supported by grants from the National Key R&D Program of China(Grant No.2021YFC2500500);the National Natural Science Foundation of China(Grant No.82370444,82070464,82003741);the Strategic Priority Research Program of the Chinese Academy of Sciences(Grant No.XDB38010100);supported by the Program for Innovative Research Team of The First Affiliated Hospital of USTC(CXGG02);Anhui Provincial Key Research and Development Program(Grant No.202104j07020051);Anhui Provincial Natural Science Foundation(Grant No.2208085J08).
Urolithin A(UroA),a dietary phytochemical,is produced by gut bacteria from fruits rich in natural polyphenols ellagitannins(ETs).The efficiency of ETs metabolism to UroA in humans depends on gut microbiota.UroA has sh...
supported in whole or part by grants from the National Natural Science Foundation of China(81773808,82274010);the Science and Technology Commission of Shanghai Municipality(18430760400,China);the Jointed PI Program from Shanghai Changning Maternity and Infant Health Hospital(2019CNECNUPI02,China);the Fundamental Research Funds for the Central Universities(China);ECNU Construction Fund of Innovation and Entrepreneurship Laboratory(China);supported from ECNU Multifunctional Platform for Innovation(011,China);the Instruments Sharing Platform of School of Life Sciences,East China Normal University(Shanghai,China)。
Cholesterol is an important precursor of many endogenous molecules.Disruption of cholesterol homeostasis can cause many pathological changes,leading to liver and cardiovascular diseases.CYP1A is widely involved in cho...
Objective:To explore the effect of rosuvastatin on the blood glucose, blood lipid, inflammatory cytokines, and liver function in patients with diabetes and hypercholesteremia.Methods: A total of 108 patients with diab...