云南高校图书馆联盟文献共享服务平台- NOCODAZOLE

NOCODAZOLE: 作品数：16被引量：24H指数：3; 导出分析报告; 相关作者：郭双平晏伟严晓昱张志培成胜权更多>>; 相关机构：第四军医大学江西省儿童医院上海交通大学南昌大学更多>>; 相关期刊：《天津医药》《Acta Pharmacologica Sinica》《Advances in Biological Chemistry》《上海交通大学学报（医学版）》更多>>; 相关基金：国家自然科学基金江西省科技厅科技支撑计划项目江西省教育厅科技计划项目国家现代农业产业技术体系建设项目更多>>

Role of microtubule dynamics in Wallerian degeneration and nerve regeneration after peripheral nerve injury被引量：1: 《Neural Regeneration Research》2022年第3期673-681,共9页Jingmin Liu Lixia Li Ying Zou Lanya Fu Xinrui Ma Haowen Zhang Yizhou Xu Jiawei Xu Jiaqi Zhang Mi Li Xiaofang Hu Zhenlin Li Xianghai Wang Hao Sun Hui Zheng Lixin Zhu Jiasong Guo; supported by the National Natural Science Foundation of China,Nos.82071386 (to JS),81870982 (to JS)&81571182 (to JS);the National Key Basic Research Program of China,No.2014CB542202 (to JS);the Program for Changjiang Scholars and Innovative Research Team in University of China,No.IRT-16R37 (to JS);Key Research&Development Program of Guangzhou Regenerative Medicine and Health Guangdong Laboratory of China,No.2018GZR110104008 (to HZ);Research Grant of Guangdong Province Key Laboratory of Psychiatric Disorders of China,No.N201904 (to JS);Natural Science Foundation of Guangdong Province of China,No.2017A030312009 (to JS)。; Wallerian degeneration,the progressive disintegration of distal axons and myelin that occurs after peripheral nerve injury,is essential for creating a permissive microenvironment for nerve regeneration,and involves cy...; 关键词：AXON DEMYELINATION microtubule dynamics nerve regeneration NOCODAZOLE PACLITAXEL peripheral nerve injury Schwann cell Wallerian degeneration

Quantifying 3D cell-matrix interactions during mitosis and the effect of anticancer drugs on the interactions被引量：4: 《Nano Research》2021年第11期4163-4172,共10页Yongman Liu Jianye Wang Yong Su Xiaohai Xu Hong Liu Kainan Mei Shihai Lan Shubo Zhang Xiaoping Wu Yunxia Cao Qingchuan Zhang Shangquan Wu; The authors gratefully acknowledge financial support from the National Natural Science Foundation of China(Nos.11872355,11627803,12072339,and 11872354);the Strategic Priority Research Program of the Chinese Academy of Science(No.XDB22040502).; The mechanical force between cells and the extracellular microenvironment is crucial to many physiological processes such as cancer metastasis and stem cell differentiation. Mitosis plays an essential role in all thes...; 关键词：cell division traction force PACLITAXEL NOCODAZOLE

A Method for Astral Microtubule Tracking in Fluorescence Images of Cells Doped with Taxol and Nocodazole: 《Advances in Molecular Imaging》2019年第4期60-86,共27页Marilena Varrecchia Joshua Levine Gabriella Olmo Marco Grangetto Marta Gai Ferdinando Di Cunto; In this paper, we describe an algorithm that performs automatic detection and tracking of astral microtubules in fluorescence confocal images. This sub-population of microtubules only exists during and immediately bef...; 关键词：Medical Diagnostic Imaging FLUORESCENCE CONFOCAL Microscopy Image Segmentation MICROTUBULES

An RNA-binding protein, RNP-1, protects microtubules from nocodazole and localizes to the leading edge during cytokinesis and cell migration in Dictyostelium cells: 《Acta Pharmacologica Sinica》2016年第11期1449-1457,共9页Thu NGO Xin MIAO Douglas N ROBINSON Qiong-qiong ZHOU; Aim： RNA-binding proteins are a large group of regulators （800-1000 in humans）, some of which play significant roles in mRNA local translation. In this study, we analyzed the functions of the protein RNP-1, which w...; 关键词：CYTOKINESIS MICROTUBULES cell migration NOCODAZOLE RNA binding protein poly（A）-binding protein Dictyostelium cells

Moderate Hyperthermia Induces Apoptosis in Metaphase-Arrested Cells But Not in Interphase Hela Cells: 《Advances in Biological Chemistry》2016年第3期126-139,共14页James R. Paulson Agnes Kecskeméti Kresch Peter W. Mesner; Metaphase-arrest agents and hyperthermia are both known to be capable of inducing apoptosis, and they have been used, separately, in cancer treatments. Here, we have examined whether the two treatments together may ha...; 关键词：APOPTOSIS Caspase Heat Treatment H-Hela HYPERTHERMIA Metaphase-Arrest MITOSIS NOCODAZOLE Paclitaxel zVAD-fmk

MCL-1和FBW7蛋白在纺锤丝毒性药物诱导的乳腺癌多倍体中的表达及临床意义被引量：3: 《天津医药》2015年第9期970-974,共5页张倩袁碧波王彦许毅; 国家自然科学基金资助项目(30872969); 目的探讨MCL-1和FBW7蛋白在纺锤丝毒性药物诱导的乳腺癌多倍体中的表达及临床意义。方法 (1)以纺锤丝毒性药物Nocodazole处理人乳腺癌MDA-MB-231细胞,显微镜下观察细胞形态学变化,并于0、6、12、24、48及72 h收获细胞,流式细胞术检测细...; 关键词：乳腺肿瘤多倍性体外研究 MCL-1 FBW7 纺锤丝毒性药物 NOCODAZOLE 索拉非尼

miR-21与Nocodazole联合作用对小鼠成肌细胞C2C12周期的影响: 《中国畜牧杂志》2015年第1期10-14,共5页刘会杰敖红白立景王志军邢凯王楚端; 北京市现代农业产业技术创新团队(25019126); 观察miR-21与Nocodazole联合作用对小鼠成肌细胞C2C12周期的影响。分别以0、200、300、400、500、600 nmol/L Nocodazole处理C2C12细胞24 h,流式细胞仪检测细胞周期,间接免疫染色激光共聚焦显微镜观察细胞有丝分裂器α-微管蛋白(α-tubu...; 关键词：NOCODAZOLE MIR-21 C2C12 周期小鼠

不同浓度秋水仙素和nocodazole对绒山羊成纤维细胞周期同步化的影响被引量：3: 《中国畜牧兽医》2013年第9期136-139,共4页杨惠茹肖红梅蔡婷俎红丽于新蕾刘志红李金泉王志新; 国家863计划(2013AA102506);国家自然科学基金(31072005;31272421);国家农业部现代农业产业技术体系(CARS-40-05); 本试验旨在探索更加优化的条件,使绒山羊成纤维细胞经处理后更多的处于有丝分裂G2/M期。本研究分别采用秋水仙素和nocodazole试剂对绒山羊成纤维细胞进行周期同步化处理,用流式细胞仪检测G2/M期的细胞数量并进行比对,观测最佳作用浓度...; 关键词：绒山羊成纤维细胞秋水仙素 NOCODAZOLE 细胞周期同步化流式细胞仪

Structural Chromosome Unstability Following Combined Effects of Carbon Ions and Nocodazole: 《IMP & HIRFL Annual Report》2011年第1期142-142,共1页Li Ping Li Qiang Jin Xiaodong Wu Qingfeng; 关键词：染色体不稳定性碳离子 DNA损伤结构有丝分裂过程双链断裂细胞周期线粒体

Nocodazole对骨肉瘤MG-63细胞增殖凋亡的影响及机制研究被引量：2: 《中国药物与临床》2011年第2期140-143,共4页贾鹏吕智刘小丽冯毅薛小云; 山西省自然科学基金(2007011112); 目的以细胞有丝分裂阻滞剂Nocodazole为诱导物,诱导骨肉瘤MG-63细胞凋亡,并进行生物化学指标的检测。方法首先,观察1nmol/L～10μmol/L递增浓度的Nocodazole对MG-63细胞的作用,然后选取10,50,100,500nmol/L4个浓度诱导凋亡,通过噻唑蓝(M...; 关键词：骨肉瘤甲酸酯类细胞增殖细胞凋亡

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