GLYCOSYLPHOSPHATIDYLINOSITOL

作品数：8被引量：11H指数：2
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相关领域：医药卫生更多>>
相关作者：周玉萍田长恩段琼唐建华谭超超更多>>
相关机构：广州大学中南大学更多>>
相关期刊：《Acta Biochimica et Biophysica Sinica》《Cellular & Molecular Immunology》《微生物学通报》《天然产物研究与开发》更多>>
相关基金：国家自然科学基金中国博士后科学基金高等学校学科创新引智计划更多>>
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Inherited glycosylphosphatidylinositol deficiency:a review from molecular and clinical perspectives被引量：1
《Acta Biochimica et Biophysica Sinica》2024年第8期1234-1243,共10页Shan Li Qi Tang Yuwu Jiang Xing Chen 
supported by the grants from the National Natural Science Foundation of China(Nos.22321005 and 22037001 to X.C.;Nos.22A20339,81601131,82071263,and 12026606 to Y.J.);the Beijing Natural Science Foundation(No.5244034 to Q.T.);supported by the National Postdoctoral Program for Innovative Talent.X.C.is a recipient of Xplorer Prize.
Glycosylphosphatidylinositol(GPI)is a highly conserved post-translational modification in eukaryotes,which is essential for anchoring various proteins to the cell surface.Dysfunction of GPI biogenesis leads to human d...
关键词：GLYCOSYLATION GLYCOSYLPHOSPHATIDYLINOSITOL inherited GPl deficiency 
丝状真菌表面展示技术研究进展被引量：2
《微生物学通报》2023年第12期5574-5587,共14页曾祥伟 邹瑶 周玉萍 田长恩 
广东省自然科学基金(2020A1515011423)。
丝状真菌表面展示技术是将表达的目的蛋白固定在丝状真菌细胞表面的一项新兴基因工程技术。丝状真菌具有极强的蛋白质分泌能力和良好的蛋白质翻译后加工能力,因而越来越多的丝状真菌表面展示技术得到开发和应用。本文就丝状真菌表面展...
关键词：丝状真菌 表面展示技术 糖基磷脂酰肌醇(glycosylphosphatidylinositol GPI)锚定蛋白 细胞壁 
Development of surface displaying system for heterologous protein expression in Candida tropicalis
《Systems Microbiology and Biomanufacturing》2023年第2期298-311,共14页Tingting Wang Haibing Zhang Mengxuan Li Jiaxi Zheng Yuanyuan Xia Haiquan Yang Wei Shen Xianzhong Chen 
supported by the 111 Project(No.111-2-06);National Natural Science Foundation of China(32001064);Key Research and Development Program of China(2021YFC2100102-03);China Postdoctoral Science Foundation(2020M671331);Postgraduate Research and Practice Innovation Program of Jiangsu Province(No.KYCX20-1807).
The purpose of this study was to assess the potential application of cell surface display in Candida tropicalis.Surface display gene cassettes were constructed using five anchoring proteins from Saccharomyces cerevisi...
关键词：Yeast surface display Anchoring protein Glycosylphosphatidylinositol(GPI) Α-AMYLASE Β-GLUCOSIDASE Whole cell catalysis 
Generation of HIY-resistant cells with a single-domain antibody:implications for HIV-1 gene therapy被引量：3
《Cellular & Molecular Immunology》2021年第3期660-674,共15页Hongliang Jin Xiaoran Tang Li Li Yue Chen Yuanmei Zhu Huihui Chong and Yuxian He 
supported by grants from the CAMS Innovation Fund for Medical Sciences(2017-I2M-1-014);National Science and Technology Major Project of China(2018ZX10301103 and 2017ZX10202102-001-003);National Natural Science Foundation of China(81630061).
The cure or functional cure of the"Berlin patient"and"London patient"indicates that infusion of HIV-resistant cells could be a viable treatment strategy.Very recently,we genetically linked a short-peptide fusion inhib...
关键词：HIV-1 gene therapy resistant cell single-domain antibody GLYCOSYLPHOSPHATIDYLINOSITOL 
Plant glycosylphosphatidylinositol anchored proteins at the plasma membrane-cell wall nexus被引量：3
《Journal of Integrative Plant Biology》2018年第8期649-669,共21页Trevor H.Yeats Antony Bacic Kim L.Johnson 
supported by the ARC Centre of Excellence in Plant Cell Walls grant (CE1101007);supported by a postdoctoral fellowship from the Philomathia Foundation
Approximately 1% of plant proteins are predicted to be post-translationally modified with a glycosylphospha- tidylinositol （GPI） anchor that tethers the polypeptide to the outer leaflet of the plasma membrane. Where...
关键词：GPI Plant glycosylphosphatidylinositol anchored proteins at the plasma membrane-cell wall nexus 
Release of exosomes and microvesicles harbouring specific RNAs and glycosylphosphatidylinositol-anchored proteins from rat and human adipocytes is controlled by histone methylation
《American Journal of Molecular Biology》2012年第3期187-209,共23页Günter Müller Marion Schneider Johann Gassenhuber Susanne Wied 
The transfer of proteins and nucleic acids from donor to acceptor cells via small membrane vesicles has been implicated with (patho)physiological consequences. Previously the upregulation of esterification and downreg...
关键词：cAMP EPIGENETIC Control EXOSOMES GLIMEPIRIDE GLYCOSYLPHOSPHATIDYLINOSITOL Lipid Metabolism Microparticles miRNA MICROVESICLES 
Take-over:multiple mechanisms of inter-adipocyte communication
《Journal of Molecular Cell Biology》2011年第2期81-90,共10页Gunter Muller 
Adipose tissue mass in mammals is thought to expand with an increase in both volume and total number of the adipocytes.Recent findings suggest that in normal-weight as well as obese individuals,the adipocyte number is...
关键词：ADIPOKINES fat cells GLYCOSYLPHOSPHATIDYLINOSITOL lipid droplets lipid metabolism MICROVESICLES OBESITY type 2 diabetes 
Synthesis of a malaria candidate glycosylphosphatidylinositol （GPI） structure： A strategy for fully inositol acylated and phosphorylated GPIs被引量：2
《天然产物研究与开发》2004年第4期306-306,共1页LuJ JayaprakashKN SchlueterU Fraser-ReidB 
A congener of the glycosylpbosphatidylinositol (GPI) membrane anchor present on the cell surface of the malaria pathogen Plasmodium, falciparum has been synthesized. This GPI is an example of a small number of such me...
关键词：糖基磷脂酰环己六醇 疟疾 环己六醇 磷酸化 酰化 生物合成 寄生物 
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