CYTOKINESIS

作品数：36被引量：80H指数：6
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相关领域：生物学医药卫生更多>>
相关作者：吕炳建来茂德蔡雪戴谷李静更多>>
相关机构：浙江大学中国科学院植物研究所内蒙古大学首都师范大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划国家教育部博士点基金北京市自然科学基金更多>>
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NudCL2 is required for cytokinesis by stabilizing RCC2 with Hsp90 at the midbody
《Protein & Cell》2024年第10期766-782,共17页Xiaoyang Xu Yuliang Huang Feng Yang Xiaoxia Sun Rijin Lin Jiaxing Feng Mingyang Yang Jiaqi Shao Xiaoqi Liu Tianhua Zhou Shanshan Xie Yuehong Yang 
supported by the National Natural Science Foundation of China(Nos.32070709,32270771,and U21A20197);the National Key Research and Development Program of China(Nos.2019YFA0802202);the Higher Education Discipline Innovation Project(also known as the111 Project)(Nos.B13026).
Cytokinesis is required for faithful division of cytoplasmic components and duplicated nuclei into two daughter cells.Midbody,a protein-dense organelle that forms at the intercellular bridge,is indispensable for succe...
关键词：CYTOKINESIS MIDBODY NudCL2 HSP90 RCC2 
A novel variant associated with refractory lymphopenia in systemic lupus erythematosus:Dedicator of cytokinesis 2 gene c.2883_2886dup
《Rheumatology & Autoimmunity》2024年第3期180-182,共3页Minghua Huang Yaqi Zhao Wei Xu Zhenzhen Ma Yanyan Bai Qingrui Yang 
Natural Science Foundation of Shandong Province(No.ZR2022MH016);National Natural Science Foundation of China(Youth fund project,No.82201994).
To the Editor,Genetic and phenotypic heterogeneity present challenges for the diagnosis and personalized treatment of systemic lupus erythematosus(SLE).1 Leukopenia,a common clinical presentation of SLE,can vary in se...
关键词：ERYTHEMATOSUS LUPUS diagnosis 
AtMAC stabilizes the phragmoplast by crosslinking microtubules and actin filaments during cytokinesis
《Journal of Integrative Plant Biology》2023年第8期1950-1965,共16页Pingzhou Du Yu Liu Lu Deng Dong Qian Xiuhua Xue Ting Yang Tonghui Li Yun Xiang Haiyun Ren 
supported by grants from the National Natural Science Foundation of China(92254303 and 32170335)to Haiyun Ren and(32200272)to Pingzhou Du;the start-up fund of Beijing Normal University at Zhuhai(310432102)to Pingzhou Du。
The phragmoplast,a structure crucial for the completion of cytokinesis in plant cells,is composed of antiparallel microtubules(MTs)and actin filaments(AFs).However,how the parallel structure of phragmoplast MTs and AF...
关键词：actin filaments AtMAC CYTOKINESIS PHRAGMOPLAST MICROTUBULES 
Eczema herpeticum vs dermatitis herpetiformis as a clue of dedicator of cytokinesis 8 deficiency diagnosis:A case report
《World Journal of Clinical Cases》2022年第29期10735-10741,共7页Amer Alshengeti 
BACKGROUND Dedicator of cytokinesis 8(DOCK 8) deficiency,also known as autosomal recessive hyper immunoglobulin E(IgE) syndrome,is a combined immunodeficiency disease that was first recognized in 2009.It is caused by ...
关键词：Immunoglobulin E Whole-exome sequencing INFECTIONS Dedicator of cytokinesis 8 Case report 
Targeting cytokinesis bridge proteins to kill high-CIN type tumors
《Fundamental Research》2021年第6期752-766,共15页Bingteng Xie Xiaoling Liang Wei Yue Jihong Ma Xinyu Li Na Zhang Pan Wang Chang Liu Xiaomeng Shi Jie Qiao Peng Zou Mo Li 
supported by the National Natural Science Foundation of China(NSFC)(Grants No.81672610,81521002,81871160)to ML,and by the“Clinic+X”program(to ML)of Peking University.
As a common feature of tumors,chromosomal instability(CIN)not only forces carcinomatous evolution,but also loads cancer cells with extra pressure through a robust imbalance of genome patterning that may be used for ca...
关键词：Cytokinesis bridge proteome APEX2 High-CIN tumors Micronuclei cGAS 
MS1 is essential for male fertility by regulating the microsporocyte cell plate expansion in soybean被引量：8
《Science China(Life Sciences)》2021年第9期1533-1545,共13页Xiaolong Fang Xiaoyuan Sun Xiangdong Yang Qing Li Chunjing Lin Jie Xu Wenjun Gong Yifan Wang Lu Liu Limei Zhao Baohui Liu Jun Qin Mengchen Zhang Chunbao Zhang Fanjiang Kong Meina Li 
supported by the National Natural Science Foundation of China(32072084,31871648,and 31971969)。
Male sterility is an essential trait in hybrid seed production,especially for monoclinous and autogamous food crops.Soybean male-sterile ms1 mutant has been known for more than 50 years and could be instrumental in ma...
关键词：SOYBEAN male sterility MS1 KINESIN CYTOKINESIS hybrid breeding 
Cytogenetic biodosimetry for radiation accidents in China被引量：7
《Radiation Medicine and Protection》2020年第3期133-139,共7页Lin Han Yu Gao Ping Wang Yumin Lyu 
This work was supported by Key Science and Technology Project of Henan Province,China,IDs:142102310086;Medical Science and Technology Reseach of Henan Province,China,IDs:LHGJ20190815。
Cytogenetic indicators,especially dicentric chromosomes,have been globally considered the gold standard of biological dose estimation for more than 60 years.The application of these indicators to biological dose estim...
关键词：BIODOSIMETRY CYTOGENETICS Chromosomal aberrations Cytokinesis-block micronuclei Nucleoplasmic bridges Premature condensation chromosome ring 
Phyllanthus emblica Linn.fruit extract potentiates the anticancer efficacy of mitomycin C and cisplatin and reduces their genotoxicity to normal cells in vitro被引量：12
《Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)》2017年第12期1031-1045,共15页Xi-han GUO Juan NI Jing-lun XUE Xu WANG 
Project supported by the National Natural Science Foundation of China(Nos.31260268 and 31560307)
Objective： Fruit of Phyllanthus emblica Linn. （PE） is widely consumed as a functional food and used as a folk medicine due to its remarkable nutritional and pharmacological effects. Mitomycin C （MMC） and cisplat...
关键词：Phyllanthus emblica Mitomycin C CISPLATIN Genomic instability Cytokinesis-block micronucleus assay 
An RNA-binding protein, RNP-1, protects microtubules from nocodazole and localizes to the leading edge during cytokinesis and cell migration in Dictyostelium cells
《Acta Pharmacologica Sinica》2016年第11期1449-1457,共9页Thu NGO Xin MIAO Douglas N ROBINSON Qiong-qiong ZHOU 
Aim： RNA-binding proteins are a large group of regulators （800-1000 in humans）, some of which play significant roles in mRNA local translation. In this study, we analyzed the functions of the protein RNP-1, which w...
关键词：CYTOKINESIS MICROTUBULES cell migration NOCODAZOLE RNA binding protein poly（A）-binding protein Dictyostelium cells 
The Membrane-Associated Sec1/Munc18 KEULE is Required for Phragmoplast Microtubule Reorganization During Cytokinesis in Arabidopsis被引量：1
《Molecular Plant》2016年第4期528-540,共13页Alexander Steiner Lin Muller Katarzyna Rybak Vera Vodermaier Eva Facher Martha Thellmann Raksha Ravikumar Gerhard Wanner Marie-Theres Hauser Farhah F. Assaad 
Cytokinesis, the partitioning of the cytoplasm following nuclear division, requires extensive coordination between membrane trafficking and cytoskeletal dynamics. In plants, the onset of cytokinesis is characterized b...
关键词：CYTOKINESIS cell plate phragmoplast microtubule KEULE KNOLLE PLEIADE/MAP65-3 
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