supported by research funding from the National Natural Science Foundation of China(82141130,82372735);the Sichuan Province Science and Technology Support Program(2019YJ0724,2023NSFSC1519);the China Postdoctoral Science Foundation(2022M712240);West China School/Hospital of Stomatology,Sichuan University(RCDWJS2022-10).
Head and neck squamous cell carcinoma(HNSCC)is the sixth most common malignant tumor worldwide.Considering its special anatomical site and the progressive resistance to chemotherapy drugs,the development of more effec...
supported by the National Natural Science Foundation of China(32171359,31971292,32025021 and 32111540257);the General Research Program of Zhejiang Provincial Department of Health(WKJ-ZJ-2137);the Zhejiang Province Financial Supporting(2020C03110 and 2023C04017);the Key Scientific and Technological Special Project of Ningbo City(2020Z094);the Natural Science Foundation of Ningbo(202003N4001,2021J240 and 20221JCGY010661).
Since apoptosis of foam,cells can induce plaque instability,reducing intracellular lipid content while protecting foam cells from apoptosis is beneficial for the safe and efficient therapy of atherosclerosis.In this s...
support from Wenzhou Institute,University of Chinese Academy of Sciences(WIUCASQD2019002,WIUCASZZXF21005);the First Affiliated Hospital of Wenzhou Medical University.
Large size bone defects affect human health and remain a worldwide health problem that needs to be solved immediately.3D printing technology has attracted substantial attention for preparing penetrable multifunctional...
supported by the National Natural Science Foundation of China(U20A20254,U1732127 and 51772074);Natural Science Foundation of Hebei Province(C2020201025);Central Government Guided Local Science and Technology Development Project of Hebei Province(226Z1302G);Natural Science Interdisciplinary Research Program of Hebei University(DXK202002);Research Innovation Team of College of Chemistry and Environmental Science of Hebei University(hxkytd-py2103).
The non-specific leakage of drugs from nanocarriers seriously weakened the safety and efficacy of chemotherapy,and it was very critical of constructing tumor microenvironment(TME)-responsive delivery nanocarriers,achi...
financially supported by the National Natural Science Foundation of China(grants No.52130302,21961160721).
Since the pioneering work of Messersmith’s group discovering that polydopamine(PDA)can serve to adhere to many types of materials,the PDA coating has,as a biomimetic approach,been widely used to enhance cell adhesion...
support from National Natural Science Foundation of China(NSFC81602736);China Postdoctoral Science Foundation(2018M632684);Shandong Provincial Natural Science Foundation(ZR2019PH084);Liaocheng People’s Hospital Youth Research Fund(LYQN201935).
Photothermal therapy(PTT)has emerged as a promising cancer therapeutic method.In this study,Arg-Gly-Asp(RGD)peptide-conjugated polydopamine-coated gold nanostars(Au@PDA-RGD NPs)were prepared for targeting PTT of hepat...
This study was supported by the National Key Research and Development Project(2017YFB0702600,2016YFB0700800);China Postdoctoral Science Foundation(2019M662830);National Natural Science Foundation of China(51901239);Natural Science Foundation of Guangdong Province,China(Grant No.2020A1515011447);The Joint Fund of Ministry of Education for Equipment Pre-research(No.6141A02022632);Scientific and Technological Projects of Guangzhou,China(Grant No.202002030283).
Infection and insufficient osteointegration are the main causes of orthopedic implant failure.Furthermore,activating favorable inflammation response is vital to the fast osteointegration of implants.Therefore,endowing...
supported by the National Key Research and Development Program of China(2017YFB0702504);the National Natural Science Foundation of China(NSFC Project 81801853);the Postdoctoral Science Foundation of China(2018M633400);the Sichuan Science and Technology Program(19GJHZ0058).
NO is the earliest discovered gas signal molecule which is produced by normal healthy endothelial cells,and it has many functions,such as maintaining cardiovascular homeostasis,regulating vasodilation,inhibiting intim...
This work is supported by the NSFC(Project 51173149);the Ministry of Science and Technology Project of China(Key Basic Research Project No.2011CB606204).
In this study,the polydopamine(PDA)film was coated on polished 316Lss and then thermally treated at 150C(labeled as PDA-Th150),and the stability of coatings was also investigated.Straining test indicated that PDA-Th1...