supported by National Science Foundation of China(82172217);Fundamental Science(Natural Science)Research Project of the Jiangsu Higher Education Institutions of China(No.21KJB360016);Natural Science Foundation of Nanjing University of Chinese Medicine(No.XZR2020069).
Acute and chronic wound infection has become a major worldwide healthcare burden leading to significantly high morbidity and mortality.The underlying mechanism of infections has been widely investigated by scientist,w...
funded by an EMBO Long-term Fellowship ALTF 767-2017.
Bacteriophages(hence termed phages)are viruses that target bacteria and have long been considered as potential future treatments against antibiotic-resistant bacterial infection.However,the molecular nature of phage i...
supported by the National Natural Science Foundation of China(NSFC 31701725 and 31950410562);the National Key R&D Program of China(No.2018YEE0101900).
Many studies have shown the efficacy of phage therapy in reducing gastrointestinal pathogens.However,it is unclear whether phages can successfully colonize the gut when administered in an adequate amount for a long ti...
Abundant virus-like particles were concentrated from large-volume samples from two hot springs. Both addition of viral concentrates and addition of samples induced by addition of mitomycin-C changed patterns of carbon...
The emergence of multidrug-resistant bacterial pathogens forced us to consider the phage therapy as one of the possible alternative approaches to treatment. The purpose of this paper is to consider the conditions for ...
Supported by The NIH-AREA Grant,No.1R15GM52696-01;the NSF-RUI Grant,No.DMB-8608480;the Howard Hughes Medical Research Institute(two grants to the PLNU Biology Department);Research Associates of PLNU(a 300 member alumni support group);the PLNU Administration
AIM: To probe the organizational structure of the adsorption apparatus of bacteriophage epsilon 15(E15) using genetic and biochemical methodology METHODS: Hydroxylamine was used to create nonsense mutants of bacteriop...
Supported by the MIUR and Progetto Strategico Oncologia "Terapia Preclinica Moleculare Oncologia" MIUR-CNR
AIM: To investigate the association of cyclooxygenase-2 (COX-2) expression with angiogenesis and the number and type of inflammatory cells (macrophages/Kupffer cells; mast cells) within primary hepatocellular car...
Both the antigen presenting ability and the cytotoxicity of macrophages can be enhanced by GMCSF gene transfer. In the present study, the therapeutic effect of intratumoral injection with GMCSF genemodified allogenic ...
The effects of Lobenzarit disodium (CCA) upon the activity of interleukin-1(IL-1) of peritoneal macrophages(PMΦ)in normal and in adjuvant arthritis AA) rats and on the release of hydrogen peroxide(H_2O_2)of rat perit...