AUCUBIN

作品数：7被引量：33H指数：3
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相关领域：医药卫生更多>>
相关作者：龙桢桢郑敬李静魏屹乔媛媛更多>>
相关机构：西南交通大学更多>>
相关期刊：《Animal Nutrition》《Medicinal Plant》《Science China(Life Sciences)》《Chinese Journal of Natural Medicines》更多>>
相关基金：国家自然科学基金上海市自然科学基金四川省科技支撑计划更多>>
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Aucubin mitigates the elevation of microglial aerobic glycolysis and inflammation in diabetic neuropathic pain via aldose reductase
《World Journal of Diabetes》2025年第5期346-362,共17页Xue-Zhen Zheng Hong-Yan Yu Ye-Ru Chen Jian-Sheng Fang 
Supported by National Natural Science Foundation of China,No.82001424.
BACKGROUND Treatment of diabetic neuropathy is often limited by side effects.Aucubin,an iridoid glycoside derived from natural plants,exhibits notable anti-inflammatory and antioxidant properties.AIM To investigate th...
关键词：Diabetic neuropathic pain AUCUBIN GLYCOLYSIS Aldose reductase MICROGLIA 
Anti-inflammatory effects of aucubin in cellular and animal models of rheumatoid arthritis被引量：6
《Chinese Journal of Natural Medicines》2022年第6期458-472,共15页ZHANG Yan TANG Li-Dong WANG Jian-Ying WANG Hao CHEN Xiao-Yun ZHANG Lei YUAN Ying 
This work was supported by the Natural Science Foundation of China(No.81773922);Shanghai Natural Science Foundation(No.19ZR1452000).
Rheumatoid arthritis(RA)is a chronic inflammatory autoimmune disease.It is known that aucubin(AU)exerts anti-inflammatory activity,but its effects and mechanisms in RA are unclear.This study investigated the anti-infl...
关键词：AUCUBIN Collagen-induced arthritis Synovial inflammation Bone erosion NF-/cB signaling pathway 
Potentials of using dietary plant secondary metabolites to mitigate nitrous oxide emissions from excreta of cattle:Impacts,mechanisms and perspectives被引量：3
《Animal Nutrition》2022年第2期327-334,共8页Jian Gao Guangyong Zhao 
National Natural Science Foundation of China(grant number 31772626).
Nitrous oxide(N_(2)O)is a potent greenhouse gas as well as the key component depleting the ozone sphere of the earth.Cattle have high feed and water intakes and excrete large amounts of urine and feces.N_(2)O can be p...
关键词：ANTHOCYANIN AUCUBIN CATTLE GLUCOSINOLATE Nitrous oxide TANNIN 
Study on the Pharmacological Effects of Aucubin
《Medicinal Plant》2022年第2期4-7,共4页Yue TENG Chenghao JIN 
Talent Training Program by the Central Government for the Reform and Development of Local Universities(2020GSP16);Innovation and Entrepreneurship Project for College Students(202110223003).
In this paper,the pharmacological effects of aucubin include anti-inflammatory effect,anti-tumor effect,neuroprotective effect,anti-cardiovascular disease effect,hepatoprotective effect,anti-oxidation effect and anti-...
关键词：AUCUBIN Pharmacological effects ANTI-INFLAMMATION ANTI-TUMOR NEUROPROTECTION 
S-8大孔吸附树脂分离纯化洒金桃叶珊瑚中桃叶珊瑚苷的工艺研究被引量：1
《安徽农业科学》2012年第28期13787-13789,共3页龙桢桢 乔媛媛 李静 郑敬 魏屹 成晓梅 
四川省科技支撑项目(2008SZ0009);中央高校基本科研专项(NO:SWJTU11ZT25)
[目的]研究大孔吸附树脂分离纯化桃叶珊瑚苷的工艺,为进一步精制洒金桃叶珊瑚中桃叶珊瑚苷奠定基础。[方法]以桃叶珊瑚苷为指标成分,用HPLC法测定桃叶珊瑚苷的含量,并优选大孔吸附树脂分离纯化桃叶珊瑚苷的最优工艺。[结果]S-8大孔吸附...
关键词：大孔吸附树脂 桃叶珊瑚苷(aucubin) 纯化 
Neuroprotection of aucubin in primary diabetic encephalopathy被引量：22
《Science China(Life Sciences)》2008年第6期495-502,共8页XUE HongYu1, JIN LiJi1,2, JIN Lei1, ZHANG Peng1, LI DanQing4, XIA YanQiu1, LU YaNan1 & XU YongPing1,3 1 Department of Bioscience and Biotechnology, Dalian University of Technology, Dalian 116024, China 2 State Key Laboratory of Fine Chemicals, Dalian University of Technology, Dalian 116024, China 3 Dalian SEM Bioengineer and Biotech Ltd., Dalian 116024, China 4 The Second Affiliated Hospital, Dalian Medical University, Dalian 116024, China 
the National Natural Science Foundation of China (Grant No. 30371053);the National Outstanding Youth Foundation of China (Grant No. 30125034);the Scientific and Technological Plan Project of Dalian City (Grant No. 2003B3NS024)
Hippocampal neuronal apoptosis accompanied by impairment of cognitive function occurs in primary diabetic encephalopathy. In this study, we investigated the neuroprotective mechanism of the iridoid glycoside, aucubin,...
关键词：AUCUBIN DIABETIC ENCEPHALOPATHY NEUROPROTECTION APOPTOSIS HIPPOCAMPUS 
A New Iridoid Glucoside from Lagotis yunnanensis被引量：2
《Chinese Chemical Letters》2003年第9期936-938,共3页XiaoDongYANG ShuangXiMEI JingFengZHAO GanPengLI HongBinZHANG LiangLI 
Phytochemical investigation of Lagotis yunnanensis led to the isolation and identification of a new iridoid glucoside 1, named as 10-O-(3,4-dimethoxy-(E)-cinnamoyl)aucubin. Its structure was elucidated by spectroscopi...
关键词：Lagotis yunnanensis iridoid glucoside 10-O-(3 4-dimethoxy-(E)-cinnamoyl)aucubin. 
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