MICROVESICLES

作品数：48被引量：237H指数：9
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相关领域：医药卫生生物学更多>>
相关作者：王华张亚琴邢臣径周妙妮熊晶更多>>
相关机构：武汉大学山东大学华中科技大学安徽医科大学更多>>
相关期刊：《Cellular & Molecular Immunology》《Mechanobiology in Medicine》《Acta Pharmacologica Sinica》《Science China Chemistry》更多>>
相关基金：国家自然科学基金天津市自然科学基金国家教育部博士点基金国家重点基础研究发展计划更多>>
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Melanoma-derived extracellular vesicles transfer proangiogenic factors
《Oncology Research》2025年第2期245-262,共18页MAGDALENA WILCZAK MAGDALENA SURMAN MAŁGORZATA PRZYBYŁO 
supported by grants from the Jagiellonian University,Poland(N18/DBS/000007);the Polish National Science Centre(2018/31/N/NZ4/03787).
Angiogenesis,the expansion of pre-existing vascular networks,is crucial for normal organ growth and tissue repair,but is also involved in various pathologies,including inflammation,ischemia,diabetes,and cancer.In soli...
关键词：Angiogenesis EXOSOMES Extracellular Vesicles(EVs) MELANOMA MICROVESICLES 
Microvesicles derived from mesenchymal stem cells: A promising therapeutic strategy for acute respiratory distress syndrome-related pulmonary fibrosis?
《World Journal of Stem Cells》2025年第1期66-70,共5页Zhao Zhang Xin-Yun Shan Ce Liang Lan Zhao Xiao-Qian Shan 
Pulmonary fibrosis significantly contributes to the pathogenesis of acute respiratory distress syndrome(ARDS),markedly increasing patient mortality.Despite the established anti-fibrotic effects of mesenchymal stem cel...
关键词：Microvesicles derived from mesenchymal stem cells Acute respiratory distress syndrome Pulmonary fibrosis Hepatocyte growth factor Mesenchymal stromal cells 
Microvesicles derived from mesenchymal stem cells inhibit acute respiratory distress syndrome-related pulmonary fibrosis in mouse partly through hepatocyte growth factor被引量：1
《World Journal of Stem Cells》2024年第8期811-823,共13页Qi-Hong Chen Ying Zhang Xue Gu Peng-Lei Yang Jun Yuan Li-Na Yu Jian-Mei Chen 
Research Project of Jiangsu Provincial Health Commission,No.Z2022008;and Research Project of Yangzhou Health Commission,No.2023-2-27.
BACKGROUND Pulmonary fibrosis is one of the main reasons for the high mortality rate among acute respiratory distress syndrome(ARDS)patients.Mesenchymal stromal cell-derived microvesicles(MSC-MVs)have been shown to ex...
关键词：Microvesicles derived from mesenchymal stem cells Acute respiratory distress syndrome Pulmonary fibrosis Hepatocyte growth factor Mesenchymal stromal cells 
Pericytes protect rats and mice from sepsis-induced injuries by maintaining vascular reactivity and barrier function:implication of miRNAs and microvesicles被引量：3
《Military Medical Research》2024年第1期1-18,共18页Zi-Sen Zhang Yi-Yan Liu Shuang-Shuang He Dai-Qin Bao Hong-Chen Wang Jie Zhang Xiao-Yong Peng Jia-Tao Zang Yu Zhu Yue Wu Qing-Hui Li Tao Li Liang-Ming Liu 
supported by the Key Projects and Innovation Group of National Natural Science Foundation of China(81830065),the Innovation Groups of NSFC(81721001),and the Young Scientists Fund(82102279).
Background Vascular hyporeactivity and leakage are key pathophysiologic features that produce multi-organ damage upon sepsis.We hypothesized that pericytes,a group of pluripotent cells that maintain vascular integrity...
关键词：PERICYTE Vascular reactivity Vascular permeability CX43 MICROVESICLE 
Mesenchymal stem cell secretome and extracellular vesicles for neurodegenerative diseases: Risk-benefit profile and next steps for the market access被引量：3
《Bioactive Materials》2023年第11期16-35,共20页Lorella Giovannelli Elia Bari Claudio Jommi Fulvio Tartara Daniele Armocida Diego Garbossa Fabio Cofano Maria Luisa Torre Lorena Segale 
Interreg V-A Italy-Switzerland 2014-2020;ATEx-Advanced Therapies Experiences.Project ID 3859153;by the Italian Ministry of Health(Project MINSAL_INVITRO_TUMOR,CUP E85F21003590001).
Neurodegenerative diseases represent a growing burden on healthcare systems worldwide. Mesenchymal stem cells (MSCs) have shown promise as a potential therapy due to their neuroregenerative, neuroprotective, and immun...
关键词：EXOSOMES Microvesicles Secretome Mesenchymal stem cells Secretome formulation Brain regeneration 
Glutamine metabolic microenvironment drives M2 macrophage polarization tomediate trastuzumab resistance in HER2-positive gastric cancer被引量：6
《Cancer Communications》2023年第8期909-937,共29页Xingbin Hu Zhenfeng Ma Beibei Xu Shulong Li Zhiqi Yao Bishan Liang Jiao Wang Wangjun Liao Li Lin Chunling Wang Siting Zheng Qijing Wu Qiong Huang Le Yu Fenghua Wang Min Shi 
National Natural Science Foundation of China,Grant/Award Number:82073325。
Background:Trastuzumab is a first-line targeted therapy for human epidermal growth factor receptor-2(HER2)-positive gastric cancer.However,the inevitable occurrence of acquired trastuzumab resistance limits the drug b...
关键词：Gastric cancer glutamine metabolism MACROPHAGE mathematical model MICROVESICLES TRASTUZUMAB 
Circulating endothelial microvesicles and their carried miR-125a 5p:potential biomarkers for ischaemic stroke被引量：2
《Stroke & Vascular Neurology》2023年第2期89-102,共14页Xiaotang Ma Xiaorong Liao Jiehong Liu Yan Wang Xiang Wang Yanfang Chen Xiaojian Yin Qunwen Pan 
supported by National Natural Science Foundation of China(NSFC,81770500,81870580);Guangdong Basic and Applied Basic Research Foundation(2019A1515011574,2020A1515010089,2021A1515010982).
Background Endothelial microvesicles(EMVs)are closely associated with the status of endothelial cells(ECs).Our earlier study has shown that EMVs could exert protective roles in ECs by transferring their carried miR-12...
关键词：MIR ELEVATED protective 
Platelet-derived microvesicles drive vascular smooth muscle cell migration via forming podosomes and promoting matrix metalloproteinase-9 activity被引量：1
《Mechanobiology in Medicine》2023年第1期44-50,共7页He Ren Jiahe Chen Kai Huang Ying-Xin Qi 
supported by grants from the National Natural Science Foundation of China[grant numbers 12032003 and 12102261].
We have shown that platelet-derived microvesicles(PMVs)induce abnormal proliferation,migration,and energy metabolism of vascular smooth muscle cells(VSMCs)after vascular intimal injury.Here,we examined a novel role of...
关键词：Platelet-derived microvesicles(PMVs) Vascular smooth muscle cells(VSMCs) PODOSOME Matrix metalloproteinase-9(MMP-9) Migration 
Microvesicles with mitochondrial content are increased in patients with sepsis and associated with inflammatory responses被引量：2
《World Journal of Clinical Cases》2023年第2期342-356,共15页Hai-Jun Zhang Jin-Yi Li Chao Wang Guo-Qiang Zhong 
BACKGROUND Endothelial activation plays an important role in sepsis-mediated inflammation,but the triggering factors have not been fully elucidated.Microvesicles carrying mitochondrial content(mitoMVs)have been implic...
关键词：SEPSIS MICROVESICLES MITOCHONDRIA Microvesicles carrying mitochondrial content 
Microvesicles:the functional mediators in sorafenib resistance
《Cancer Drug Resistance》2022年第3期749-761,共13页Cong He Doulathunnisa Jaffar Ali Bo Sun Bei-Cheng Sun Zhong-Dang Xiao 
supported by the National Natural Science Foundation of China(No.81671807);the Key Research&Development Program of Jiangsu Province(BE2020777);Fundamental Research Funds for the Central Universities(2242018K3DN05)to Z.D.X.;Fundamental Research Funds for the Central Universities(2242021K10004)to B.S.;the Jiangsu Postdoctoral Research Foundation(1601001C);Fundamental Research Funds for the Central Universities(2242016R20017)to J.A.D.
Overcoming drug resistance in cancer therapies remains challenging,and the tumor microenvironment plays an important part in it.Microvesicles(MVs)are functional natural carriers of cellular information,participate in ...
关键词：Microvesicles(MVs) sorafenib resistance tumor microenvironment cancer therapy 
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