METALLOPROTEINASES

作品数:67被引量:127H指数:6
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相关领域:医药卫生生物学更多>>
相关作者:李源张丽英郭晓峰汪欣祝威更多>>
相关机构:中山大学附属第三医院泸州医学院附属医院白城市医院吉林大学第一医院更多>>
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相关基金:国家自然科学基金中国博士后科学基金陕西省卫生厅科学研究基金四川省应用基础研究计划项目更多>>
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Development of a novel HER2-CAR monocyte cell therapy with controllable proliferation and enhanced anti-tumor efficacy被引量:1
《Chinese Medical Journal》2024年第21期2590-2602,共13页Bing Yang Xiaoxue Wang Xundong Wei Jie Ma 
supported by the National High-Level Hospital Clinical Research Funding(No.BJ-2022-118);CAMS Innovation Fund for Medical Sciences(No.2021-1-I2M-050);National Natural Science Foundation of China(Nos.52273281 and 82173109);Guangxi Science and Technology Base and Talent Special Projects(No.AD21220001).
Background:One of the significant challenges for cell therapies,such as chimeric antigen receptor(CAR)-T cell therapy,is the poor infiltration of immune cells into tumor tissues.CAR-monocytes/macrophages(CAR-M)are pro...
关键词:Receptors chimeric antigen Macrophages MONOCYTES Cell suicide Antibody-dependent cell phagocytosis METALLOPROTEINASES 
Metalloproteinase expression after desflurane preconditioning in hepatectomies:A randomized clinical trial被引量:5
《World Journal of Hepatology》2020年第11期1098-1114,共17页Eleni Koraki Ioannis Mantzoros Christos Chatzakis Anna Gkiouliava Angeliki Cheva Athina Lavrentieva Freideriki Sifaki Helena Argiriadou Isaak Kesisoglou Konstantinos Galanos-Demiris Stefanos Bitsianis Konstantinos Tsalis 
BACKGROUND Hepatectomy with inflow occlusion results in ischemia-reperfusion injury;however,pharmacological preconditioning can prevent such injury and optimize the postoperative recovery of hepatectomized patients.Th...
关键词:DESFLURANE PRECONDITIONING HEPATECTOMY INFLAMMATION METALLOPROTEINASES Reperfusion injury 
Botulinum Toxin Type A and Its Possible Mechanisms on Wound Healing
《Modern Plastic Surgery》2020年第3期38-55,共18页Khushboo Gurung Qian Tan Ye Xu Bingchen Duan 
Botulinum toxin type-A (BTX-A), a subtype from known seven types of botulinum neurotoxin (serotype A-G), is produced by a gram-positive bacterium, Clostridium botulinum. The toxin is now widely and efficiently ...
关键词:Wound Healing Botulinum Toxin Type-A Hypertrophic Scar KELOID FIBROBLAST MYOFIBROBLASTS Transforming Growth Factor β-1 Collagen METALLOPROTEINASES Connective Tissue Growth Factor 
Effect of Endostar combined with Paclitaxel on the proliferation and migration of metalloproteinases and tumor cells in NSCLC patients被引量:1
《Journal of Hainan Medical University》2019年第19期48-52,共5页Qi Yong-Jian Zeng Xue-Hua Lai Ju-Ju Zha Wang-Jian 
Science and Technology Project of Jiangsu Provincial Hospital of Traditional Chinese Medicine (Y14066)
Objective: To explore the effect of endostar combined with taxol on tumor markers, vascular endothelial growth factor, neuron-specific enolase, metalloproteinase and tumor cell proliferation and migration in NSCLC pat...
关键词:ENDOSTAR PACLITAXEL NSCLC Metalloproteinase Proliferation and migration 
Antioxidant Mechanism of Xiaojin Pill(小金丸) for Treatment of Peyronie’s Disease in Rats Based on Matrix Metalloproteinases被引量:1
《Chinese Journal of Integrative Medicine》2019年第9期671-676,共6页GENG Qiang WANG Fu HAN Qiang CHEN Shao-feng OUYANG Bin LI Zhong ZHAO Yu GAO Qing-he YU Guo-jin GUO Jun 
Supported by the China Postdoctoral Science Foundation(No.178641)
Objective: To evaluate the effects of Xiaojin Pill(小金丸) in the treatment of Peyronie’s disease(PD) in a rat model. Methods: Twenty-four male Sprague-Dawley rats were randomly divided into four groups with 6 in eac...
关键词:antioxidant mechanism Xiaojin PILL Chinese medicine Peyronie’s DISEASE RATS matrix METALLOPROTEINASES 
Protective Effect of GRK2 and Effect of Sanguis Draconis Flavones on Focal Cerebral Ischemia-Reperfusion Injury in Rats
《Medicinal Plant》2019年第4期44-48,50,共6页Rui LI Huiyu JIA Deyun JIA Min SI Dewu JIA 
Supported by Foundation of Anhui Academy of Medical Sciences(YKY2018006)
[Objectives] To explore the protective effect of Sanguis Draconis flavones (SDF) on rat focal cerebral ischemia-reperfusion injury (CIRI) models established by middle cerebral artery occlusion (MCAO).[Methods] A total...
关键词:Sanguis DRACONIS flavones Cerebral ISCHEMIA-REPERFUSION injury G protein-coupled receptor kinase 2 Blood-brain barrier Matrix METALLOPROTEINASES 
Wulong Xiaozheng Wan medicated serum inhibits epithelial-mesenchymal transition in human gastric carcinoma cell line BGC823 by modulation of transforming growth factor-β1/Smad signaling被引量:3
《Journal of Traditional Chinese Medicine》2019年第3期380-392,共13页Zhang Yali Wang Bingyu Guo Xueying Yang Lei Li Dandan Yuan Xingxing 
Supported by State Administration of Traditional Chinese Medicine Science and Technology Research Projects(Chinese pharmaceutical 2016ZX05);Effect of Wulong Xiaozheng Wan on Intermediate Gastric Carcinoma and its Mechanism
OBJECTIVE:To evaluate the effect of Wulong Xiaozheng Wan medicated serum on the epithelial-mesenchymal transition (EMT) of BGC823 cell induced by transforming growth factor-β,(TGF-β,) and to explore its mechanism.ME...
关键词:Transforming growth factor BETA1 Smad proteins Signal transduction Epithelial-mesenchymal transition Matrix metalloproteinases secreted BGC823 cell WULONG Xiaozheng WAN 
The Influence of <i>Morinda citrifolia</i>(Noni) Fruit Juice on Collagen Deposition in the Skin: A Minireview
《Journal of Biosciences and Medicines》2018年第9期1-10,共10页Brett J. West 
The fruit of Morinda citrifolia, commonly known as noni, has an extensive history of use as a food and medicine throughout the tropics. Among its many uses, noni was believed to promote skin health. In vivo wound heal...
关键词:MORINDA citrifolia NONI Collagen FIBROBLAST Matrix METALLOPROTEINASES 
Diagnostic Value of Fecal Calprotectin and Serum MMP-9 in Diagnosing Disease Activity of Ulcerative Colitis
《Open Journal of Gastroenterology》2018年第6期234-244,共11页Ali Ghweil Ashraf Khodeary Shereen Philip Aziz 
Background and Study Aim: Ulcerative colitis (UC) is a chronic, idiopathic inflammatory bowel disease characterized by remission of disease activity. Searching for laboratory markers which are simple, sensitive, speci...
关键词:Inflammatory BOWEL Disease (IBD) ULCERATIVE COLITIS (UC) Matrix METALLOPROTEINASES (MMPs) FECAL CALPROTECTIN (FC) 
Activity of metalloproteinases and adiponectin in obese patients——a possible factor of incisional hernias after bariatric procedures
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2018年第1期65-70,共6页Wojciech SZCZESNY Magdalena KULIGOWSKA-PRUSINSKA Stanislaw DABROWIECKI Jakub SZMYTKOWSKI Adrian RESLINSKI Maciej SLUPSKI 
Purpose: Metalloproteinases are a key component of the pathogenesis of abdominal hernias. Obesity is considered a risk factor in herniogenesis and hernia recurrence. The aim of this study was to evaluate the serum co...
关键词:METALLOPROTEINASE ADIPONECTIN OBESITY Incisional hernia 
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