SIMVASTATIN

作品数：146被引量：355H指数：10
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相关机构：大连医科大学苏州大学吉林大学大连医科大学附属第二医院更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划大连市科技计划项目河北省自然科学基金更多>>
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Simvastatin/hydrogel-loaded 3D-printed titanium alloy scaffolds suppress osteosarcoma via TF/NOX2-associated ferroptosis while repairing bone defects被引量：2
《Bioactive Materials》2024年第4期463-465,共3页Zehao Jing Wanqiong Yuan Jiedong Wang Renhua Ni Yu Qin Zhinan Mao Feng Wei Chunli Song Yufeng Zheng Hong Cai Zhongjun Liu 
supported by National Natural Science Foundation of China(grant number 82272456 and 82202748);China Postdoctoral Science Foundation(grant number 2022M720297).
The authors regret to inform that the image in Fig.8 G was selected by mistake.The correct form of this figure is as below.The authors apologize for any inconvenience we caused and state that this correction does not ...
关键词：alloy titanium correction 
Simvastatin/hydrogel-loaded 3D-printed titanium alloy scaffolds suppress osteosarcoma via TF/NOX2-associated ferroptosis while repairing bone defects被引量：1
《Bioactive Materials》2024年第3期223-241,I0002-I0004,共19页Zehao Jing Wanqiong Yuan Jiedong Wang Renhua Ni Yu Qin Zhinan Mao Feng Wei Chunli Song Yufeng Zheng Hong Cai Zhongjun Liu 
supported by National Natural Science Foundation of China(grant number 82272456 and 82202748);China Postdoctoral Science Foundation(grant number 2022M720297).
Postoperative anatomical reconstruction and prevention of local recurrence after tumor resection are two vital clinical challenges in osteosarcoma treatment.A three-dimensional(3D)-printed porous Ti6Al4V scaffold(3DTi...
关键词：3D-printed titanium alloy IMPLANT SIMVASTATIN OSTEOSARCOMA Ferroptosis 
Enhanced osseointegration of drug eluting nanotubular dental implants: An in vitro and in vivo study
《Bioactive Materials》2023年第10期432-447,共16页Pankaj Chauhan Alok Srivastava Pooja Bhati Manish Chaturvedi Vinay Patil Sriram Kunnoth Nisha Kumari Vedpal Arya Madhur Pandya Mohit Agarwal Smiti Bhardwaj Farrukh Faraz Sanjay Chauhan Mahesh Verma Veena Koul Naresh Bhatnagar 
Faster and predictable osseointegration is crucial for the success of dental implants, especially in patients with compromised local or systemic conditions. Despite various surface modifications on the commercially av...
关键词：Titanium BIOCOMPATIBILITY SIMVASTATIN NANOTUBE Micro CT HISTOPATHOLOGY Nanoscale 
Simvastatin-hydroxyapatite coatings prevent biofilm formation and improve bone formation in implant-associated infections被引量：1
《Bioactive Materials》2023年第3期44-56,共13页Tiantong Sun Jie Huang Wang Zhang Xuanqi Zheng Hong Wang Jing Liu Huijie Leng Wanqiong Yuan Chunli Song 
National Key Research and Development Program[Grant No.2020YFC2009004];National Natural Science Foundation of China(Project No.81874010);PKU-Baidu Fund(Grant No.2020BD014).
Implant-associated infections(IAIs)caused by biofilm formation are the most devastating complications of orthopedic surgery.Statins have been commonly and safely used drugs for hypercholesterolemia for many years.Here...
关键词：Implant-associated infections SIMVASTATIN Antibacterial BIOFILM OSTEOGENESIS 
Synergistic effects of magnesium ions and simvastatin on attenuation of high-fat diet-induced bone loss被引量：6
《Bioactive Materials》2021年第8期2511-2522,共12页Bingyang Dai Xu Li Jiankun Xu Yuwei Zhu Le Huang Wenxue Tong Hao Yao Dick Ho-kiu Chow Ling Qin 
supported by Theme-based Research Scheme from RGC-Hong Kong(No.T13-402/17N);partially supported by Health and Medical Research Fund(17180671);National Natural Science Foundation of China(81802152).
Introduction:Magnesium(Mg)has a prophylactic potential against the onset of hyperlipidemia.Similar to statin,Mg is recommended as lipid-lowering medication for hypercholesterolemia and concomitantly exhibits an associ...
关键词：OBESITY Bone loss MAGNESIUM SIMVASTATIN Trabecular bone CHOLESTEROL 
Enhanced osteogenesis and therapy of osteoporosis using simvastatin loaded hybrid system被引量：7
《Bioactive Materials》2020年第2期348-357,共10页Tao Wu Jing Sun Lei Tan Qi Yan Lei Li Liangwen Chen Xiangmei Liu Shi Bin 
supported by National Natural Science Foundation of China(Grant 81600906);the Fundamental Research Funds for the Central University of China(No.2042018kf0108).
Postmenopausal osteoporosis is a common chronic dynamic bone disorder,caused by estrogen deficiency.To address this issue,we constructed a controlled drug-release system composed of poly(N-isopropylacrylamide)brush mo...
关键词：OSTEOGENESIS OSTEOPOROSIS Mesoporous hydroxyapatite Bone marrow stromal cells Drug release 
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