PYRROLIDINES

作品数：9被引量：13H指数：2
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相关领域：理学更多>>
相关作者：王春江陈洁曹小平周岭叶新山更多>>
相关机构：北京大学武汉大学兰州大学更多>>
相关期刊：《Green Synthesis and Catalysis》《Chinese Journal of Chemistry》《Journal of Traditional Chinese Medicine》《Science China Chemistry》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Skeletal contraction:A novel strategy to access multisubstituted cyclobutane
《Green Synthesis and Catalysis》2022年第1期1-3,共3页Chunfa Xu V.U.Bhaskara Rao Fen-Er Chen 
C.Xu is grateful to Fuzhou University for the funding support(No.GXRC21051).
The polysubstituted and spirocyclic cyclobutanes were efficiently constructed by the utilization of a novel skeletal contraction strategy which only took one-step synthesis from the readily accessible pyrrolidines.The...
关键词：CYCLOBUTANE Skeletal contraction Hypervalent iodine PYRROLIDINES Piperarboreine B 
Therapeutic effects of salidroside vs pyrrolidine dithiocarbamate against severe acute pancreatitis in rats被引量：4
《Journal of Traditional Chinese Medicine》2022年第1期49-57,共9页QIAN Jing WANG Xiaohong WEI Benzhong ZHOU Guoxiong ZHU Shunxing LIU Chun 
Supported by the Traditional Chinese Medicine Technology Development Plan Project of Jiangsu Province in 2020:Basic and Clinical Study on Salidroside in the Adjuvant Treatment of Severe Acute Pancreatitis(No.YB2020088);the Health Innovation Project of Lvyang Jinfeng Plan of Yangzhou City in 2020:Basic and Clinical Study on Salidroside in the Adjuvant Treatment of Severe Acute Pancreatitis(No.LJ202037)。
OBJECTIVE:To evaluate the therapeutic effectiveness of salidroside(Sal)and pyrrolidine dithiocarbamate(PDTC)against severe acute pancreatitis(SAP)in a rat model.METHODS:Rat models of SAP were established by retrograde...
关键词：rhodioloside PYRROLIDINES ethylenebis(dithiocarbamates) PANCREATITIS AUTOPHAGY NF-kappa B signal transduction 
Stereoselective Synthesis of cis-2,5-Disubstituted Pyrrolidines via Copper-Catalyzed Cyclization of Alkenes
《Chinese Journal of Chemistry》2016年第11期1076-1080,共5页Sai-Hu Cai Bing-Chao Da Jia-Hui Zhou Yun-He Xu Teck-Peng Loh 
We gratefully acknowledge the funding support of the State Key Program of National Natural Science Foundation of China （No. 21432009） and the National Natural Science Foundation of China （No. 21372210）. The authors are grateful to Miss Jun Kee Cheng for her careful proofreading of the final manuscript.
An efficient methodology for the stereoselective synthesis of cis-2,5-disubstituted pyrrolidines using copper catalyst was developed. The corresponding cis-2,5-disubstituted pyrrolidines could be obtained in reasonabl...
关键词：STEREOSELECTIVITY PYRROLIDINES COPPER-CATALYZED CYCLIZATION 
A Facile Access to Fluorinated Pyrrolidines via Catalytic Asymmetric 1,3-Dipolar Cycloaddition of Azomethine Ylides with Methyl a-Fluoroacrylate被引量：2
《Chinese Journal of Chemistry》2012年第11期2714-2720,共7页严定策 李清华 王春江 
Asymmetric 1,3-dipolar cycloaddition of methyl a-fluoroacrylate with azomethine ylides for the construction of optically active fluorinated pyrrolidines bearing one unique fluorinated quaternary and two tertiary stere...
关键词：asymmetric catalysis 1 3-dipolar cycloaddition azomethine ylide methyl a-fluoroacrylate PYRROLIDINE 
Synthesis of bromoallenyl pyrrolidines via 1,4-addition to 1,3-enynes被引量：2
《Science China Chemistry》2011年第1期56-60,共5页WERNESS Jenny B. TANG WeiPing 
the University of Wisconsin-Madison and the American Chemical Society Petroleum Research Fund (48092-G) for funding
The discovery of the novel reactivity of conjugated enynes,mediated by readily available halogenation reagents,opens a broad range of mechanistically unique pathways for the synthesis of highly functionalized chiral a...
关键词：HALOCYCLIZATION HALOGENATION conjugated enynes ALLENE bromoallene PYRROLIDINE 
First Total Synthesis of Hyacinthacine A_6 from the Protected Derivative of Polyhydroxylated Pyrrolidine
《Chemical Research in Chinese Universities》2008年第4期469-472,共4页ZHANG Tao-xiang ZHOU Ling CAO Xiao-ping 
the National Basic Research Program(973 Program)of China(No.2007CB108903);the National Natural Science Foundation of China(No.20621091)
（1S、2R、3R、5R、7aR）-1,2-Dihydroxy-3-hydroxy methyl-5-methylpyrrolizidine（hyacinthacine A6, I） was synthesized by Wittig＇s methodology via the reaction of aldehyde 6, prepared from the partially protected deriva...
关键词：Hyacinthacine A6 PYRROLIDINES Wittig reaction CYCLIZATION 
Mechanisms mediating cholinergic antral circular smooth muscle contraction in rats被引量：4
《World Journal of Gastroenterology》2004年第22期3292-3298,共7页HelenaFWrzos TarunTandon AnnOuyang 
Supported by NIH-grant ROI-DK-34148
AIM:To investigate the pathway(s)mediating rat antral circular smooth muscle contractile responses to the cholinomimetic agent,bethanechol and the subtypes of muscarinic receptors mediating the cholinergic contraction...
关键词：Anesthetics  Local Animals BENZOFURANS BETHANECHOL Calcium Calcium Channel Blockers Cholinergic Agonists Dose-Response Relationship  Drug GTP-Binding Proteins In Vitro Male Muscarinic Antagonists Muscle Contraction Muscle  Smooth Nifedipine Pertussis Toxin Pirenzepine Pyloric Antrum PYRROLIDINES RATS Rats  Sprague-Dawley Receptor  Muscarinic M1 inhibitors Receptor  Muscarinic M2 Receptor  Muscarinic M3 Signal Transduction Tetrodotoxin 
N-Alkoxyl Templates for Diastereoselective Pyrrolidine Synthesis
《Chinese Chemical Letters》2004年第1期1-4,共4页SongQingWANG OmarA.IBRAHIMI PanLI KangZHAO 
Intramolecular cyclization of N-alkoxyl amines are studied for the stereoselective preparation of 2, 4-disubstituted pyrrolidine derivatives. Reduction of oximes under acidic conditions by NaBH3CN afforded the corres...
关键词：SN' reaction PYRROLIDINES OXIME hydroxylamine. 
SYNTHESIS　OF　FULLERENE　PYRROLIDINES　CONTAINING　SUBSTITUTED　PHENYL　GROUPS　THROUGH　AZOMETHINE　YLIDE　ADDITION被引量：1
《Chinese Chemical Letters》1995年第12期1033-1036,共4页Zhou, DJ Gan, LB Tan, HS Luo, CP Huang, CH Pan, JQ Lu, MJ Wu, Y 
Terephthalaldehyde reacts with sarcosine to form azomethine ylide, which adds to C60 according to a[3+2] cycloaddition process to form fullerene pyrrolidine. The same addition reaction can also be applied to other sub...
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