Background:Beverages play a positive role in a balanced diet.Beverages can provide an enjoyable and refreshing mind to reach a particular target.In beverages,date-rape drugs,such as Rohypnol,gamma-hydroxybutyric acid,...
Written informed consent was obtained from the children’s guardians to publish their cases,and the Research Ethics Committee of Children’s Hospital of Jiangxi Province provided approval for this study(approval number is JXSETYY-YXKY-20210035).
Background SYNGAP1 is a signifcant genetic risk factor for global developmental delay,autism spectrum disorder,and epileptic encephalopathy.De novo loss-of-function variants in this gene cause a neurodevelopmental dis...
Background: Hydrolysis improves the sensitivity of drug detection for drug classes such as opiates/opioids and benzodiazepines, which are highly metabolized by glucuronidation and sulfation and should...
The study was financially supported by the Project of the National Natural Sciences Foundation of China(81373239);The Innovation and Business Starting-oriented training program of College Students in Sichuan Province(C2020113713).
Drug-facilitated sexual assault(DFSA)is a sexual act in which the victim is unable to give or rescind consent due to alcohol or drug intoxication,which involved the abuse of benzodiazepines around the world.Convention...
To the Editor: With interest, we read the article by Su et al[1] about the antiepileptic drug (AED) treatment of 17 patients with genetically confirmed myoclonic epilepsy with ragged-red fibers (MERRF) syndrome. It wa...
This study wassupported partly by grants from the National Natural Science Foundation of China (No. 81873786), Programs for Science and Technology Development of Jinan (No. 201704102), Lateral Chimerism Project of Shandong University (No. 12671731), and the Programs for Science and Technology Development of Binzhou (No. 2014ZC0136).
Background: Treatment of myoclonic seizures in myoclonic epilepsy with ragged-red fibers (MERRFs) has been empirical and ineffective. Guideline on this disease is not available. Additional trials must be conducted ...
Shanghai Municipal Hospital's Emerging Frontier Technology Joint Research Project(SHDC12012109);Shanghai Open Project of Key Laboratory of Severe Psychiatry(13dz2260500)
Background Agitation is very common in patients with acute stage schizophrenia, and injection of antipsychotics and clonazepam is widely used. Network meta-analysis of these comparisons among three injection treatment...
Background: The clinical characteristics of burning mouth syndrome (BMS) are not fully understood. We investigated the profiles of BMS patients, characteristics associated with BMS, and the available treatment methods...
Quantum chemical calculations have been carried out to investigate the vibrational frequencies of clonazepam. The FTIR spectrum of clonazepam was recorded in the region 4000 to 400 cm–1 in the solid phase. The optimi...
The sedative compounds in two traditional Chinese medicines were studied. These compounds are present in the medicinal herbs “Zao Ren” and “Lu Lu Tong”. The samples were first extracted by ethanol and pre-treated ...