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作品数:559被引量:1196H指数:16
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相关作者:许清海胡亚楠李阳李洁张生瑞更多>>
相关机构:河北师范大学中国科学院北京大学复旦大学更多>>
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Comparative metabolomics reveal histamine biodegradation mechanism by salt stressed Bacillus subtilis JZXJ-7
《Food Science and Human Wellness》2025年第3期925-940,共16页Rundong Wang Yijia Deng Yuhao Zhang Xuepeng Li Ravi Gooneratne Jianrong Li 
supported by the National Key R&D Program of China(2019YFD0901702);National Natural Science Foundation of China(32201929,32202134);2025 Guangdong Basic and Applied Basic Research Foundation of Natural Science Foundation Project(2025A1515011748);High-level Talent Project of Lingnan Normal University(ZL2415);China Postdoctoral Science Foundation(2022M712625);2021 and 2022 Chongqing Postdoctoral Special Funding Project。
Bacillus subtilis JZXJ-7 isolated from shrimp paste can significantly degrade histamine under salt stress but the mechanism is unclear.This study aims to evaluate the effect of 170 and 340 mmol/L Na Cl on B.subtilis J...
关键词:Bacillus subtilis JZXJ-7 HISTAMINE Salt stress Antioxidant enzymes Metabolomics 
Single-nucleus RNA sequencing and spatial transcriptomics reveal the mechanism by which Xiaozhiling injection treats internal hemorrhoids
《World Journal of Gastrointestinal Surgery》2025年第4期333-346,共14页Min-Hui Ke Shu-Yan Huang Wei-Gan Lin Zhen-Guo Xu Xia-Xia Zheng Xian-Bao Liu You-Min Cheng Zuan-Fang Li 
Supported by the National Natural Science Foundation of China,No.81774118;the Foreign Cooperation Project of Science and Technology Department of Fujian Province,No.2023I0021;the Medical Innovation Project of Fujian Province,No.2024CXB013.
BACKGROUND Hemorrhoids,a prevalent chronic condition globally,significantly impact patients'quality of life.While various surgical interventions,such as external stripping and internal ligation,procedure for prolapse ...
关键词:Internal hemorrhoids Xiaozhiling injection FIBROBLAST Marker gene Single-cell sequencing Spatial transcriptome sequencing 
Multi-time point transcriptomics and metabolomics reveal key transcription and metabolic features of hepatic ischemia-reperfusion injury in mice
《Genes & Diseases》2025年第2期288-303,共16页Qi Li Xiaoyan Qin Liangxu Wang Dingheng Hu Rui Liao Huarong Yu Zhongjun Wu Yanyao Liu 
funded by the National Natural Science Foundation of China (No.82300745 to Yanyao Liu);China Postdoctoral Science Foundation (No.2023M730442 to Yanyao Liu);Chongqing Postdoctoral Science Foundation of China (No.CSTB2023NSCQ-BHX1003 to Yanyao Liu);Postdoctoral Cultivation Project of the First Affiliated Hospital of Chongqing Medical University (No.CYYY-BSHPYXM-202301 to Yanyao Liu);Chongqing Postdoctoral Innovation Talents Support Program (Chongqing,China) (No.2309013437264551 to Yanyao Liu)。
Hepatic ischemia-reperfusion injury is an unavoidable surgical complication of liver transplantation and the leading cause of poor graft function and increased mortality post-transplantation.Multiple mechanisms have b...
关键词:INFLAMMATION Liver ischemia-reperfusion injury Metabolic remodeling Metabolomics TRANSCRIPTOMICS 
Reveal short range interactions between u/d quarks in the NN,D_(03),and D_(30)systems
《Science China(Physics,Mechanics & Astronomy)》2025年第3期102-111,共10页Qi-Fang Lü Yu-Bing Dong Peng-Nian Shen Zong-Ye Zhang 
supported by the National Natural Science Foundation of China(Grant No.12375142);the Natural Science Foundation of Hunan Province(Grant No.2023JJ40421);the Key Project of Hunan Provincial Education Department(Grant No.21A0039);the Youth Talent Support Program of Hunan Normal University(Grant No.2024QNTJ14);the National Key Research and Development Program of China(Grant No.2020YFA0406300)。
The dynamic mechanism of short range interactions between u/d quarks remains an open and challenging problem.In order to reveal this quark dynamics,we perform a systematic analysis of N N,D_(03),and D_(30)systems in t...
关键词:short range interactions DIBARYONS constituent quark models 
Spastin and alsin protein interactome analyses begin to reveal key canonical pathways and suggest novel druggable targets
《Neural Regeneration Research》2025年第3期725-739,共15页Benjamin R.Helmold Angela Ahrens Zachary Fitzgerald P.Hande Ozdinler 
funded by NIH-NIA R01AG061708 (to PHO);Patrick Grange Memorial Foundation (to PHO);A Long Swim (to PHO);CureSPG4 Foundation (to PHO)。
Developing effective and long-term treatment strategies for rare and complex neurodegenerative diseases is challenging. One of the major roadblocks is the extensive heterogeneity among patients. This hinders understan...
关键词:ALS2 alsin amyotrophic lateral sclerosis hereditary spastic paraplegia neurodegenerative diseases personalized medicine precision medicine protein interactome protein-protein interactions SPAST SPASTIN 
A genome-wide association study and transcriptome analysis reveal the genetic basis for the Southern corn rust resistance in maize
《Journal of Integrative Agriculture》2025年第2期453-466,共14页Yang Wang Chunhua Mu Xiangdong Li Canxing Duan Jianjun Wang Xin Lu Wangshu Li Zhennan Xu Shufeng Sun Ao Zhang Zhiqiang Zhou Shenghui Wen Zhuanfang Hao Jienan Han Jianzhou Qu Wanli Du Fenghai Li Jianfeng Weng 
supported by the National Key R&D Program of China(2022YFD1201802);the Shandong Key R&D Program,China(2022CXGC010607);the Science and Technology Innovation Project of Chinese Academy of Agricultural Sciences(CAAS-ZDRW202109);the Agricultural Science and Technology Innovation Project of Chinese Academy of Agricultural Sciences(CAAS-ASTIP2017-ICS);the Subproject of the Major Project of Science and Technology in Shanxi Province,China(202201140601025-1-02)。
Southern corn rust(SCR)is an airborne fungal disease caused by Puccinia polysora Underw.(P.polysora)that adversely impacts maize quality and yields worldwide.Screening for new elite SCR-resistant maize loci or genes h...
关键词:MAIZE southern corn rust genome-wide association study TRANSCRIPTOME 
Integrated metabolomics and proteomics analyses reveal the molecular mechanism underlying the yellow leaf phenotype of Camellia sinensis
《Horticultural Plant Journal》2025年第1期417-430,共14页Nana Li Weizhong He Yufan Ye Mingming He Taimei Di Xinyuan Hao Changqing Ding Yajun Yang Lu Wang Xinchao Wang 
supported by the Project for Collaborative Promotion of Agricultural Major Technology of Zhejiang Province(Grant No.2022XTTGCY01-02);the National Natural Science Foundation of China(Grant Nos.31700615,32172633);the China Agriculture Research System of MOF and MARA(Grant No.CARS19-01A);the Special Project of Zhejiang Province(Grant No.2020R52036)。
The tea plant cultivar‘Zhonghuang 2'(ZH2)possesses albino-induced yellow leaves that contain low levels of catechins but high contents of amino acids.However,the molecular mechanism underlying the yellow leaf phenoty...
关键词:Tea plant Chlorophyll-deficient mutant Chlorophyll biosynthesis Photosynthetic protein Antioxidant capacity Photooxidative stress 
Molecular dynamics simulation:The key to reveal the enrichment mechanisms of helium
《Science China Earth Sciences》2025年第2期643-645,共3页Wenhui LIU 
In recent years,helium and its enrichment mechanisms have been the frontier and attractive research in the field of geological resources(Liu et al.,2024).In the earliest geosciences,noble gases and their isotopes,incl...
关键词:ATTRACTIVE FRONTIER gases 
Ecological Models Reveal a Weakened Population Structure, and Distribution Drivers of Osyris lanceolata (Santalaceae) in the Karamoja Sub-Region, Uganda
《Open Journal of Ecology》2025年第2期153-173,共21页Ben Belden Mugula Samuel Kuria Kiboi James Ireri Kanya Harald Meimberg Manuel Curto Paul Okullo Anthony Egeru Jenipher Biira Salamula Stephen F. Omondi 
Osyris lanceolata is heavily and illegally exploited in East Africa for its essential oils, yet little is known about its population status and ecological requirements. This study examined its population structure and...
关键词:Plant Ecology Hemiparasites Edaphic Drivers Ecological Modelling Multivariate Analysis Essential Oils “R” 
Transcriptomic and behavioral studies reveal that glutamate receptors are involved in depressive-like behavior in adult olive flounder Paralichthys olivaceus
《Aquaculture and Fisheries》2025年第1期115-123,共9页Liangfang Liu Tangsong Feng Mengmeng Shi Huafeng Zou Weiqun Lu 
supported by grants from the National Natural Science Foundation of China(32273103).
Olive flounder(Paralichthys olivaceus),a marine demersal flatfish species,exhibits obvious timid and depressive-like characteristics.Adult olive flounder bury themselves in the sand and present motionless behavior.How...
关键词:Olive flounder Spinal cord RIBOSOME depressive-like behavior Glutamate receptor 
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