HYPERCHOLESTEREMIA

作品数:3被引量:2H指数:1
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相关领域:医药卫生更多>>
相关期刊:《Acta Pharmacologica Sinica》《Journal of Hainan Medical University》《Acta Pharmaceutica Sinica B》更多>>
相关基金:国家自然科学基金更多>>
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Urolithin A promotes atherosclerotic plaque stability by limiting inflammation and hypercholesteremia in Apolipoprotein E–deficient mice
《Acta Pharmacologica Sinica》2024年第11期2277-2289,共13页Meng-yun Xu Jing-jing Xu Li-jing Kang Zheng-hong Liu Mei-ming Su Wen-qi Zhao Zhi-hua Wang Lu Sun Jian-bo Xiao Paul C.Evans Xiao-yu Tian Li Wang Yu Huang Xin-miao Liang Jian-ping Weng Suo-wen Xu 
supported by grants from the National Key R&D Program of China(Grant No.2021YFC2500500);the National Natural Science Foundation of China(Grant No.82370444,82070464,82003741);the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB38010100);supported by the Program for Innovative Research Team of The First Affiliated Hospital of USTC(CXGG02);Anhui Provincial Key Research and Development Program(Grant No.202104j07020051);Anhui Provincial Natural Science Foundation(Grant No.2208085J08).
Urolithin A(UroA),a dietary phytochemical,is produced by gut bacteria from fruits rich in natural polyphenols ellagitannins(ETs).The efficiency of ETs metabolism to UroA in humans depends on gut microbiota.UroA has sh...
关键词:atherosclerosis urolithin A INFLAMMATION YAP/TAZ endothelial cells 
The role of CYP1A1/2 in cholesterol ester accumulation provides a new perspective for the treatment of hypercholesterolemia被引量:2
《Acta Pharmaceutica Sinica B》2023年第2期648-661,共14页Jian Lu Xuyang Shang Bingyi Yao Dongyi Sun Jie Liu Yuanjin Zhang He Wang Jingru Shi Huaqing Chen Tieliu Shi Mingyao Liu Xin Wang 
supported in whole or part by grants from the National Natural Science Foundation of China(81773808,82274010);the Science and Technology Commission of Shanghai Municipality(18430760400,China);the Jointed PI Program from Shanghai Changning Maternity and Infant Health Hospital(2019CNECNUPI02,China);the Fundamental Research Funds for the Central Universities(China);ECNU Construction Fund of Innovation and Entrepreneurship Laboratory(China);supported from ECNU Multifunctional Platform for Innovation(011,China);the Instruments Sharing Platform of School of Life Sciences,East China Normal University(Shanghai,China)。
Cholesterol is an important precursor of many endogenous molecules.Disruption of cholesterol homeostasis can cause many pathological changes,leading to liver and cardiovascular diseases.CYP1A is widely involved in cho...
关键词:HYPERLIPIDEMIA HYPERCHOLESTEREMIA Cholesterol CYP1A LIPIDOSIS LXR CES1 LANSOPRAZOLE 
Effect of rosuvastatin on the serum lipid and inflammatory cytokines in patients with diabetes and hypercholesteremia
《Journal of Hainan Medical University》2017年第4期79-81,共3页Jie Xia Chuntian Cai 
Objective:To explore the effect of rosuvastatin on the blood glucose, blood lipid, inflammatory cytokines, and liver function in patients with diabetes and hypercholesteremia.Methods: A total of 108 patients with diab...
关键词:ROSUVASTATIN DIABETES and HYPERCHOLESTEREMIA BLOOD glucose BLOOD LIPID Inflammatory CYTOKINE 
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