Animal Female Gene Expression Hepatocytes Immunohistochemistry Liver Liver Cirrhosis Microscopy  Electron Oligonucleotides  Antisense PROCOLLAGEN RNA  Messenger RATS Rats  Wistar Research Support  Non-U.S. Gov't Tissue Inhibitor of Metalloproteinase-1 
Effects of glycyrrhetinic acid on collagen metabolism of hepatic stellate cells at different stages of liver fibrosis in rats被引量:29
《World Journal of Gastroenterology》2001年第1期115-119,共5页Ji Yao Wang Qi Sheng Zhang Ji Sheng Guo Mei Yu Hu Department of Gastroenterology, Zhongshan Hospital, Medical Center, Fu Dan University Shanghai Medical University), Shanghai 200032, China 
Project supported by the National Natural Science Foundation of China, No. 39500138
INTRODUCTIONLiver fibrosis is a dynamic course leading tocirrhosis from a various chronic liver diseases. Thepathological basis of fibrosis is the disturbance ofproduction and degradation of the extracellularmatrix (E...
关键词:Administration  Topical Animals Anti-Inflammatory Agents Carbon Tetrachloride Cell Division Collagen Type I Collagen Type III COLLAGENASES Disease Models  Animal Gene Expression Glycyrrhetinic Acid Liver Cirrhosis Plasmids PROCOLLAGEN PROLINE RNA  Messenger RATS Rats  Sprague-Dawley Research Support  Non-U.S. Gov't THYMIDINE Tritium 
Dynamic changes of typeⅠ,Ⅲand N collagen synthesis and distribution of collagen-producing cells in carbon tetrachloride-induced rat liver fibrosis被引量:47
《World Journal of Gastroenterology》1999年第5期397-403,共7页DU Wei-Dong ZHANG Yue-E ZHAl Wei-Rong and ZHOU Xiao-Mei(Department of Pathology, Shanghai Medical University, Shanghai200032, China)(National Laboratory for Oncogenes and Related Genes, ShanghaiCencer Institute)See invited commentary on page 388 
supported by National Natural Science Foundation of China(No.3933140);Shanghai Municipal Education Commission(No.980802).
AIM To find out the relationship between the gene transcription of different types ofprocollagen and the deposition of the relevant collagens in the liver tissue and to confirm the types of collagen producing cells in...
关键词:PROCOLLAGEN mRNA immunohistochemistry Northern blot analysis in SITU hybridization liver FIBROSIS 
Effects of Fuzheng Huayu 319 recipe on liver fibrosis in chronic hepatitis B被引量:7
《World Journal of Gastroenterology》1998年第4期76-81,共6页LIU Ping LIU Cheng XU Lie-Ming Hu Yi-Yang XUE Hui-Ming LIU Cheng-Hai ZHANG Zhi-Qing 
国家科学研究项目。
AIM To investigate clinic effects of Fuzheng Huayu 319 recipe (319 recipe) on liver fibrosis in chronic hepatitis B.METHODS Ninety-five patients with chronic hepatitis B were divide into the treated (63 cases) and con...
关键词:liver cirrhosis/therapy hepatitis B Fuzheng Huayu PROCOLLAGEN hyaluronic acid METALLOPROTEINASES HYDROXYPROLINE 
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