METAPHASE

作品数：24被引量：26H指数：3
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相关作者：朱湘毅唐泉秦钜晏马登哲李玉家更多>>
相关机构：上海交通大学中国科学技术大学四川农业大学南京大学医学院附属鼓楼医院更多>>
相关期刊：《海外英语》《Tsinghua Science and Technology》《Frontiers of Medicine》《Journal of Cancer Therapy》更多>>
相关基金：国家自然科学基金上海市科学技术发展基金四川省青年科技基金更多>>
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ChromTR:chromosome detection in raw metaphase cell images via deformable transformers
《Frontiers of Medicine》2024年第6期1100-1114,共15页Chao Xia Jiyue Wang Xin You Yaling Fan Bing Chen Saijuan Chen Jie Yang 
supported by the National Natural Science Foundation of China(No.81670137);SJTU Trans-med Awards Research(No.20220102);State Key Laboratory of Medical Genomics Support(No.201802)。
Chromosome karyotyping is a critical way to diagnose various hematological malignancies and genetic diseases,of which chromosome detection in raw metaphase cell images is the most critical and challenging step.In this...
关键词：chromosome detection deformable transformer metaphase cell image distribution reasoning 
Melatonin improves the first cleavage of parthenogenetic embryos from vitrified-warmed mouse oocytes potentially by promoting cell cycle progression被引量：1
《Journal of Animal Science and Biotechnology》2022年第1期106-122,共17页Bo Pan Izhar Hyder Qazi Shichao Guo Jingyu Yang Jianpeng Qin Tianyi Lv Shengqin Zang Yan Zhang Changjun Zeng Qingyong Meng Hongbing Han Guangbin Zhou 
supported by the National Natural Science Foundation of China(grant no.32072735,31572398);the Natural Science Fund of Qinghai Province(2020-ZJ-902);by the China Agriculture Research System(grant no.CARS-36).
Background:This study investigated the effect of melatonin(MT)on cell cycle(G1/S/G2/M)of parthenogenetic zygotes developed from vitrified-warmed mouse metaphase II(MII)oocytes and elucidated the potential mechanism of...
关键词：Cell cycle Cleavage rate MELATONIN MetaphaseⅡoocyte Parthenogenetic activation VITRIFICATION 
Effects of vitrification and cryostorage duration on single-cell RNA-Seq profiling of vitrified-thawed human metaphase Ⅱ oocytes被引量：8
《Frontiers of Medicine》2021年第1期144-154,共11页Ying Huo Peng Yuan Qingyuan Qin Zhiqiang Yan Liying Yan Ping Liu Rong Li Jie Yan Jie Qiao 
supported by grants from the National Key Research and Development Program(Nos.2017YFC1002000,2018YFC1004001,and 2016YFC1000600);the National Natural Science Foundation of China(Nos.81571386 and 31429004);the Capital Health Development Research Project(No.2018-2-4095).
Oocyte cryopreservation is widely used for clinical and social reasons.Previous studies have demonstrated that conventional slow-freezing cryopreservation procedures,but not storage time,can alter the gene expression ...
关键词：human metaphaseⅡoocyte VITRIFICATION cryostorage duration single-cell RNA-Seq lncRNA 
Analyze the rules of Chinese herbal of Professor Xiong Lu in treating metaphase and advanced lung cancer by data mining
《TMR Integrative Medicine》2017年第2期37-44,共8页Dao-Rui Hou Li Zhu Ya-Hui Peng Lu Xiong 
Objective： To analyze the experience of chief physician Xiong Lu in treating metaphase and advanced lung cancer through using TCM inheritance support system （V2.5）. Methods： Collecting the prescriptions used for m...
关键词：Metaphase and advanced lung cancer Data mining Fuzheng Peiben （Therapy for support Zheng-qi to propup root） Toxic drugs Incompatible medicaments 
Moderate Hyperthermia Induces Apoptosis in Metaphase-Arrested Cells But Not in Interphase Hela Cells
《Advances in Biological Chemistry》2016年第3期126-139,共14页James R. Paulson Agnes Kecskeméti Kresch Peter W. Mesner 
Metaphase-arrest agents and hyperthermia are both known to be capable of inducing apoptosis, and they have been used, separately, in cancer treatments. Here, we have examined whether the two treatments together may ha...
关键词：APOPTOSIS Caspase Heat Treatment H-Hela HYPERTHERMIA Metaphase-Arrest MITOSIS NOCODAZOLE Paclitaxel zVAD-fmk 
No effect of exogenous melatonin on development of cryopreserved metaphase Ⅱ oocytes in mouse
《Journal of Animal Science and Biotechnology》2015年第4期388-394,共7页Wei Li Keren Cheng Yue Zhang Qinggang Meng Shi'en Zhu Guangbin Zhou 
supported in part by the National genetically modified organisms breeding major projects(Grant No.2014ZX0800802B);the fund for Backup Candidate of Academic Technology Leaders in Sichuan Province
Background： This study was conducted to investigate effect of exogenous melatonin on the development of mouse mature oocytes after cryopreservation. Results： First, mouse metaphase II （MII） oocytes were vitrified ...
关键词：Gene expression Melationin Mouse oocyte Parthenogenetic activation vitrificantion 
Neoplastic-Like CELL Changes of Normal Fibroblast Cells Associated with Evolutionary Conserved Maternal and Paternal Genomic Autonomous Behavior (Gonomery)被引量：7
《Journal of Cancer Therapy》2014年第9期860-877,共18页Kirsten H. Walen 
The present comparative review discusses conservation of early evolutionary, relic genetics in the genome of man, which determine two different mechanistic reductive division systems expressed by normal, human diploid...
关键词：CYTOGENETICS Pathologic Cytology ENDOMITOSIS Division Skewedness Pathological Mitosis METAPHASE Rosettes HOMOZYGOUS LOH Growth Pattern Nutrition Amino Acid 
Spontaneous and Bleomycin-Induced <i>γ</i>H2AX Signals in CHO9 Metaphase Chromosomes
《Advances in Bioscience and Biotechnology》2014年第7期603-616,共14页María Vittoria Di Tomaso Silvia Basso Laura Lafon-Hughes Gustavo Saona Beatriz López-Carro Ana Laura Reyes-ábalos Pablo Liddle 
In eukaryotes, a cascade of events named DNA damage response (DDR) has evolved to handle DNA lesions. DDR engages the recruitment of signaling, checkpoint control, repair and chromatin remodeling protein complexes, al...
关键词：H2AX Phosphorylation on Serine 139 γH2AX SIGNALS METAPHASE Chromosomes Homologous Chromosome Regions CHO9 Chinese HAMSTER Cell Line 
Haploidization of Human Diploid Metaphase Cells: Is This Genome Reductive Mechanism Opperational in Near-Haploid Leukemia?被引量：2
《Journal of Cancer Therapy》2014年第1期101-114,共14页Kirsten H. Walen 
The present study presents cytogenetics/cytology of haploidization in the origin of a new, fast growing diploid, small cell-type (F-dPCs). The sequence of events was haploid groupings of the chromosomes in normal, hum...
关键词：NUTRITIONAL Replicative Stress Amino Acid Glutamine Chromosome/Genomic Aberrations Small CELLS Proliferative Advantage Loss of HETEROZYGOSITY GENOMIC Doubling Uniparentaldisomy ENDOREPLICATION GENOMIC Territories Nuclear Roundness NUTRITIONAL Insufficiency Autophagy 
卵母细胞成熟障碍4例与同期卵母细胞大部分不成熟患者比较分析
《中国优生与遗传杂志》2013年第12期134-136,共3页王磊 邵小光 司远彬 
目的分析4例体外受精-胚胎移植(IVF-ET)患者共8个辅助助孕周期,全部73个卵母细胞均处于GV、Metaphase I期的可能原因。并与同期13例IVF-ET患者比较分析,比较组患者>50%卵母细胞处于GV、Metaphase I期。方法回顾分析本中心12年辅助助孕...
关键词：卵母细胞 减数分裂 METAPHASE I停滞 GV期停滞 不孕 卵母细胞成熟障碍 
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