LYASE

作品数:58被引量:163H指数:7
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相关领域:医药卫生农业科学更多>>
相关作者:刘永军孙维佳李文旭胡天晓李苑更多>>
相关机构:山东大学济宁学院桂林医学院附属医院中南大学更多>>
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相关基金:国家自然科学基金湖北省自然科学基金北京市自然科学基金国家教育部博士点基金更多>>
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  • 学科=医药卫生—肿瘤x
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Bioinformatics analysis and experimental validation of cystathionine-gamma-lyase as a potential prognosis biomarker in hepatocellular carcinoma被引量:1
《BIOCELL》2024年第3期463-471,共9页YANAN MA SHANSHAN WANG HUIGUO DING 
This study was supported by Beijing Municipal Science&Technology Commission to Huiguo Ding(Z221100007422002);Beijing Hospitals Authority Youth Programme to Shanshan Wang(QML20211701).
Background:Hepatocellular carcinoma(HCC)is a common malignant tumor with poor prognosis and high mortality worldwide.Although cystathionine-gamma-lyase(CSE)plays an important role in the development of multiple tumors...
关键词:Hepatocellular carcinoma Cystathionine-gamma-lyase Hydrogen sulfide PROGNOSIS Apoptosis 
A comprehensive review on microbial hyaluronan-degrading enzymes:from virulence factors to biotechnological tools
《Bioresources and Bioprocessing》2024年第1期1492-1514,共23页Jia-Yu Jiang Dai Xue Jin-Song Gong Qin-Xin Zheng Yue-Sheng Zhang Chang Su Zheng-Hong Xu Jin-Song Shi 
financially supported by the National Key Research and Development Program of China(No.2021YFC2100900);the National Natural Science Foundation of China(No.32171261);the Taishan Industry Leading Talent of Shandong Province(No.tscx202211017);the Postgraduate Research&Practice Innovation Program of Jiangsu Province(No.KYCX23_2575).
Hyaluronan(HA),a natural high molecular weight polysaccharide,has extensive applications in cosmetology and medical treatment.Hyaluronan-degrading enzymes(Hyals)act as molecular scissors that cleave HA by breaking the...
关键词:Hyaluronan-degrading enzymes Hyaluronan lyase HYALURONIDASE Host invasion Disease development ANTI-BACTERIA Cancer therapy Hyaluronan degradation Hyaluronan detection 
S1P lyase在肝癌中的表达及对其预后的影响被引量:2
《中国实验诊断学》2020年第6期887-891,共5页邱志东 王雪红 孙维佳 金俊飞 
广东省自然科学基金资助项目(2018A0303130296)。
目的探讨S1P lyase在肝癌中的表达情况,及其对肝癌预后的影响。方法选取桂林医学院附属医院54例肝细胞癌患者,real-time PCR分析S1P lyase在54对肝细胞癌癌组织及癌旁组织中的表达,运用统计学方法探讨S1P lyase表达与肝癌临床病理特征...
关键词:S1P lyase 肝癌 生物信息学 预后 
Therapeutic importance of hydrogen sulfide in age-associated neurodegenerative diseases被引量:4
《Neural Regeneration Research》2020年第4期653-662,共10页Rubaiya Tabassum Na Young Jeong Junyang Jung 
supported by Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Science, ICT and Future Planning, No. 2018R1A2B6001123 (to NYJ), No. 2018R1D1A1B07040282 (to JJ)
Hydrogen sulfide(H2S)is a gasotransmitter that acts as an antioxidant and exhibits a wide variety of cytoprotective and physiological functions in age-associated diseases.One of the major causes of age-related disease...
关键词:3-mercaptopyruvate SULFURTRANSFERASE aging antioxidant cystathionineβ-synthase cystathionineγ-lyase GLUTATHIONE hydrogen sulfide NEURODEGENERATIVE disease oxidative stress reactive oxygen species 
Combinatorial Enzyme Approach to Produce Oligosaccharides of Diverse Structures for Functional Screen被引量:1
《Advances in Enzyme Research》2018年第2期11-20,共10页Dominic W. S. Wong Doris Feng, Sarah Batt William Orts 
Combinatorial chemistry has been a focus of research activity in modern drug discovery and biotechnology. It is a concept by which a vast library of molecular diversity is synthesized and screened for target propertie...
关键词:Combinatorial ENZYME POLYGALACTURONASE Pectate LYASE PECTIN OLIGOSACCHARIDES 
Pharmacological Prospects of Oxygenated Abietane-Type Diterpenoids from <i>Taxodium distichum</i>Cones
《Advances in Biological Chemistry》2014年第2期109-115,共7页Norihisa Kusumoto Nobuhiro Aburai Tatsuya Ashitani Koetsu Takahashi Ken-ichi Kimura 
Eight naturally occurring diterpenoids, including 6,7-dehydroroyleanone, taxodal, taxodione, salvinolone, 14-deoxycoleon U, 5,6-dehydrosugiol, sandaracopimaric acid, and xanthoperol were isolated from Taxodium distich...
关键词:ABIETANE Diterpenoid CONIFER Cone Antibacterial Activity 17α-Hydroxylase/C17 20-Lyase Prolyl Oligopeptidase Cytotoxicity 
Enzymes of Phenylpropanoid Metabolism Involved in Strengthening the Structural Barrier for Providing Genotype and Stage Dependent Resistance to Karnal Bunt in Wheat
《American Journal of Plant Sciences》2012年第2期261-267,共7页Shalini Purwar Sanjay Mohan Gupta Anil Kumar 
The role of lignifications and enzymes involved in the phenylpropanoid (PP) biosynthesis i.e. phenylalanine ammonia lyase (PAL), Peroxidase (POD), Polyphenol oxidase (PPO) in providing resistance to Karnal Bunt (KB) d...
关键词:Karnal Blunt Peroxidase PHENYLALANINE Ammonia LYASE PHENYLPROPANOID Metabolism POLYPHENOL OXIDASE Tilletia Indica WHEAT 
EFFECT OF ACTINOMYCIN D AND CYCLOHEXIMIDE ON THE FORMATION OF PEROXIDASE DURING EMBRYOGENESIS AND GERMINATION OF RICE(ORYZA SATIVA L.)
《Chinese Science Bulletin》1980年第11期956-959,共4页朱治平 汪曼丽 沈瑞娟 唐锡华 
Various plants have their characters developed successively in different developmental stages. From the view of point of molecular biology, the course of plant development is also a time course of selective expression...
关键词:developmental successively characters GERMINATION embryo IMMATURE elongation LYASE lived translated 
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