HAEMOCHROMATOSIS

作品数：7被引量：19H指数：2
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Haemochromatosis revisited被引量：1
《World Journal of Hepatology》2022年第11期1931-1939,共9页Aline Morgan Alvarenga Pierre Brissot Paulo Caleb Junior Lima Santos 
Haemochromatosis is a genetic disease caused by hepcidin deficiency,responsible for an increase in intestinal iron absorption.Haemochromatosis is associated with homozygosity for the HFE p.Cys282Tyr mutation.However,r...
关键词：HAEMOCHROMATOSIS Iron overload HFE Molecular diagnosis HEPCIDIN 
Animal models for hepatocellular carcinoma arising from alcoholic and metabolic liver diseases
《Hepatoma Research》2020年第2期39-54,共16页Ken Liu Jinbiao Chen Geoffrey W.McCaughan 
Hepatocellular carcinoma (HCC) is a major and increasing cause of clinical and economic burden worldwide. Now that there are effective therapies to control or eradicate viral aetiologies, the landscape of HCC is chang...
关键词：Hepatocellular carcinoma animal models mouse models non-alcoholic fatty liver disease ALCOHOL HAEMOCHROMATOSIS 
Transforming growth factor-β and toll-like receptor-4 polymorphisms are not associated with fibrosis in haemochromatosis被引量：1
《World Journal of Gastroenterology》2013年第48期9366-9376,共11页Marnie J Wood Lawrie W Powell Jeannette L Dixon V Nathan Subramaniam Grant A Ramm 
Supported by NHMRC Medical Postgraduate Scholarship and the Royal Brisbane and Women’s Hospital Research Foundation to Wood MJ;the National Health and Medical Research Council(NHMRC)to Ramm GA and Powell LW;the recipient of an NHMRC Senior Research Fellowship,1024672 to Subramaniam VN;an NHMRC Senior Research Fellowship,No.552409 to Ramm GA
AIM:To investigate the role of genetic polymorphisms in the progression of hepatic fibrosis in hereditary haemochromatosis.METHODS:A cohort of 245 well-characterised C282Y homozygous patients with haemochromatosis was...
关键词：HAEMOCHROMATOSIS Genetic polymorphism Liver FIBROSIS TOLL-LIKE receptor 4 Interleukin 10 Monocyte CHEMOATTRACTANT protein 1 Chemokine(C-C motif) ligand 2 Transforming growth factor beta 8-oxoguanine DNA GLYCOSYLASE 
Iron:An emerging factor in colorectal carcinogenesis被引量：4
《World Journal of Gastroenterology》2010年第6期663-672,共10页Anita CG Chua Borut Klopcic Ian C Lawrance John K Olynyk Debbie Trinder 
Supported by Grants from the Cancer Council of Western Australia and Fremantle Hospital Medical Research Foundation
The carcinogenic potential of iron in colorectal cancer(CRC) is not fully understood.Iron is able to undergo reduction and oxidation,making it important in many physiological processes.This inherent redox property of ...
关键词：IRON HAEM Colorectal cancer Oxidative stress Inflammation HAEMOCHROMATOSIS 
Non-HFE haemochromatosis被引量：2
《World Journal of Gastroenterology》2007年第35期4690-4698,共9页Daniel F Wallace V Nathan Subramaniam 
Non-HFE hereditary haemochromatosis （HH） refers to a genetically heterogeneous group of iron overload disorders that are unlinked to mutations in the HFE gene. The four main types of non-HFE HH are caused by mutatio...
关键词：HAEMOCHROMATOSIS Iron overload Non-HFE Juvenile haemochromatosis HEMOJUVELIN Hepcidin Transferrin receptor 2 FERROPORTIN 
Role of iron in hepatic fibrosis: One piece in the puzzle被引量：11
《World Journal of Gastroenterology》2007年第35期4746-4754,共9页Marie A Philippe Richard G Ruddell Grant A Ramm 
NHMRC Program Grant 339400
Iron is an essential element involved in various biological pathways. When present in excess within the cell, iron can be toxic due to its ability to catalyse the formation of damaging radicals, which promote cellular...
关键词：IRON FIBROSIS Oxidative stress Hepatic stellate cell HAEMOCHROMATOSIS Hepatitis C Non-alcoholic fatty liver disease Alcoholic liver disease 
The epidemiology of hyperferritinaemia
《World Journal of Gastroenterology》2006年第36期5866-5869,共4页Sarah Hearnshaw Nick Paul Thompson Andrew McGill 
AIM： To discover the causes of markedly raised ferritin levels in patients seen at a teaching hospital in Newcastle Upon Tyne, United Kingdom. METHODS： Demographic and medical data were collected for all patients ov...
关键词：FERRITIN EPIDEMIOLOGY HAEMOCHROMATOSIS 
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