supported by the National Key R&D Program of China[Grant number 2021YFC2100700];the National Natural Science Foundation of China[Grant numbers 22178372,32300069];TIB-VIB Joint Center of Synthetic Biology[Grant number TSBICIP-IJCP-002];the National Science Fund for Distinguished Young Scholars[Grant number 22325807];the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project[Grant numbers TSBICIP-KJGG-011,TSBICIP-CXRC-055];the Yellow River Delta Industry Leading Talents[Grant number DYRC20190212].
Genetically encoded circuits have been successfully utilized to assess and characterize target variants with desirable traits from large mutant libraries.Adenosylcobalamin is an essential coenzyme that is required in ...
supported by grants from the National Natural Science Foundation of China(Grant no.32260233 to Morigen);the Science and Technology Foundation of Inner Mongolia(Inner Mongolia Key Laboratory for Molecular Regulation of the Cell,Grant no.2021PT0002).
Transcription attenuation in response to the availability of a specific amino acid is believed to be controlled by alternative configurations of RNA secondary structures that lead to the arrest of translation or the r...
This work was supported by the Global Research Laboratory Program(NRF 2016K1A1A2912829)through the National Research Foundation of Korea(NRF);This work was also supported by the National Natural Science Foundation of China(grant number 21636001);Research Program of Beijing Municipal Education Commission(grant number KM201911417012);This work was also financially supported by the Office of the Ministry of Higher Education,Science,Research and Innovation;the Thailand Science Research and Innovation through the Kasetsart University Reinventing University Program 2021 and Department of Zoology,Faculty of Science,Kasetsart University;P.P.would like to acknowledge the supports provided by the International Affairs under the scholarship program of ASEAN+6 and Interdisciplinary Graduate Program in Bioscience in Kasetsart University.
A parallel screening of 27 different flavonoids and chalcones was conducted using 6 artificial naringenin-activated riboswitches(M1,M2,M3,O,L and H).A quantitative structure-property relationship approach was applied ...
Project supported by the Science Fund from the Key Laboratory of Hubei Province, China (Grant No. 201932003);the National Natural Science Foundation of China (Grant Nos. 1157324 and 31600592).
RNAs carry out diverse biological functions, partly because different conformations of the same RNA sequence can play different roles in cellular activities. To fully understand the biological functions of RNAs requir...
Supported by the National Natural Science Foundation of China(31600592);Hubei Key Laboratory of Economic Forest Germplasm Improvement and Resources Comprehensive Utilization,Hubei Collaborative Innovation Center for the Characteristic Resources Exploitation of Dabie Mountains(2017BX08)
Most riboswitches are characterized by two components, an aptamer domain that folds into a unique ligand binding pocket to interact with the ligand, and an expression platform that converts folding changes in the apta...
Overproduction of small-molecule chemicals using engineered microbial cells has greatly reduced the production cost and promoted environmental protection. Notably, the rapid and sensitive evaluation of the in vivo con...
supported by National Basic Research Program of China(973 Program)(Grant Nos.2013CB3296-01,2013CB329602);National Natural Science Foundation of China(Grant Nos.61127005,60910002,61379059,61472333,61402382,30970960);"Top University,Top Discipline"Funds for Minzu University of China(Grant No.10301-0150200518)
Currently, there are a lot of man-made biomolecular computing systems. However, it is rare to see man-made biomolecular intelligence system. Learning ability is one of the basic abilities of intelligence. Many organis...
T box sequences have been identified upstream of a large number of uncharacterized genes such as transporters in bacterial genomes. Expression of each T box family gene is induced by limitation for a specific amino ac...