BUTYLPHTHALIDE

作品数:20被引量:75H指数:3
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相关领域:医药卫生更多>>
相关作者:常雁褚凤鸣乔晋萍郭宗儒赵丽艳更多>>
相关机构:湖南省脑科医院中国医学科学院北京协和医学院中南大学更多>>
相关期刊:《Chinese Medical Journal》《World Journal of Meta-Analysis》《外文科技期刊数据库(文摘版)医药卫生》《Stroke & Vascular Neurology》更多>>
相关基金:国家自然科学基金更多>>
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The Effect of Ginkgo Biloba Leaf Dropping Pill Combined with Butylphthalide Capsule on Cognitive Dysfunction in Patients after Acute Ischemic Stroke and Its Impact on Serum Cytokines
《Journal of Biosciences and Medicines》2024年第7期252-262,共11页Yaojie Cai Yuping He Gang Yang Yan Chen 
Objective: To investigate the therapeutic effect of Ginkgo biloba extract dropping pills combined with butylphthalide capsules on cognitive dysfunction in patients after acute ischemic stroke (AIS) and its impact on s...
关键词:Acute Ischemic Stroke Ginkgo Biloba Leaf Drop Pills Butylphthalein Cognitive Impairment 
Safety of butylphthalide and edaravone in patients with ischemic stroke:a multicenter real-world study被引量:3
《Journal of Geriatric Cardiology》2023年第4期293-308,共16页Shu-Xian LYU Dong-Fang QIAN Yu-Fei FENG Cheng-Wu SHEN Lu-Bo GUO Jian-Tao LYU Peng-Fei JIN Ting LI Si-Yuan TAN Zi-Xuan ZHANG Lin HUANG Xue ZHONG Le-Qun SU Xin HU Xin HUANG Xue-Yan CUI 
supported by the China Society for Drug Regulation(CSDR)Project:exploration of criteria for post-marketing risk assessment of medications using real-world data(DRM2021008);the Special Clinical Pharmacy Program of Shandong Medical Association(YXH2022ZX004)。
BACKGROUND Butylphthalide(NBP)and edaravone(EDV)injection are common acute ischemic stroke medications in China,but there is a lack of large real-world safety studies on them.This study aimed to determine the incidenc...
关键词:PATIENTS DRUGS injection 
Effect of Butylphthalide Sodium Chloride Combined with Argatroban on Neurological Function in Patients with Ischemic Stroke
《外文科技期刊数据库(文摘版)医药卫生》2022年第9期106-109,共4页JIANGMin 
Objective: to explore the feasibility and effectiveness of butylphthalide sodium chloride combined with argatroban in the clinical treatment of patients with ischemic stroke. Methods: the study was conducted in a retr...
关键词:ischemic stroke butylphthalide sodium chloride ARGATROBAN neurological function daily living abi 
Dl-3-n butylphthalide attenuates brain injury caused by cortical infarction accompanied by cranial venous drainage disturbance被引量:4
《Stroke & Vascular Neurology》2022年第3期222-236,共15页Kangping Song Xiuli Zeng Xiaomei Xie Rongxuan Zhu Jianye Liang Guobing Chen Li’an Huang 
This study was funded by the National Natural Science Foundation of China(No.81971120);the Science and Technology Planning Project of Guangdong Province of China(No 2017A02021520081971120).
Background Cerebral venous disorder may have a harmful effect on ischaemic stroke;however,the underlying mechanism remains to be elucidated.Although Dl-3-n butylphthalide is a multitarget agent for antiischaemic strok...
关键词:protective INFARCTION DISTURBANCE 
Evaluation of Xuesaitong Combined with Butylphthalide Injection on the Improvement of Neurological Function in Patients with Acute Ischemic Stroke
《外文科技期刊数据库(文摘版)医药卫生》2022年第5期134-138,共5页FANFuping 
Objective: to study the curative effect of butylphthalide combined with Xueshuantong on ischemic stroke and its influence on neurological function. Methods: 100 patients with ischemic stroke in our hospital were selec...
关键词:ischemic stroke XUESHUANTONG BUTYLPHTHALIDE neurological function 
Clinical Experience of Intravenous Thrombolytic Therapy of Butylphthalide Combined with Urokinase in Acute Cerebral Infarction
《外文科技期刊数据库(文摘版)医药卫生》2022年第2期173-176,共4页LUOZhijun 
Objective: to explore the clinical experience of intravenous thrombolysis of butylphthalide combined with urokinase in the treatment of acute cerebral infarction. Methods: from January 2018 to January 2020 in our hosp...
关键词:BUTYLPHTHALIDE intravenous thrombolysis with urinary hormone enzyme acute cerebral infarction NIHSS vascular recanalization rateIntroduction 
Vascular protection and regenerative effects of intranasal DL-3-N butylphthalide treatment after ischaemic stroke in mice被引量:5
《Stroke & Vascular Neurology》2021年第1期74-79,共6页Mengyao Qu Jingjie Zhao Yingying Zhao Jinmei Sun Liping Liu Ling Wei Yongbo Zhang 
the National Natural Science Foundation of China(81371355 to YZ,81500989 to YZ,81671191 to YZ and 81820108012 to LL).
Objective To investigate the effects of DL-3-N butylphthalide(NBP)via intranasal delivery after ischaemic stroke in mice.Methods C57BL/6 mice were divided into three groups:sham,stroke with vehicle and stroke with NBP...
关键词:NASAL protective TREATMENT 
Tongqiao Huoxue Decoction combined with butylphthalide in the treatment of acute ischemic stroke and its effect on VEGF被引量:2
《Journal of Hainan Medical University》2021年第2期21-26,共6页Xin Chen Ying-Qiong Xiong Shao-Min Cheng 
Science and Technology Plan of Health and Family Planning Commission of Jiangxi Province(No.20195025);State Administration of Traditional Chinese Medicine Key Discipline of Traditional Chinese Medicine Diagnosis of Traditional Chinese Medicine(No.1242000309)。
Objective:To study the effect of Tongqiao Huoxue Decoction combined with butylphthalide soft capsules on acute ischemic stroke and its effect on serum vascular endothelial growth factor(VEGF).Methods:There are 76 pati...
关键词:Tongqiao Huoxue Decoction BUTYLPHTHALIDE Acute Ischemic Stroke EFFICACY VEGF 
To investigate the effects of butylphthalide on reducing neuronal apoptosis in rats with cerebral infarction by inhibiting the JNK/P38 MAPK signaling pathway
《Journal of Hainan Medical University》2020年第8期7-11,共5页Yan Sun Yuan Zou Qian Xue Xiao-Qin Wang 
Key research project of medical science of Hubei province
Objective:To investigate the effects of butylphthalide on reducing neuronal apoptosis in rats with cerebral infarction by inhibiting the JNK/P38 MAPK signaling pathway.Methods:Forty-eight SD male rats were divided int...
关键词:Cerebral infarction BUTYLPHTHALIDE Nerve cells Infarct size JNK/P38 MAPK signaling pathway 
Effect of dl-3-n-butylphthalide on infarction volume in animal models of ischemic stroke:A meta-analysis
《World Journal of Meta-Analysis》2019年第7期358-372,共15页Di Luan Zheng-Yu Wu Yuan-Xiang Zhang Li-Li Yuan Yang Xu Zhao-Hu Chu Ling-Song Ma Ya-Ping Wang Shou-Cai Zhao 
the National Natural Science Foundation of China,NO.81701161.
BACKGROUND Ischemic stroke is a frequently-occurring disease in the elderly and characterized by high morbidity and mortality.Dl-3-n-butylphthalide(NBP),a synthetic compound based on natural celery seeds,has potential...
关键词:BUTYLPHTHALIDE Animal model ISCHEMIC stroke META-ANALYSIS 
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