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作品数:53被引量:104H指数:6
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相关领域:医药卫生农业科学更多>>
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相关机构:北京大学香港大学中国农业大学南开大学更多>>
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A novel model of central precocious puberty disease:Paternal MKRN3 gene-modified rabbit
《Animal Models and Experimental Medicine》2025年第3期511-522,共12页Bangzhu Chen Xing Ye Lihao Chen Tianping Liu Guiling Li Chula Sa Juan Li Ke Liu Weiwang Gu Gang Wang 
National Natural Science Foundation of China,Grant/Award Number:82101937;Guangdong Medical Science and Technology Research Fund Project,China,Grant/Award Number:B2024069;Guangzhou Science and Technology Plan Project,China,Grant/Award Number:2024A04J4923 and SL2023A04J02229。
Background:Makorin ring finger protein 3 gene(MKRN3)gene mutation is the most common genetic cause of central precocious puberty(CPP)in children.Due to the lack of ideal MKRN3-modified animal model(MKRN3-modified mice...
关键词:central precocious puberty gonadotropin inhibiting hormone(GnIH) gonadotropin releasing hormone(GnRH) MKRN3 RABBIT 
The Poor Performance of Neu5Gc for Endometrial Receptivity in Embryo Transfer
《Journal of Bio-X Research》2024年第3期93-96,共4页Yunfeng Lin Qicai Liu 
supported by the National Natural Science Foundation of Fujian(nos.2023J011312,2023Y9052,and 2021J02036);Wu Jieping Medical Foundation Research Special Project(320.6750.2021-19-4).
Neu5Gc is a common sialic acid in mammals,but humans cannot synthesize it independently.When Neu5Gc in the diet enters the body,the body produces antibodies against Neu5Gc,which in turn promotes the immune response an...
关键词:embryo transfer paternal gene products chronic inflammation hapten relative neu gc sialic acid immune response 
Evaluation of microRNA expression profiles in human sperm frozen using permeable cryoprotectant-free droplet vitrification and conventional methods
《Asian Journal of Andrology》2024年第4期366-376,共11页Li-Xin Zhang Jing Mao Yan-Dong Zhou Guang-Yao Mao Run-Fa Guo Hong-Shan Ge Xia Chen 
For sperm cryopreservation,the conventional method,which requires glycerol,has been used for a long time.In addition,the permeable cryoprotectant-free vitrification method has been continuously studied.Although the di...
关键词:CRYOPRESERVATION cryoprotectant-free vitrification early embryonic development paternal epigenetic inheritance sperm miRNAs SUCROSE 
Interaction between ozone and paternal smoking on fetal congenital heart defects among pregnant women at high risk a multicenter maternal-fetal medicine study被引量:1
《World Journal of Pediatrics》2024年第6期621-632,共12页Huan Wang Yan-Ping Ruan Sheng Ma Ya-Qi Wang Xiao-Yu Wan Yi-Hua He Jing Li Zhi-Yong Zou 
supported by the National Natural Science Foundation of China(82073573 to ZZY,U21A20523 to HYH);the Beijing Key Laboratory of Maternal-Fetal Medicine in Fetal Heart Disease(BZ0308 to HYH);the National Key Research and Development Program of China(2022YFC3703502 to LJ).
Background Evidence remains limited on the association between maternal ozone(O,)exposure and congenital heart defects(CHDs)in offspring,and few studies have investigated the interaction and modification of paternal s...
关键词:Congenital heart defects Fetal heart development Ozone exposure Tobacco smoking 
The Division of Labor in Parenting and Its Impact on Adolescent Development
《Social Sciences in China》2023年第4期175-198,共24页Zhu Xiaowen Wang Kaili Guo Zhirong Huang Deyuan 
The Law of the People's Republic of China on Family Education Promotion explicitly requires both parents to engage in their children's education, but so far there has not been sufficient empirical research on the divi...
关键词:family education division of labor in parenting FATHERING paternal participation adolescent development 
Paternally imprinted LATE-FLOWERING2 transcription factor contributes to paternal-excess interploidy hybridization barriers in wheat∞
《Journal of Integrative Plant Biology》2023年第12期2587-2603,共17页Guanghui Yang Man Feng Kuohai Yu Guangxian Cui Yan Zhou Lv Sun Lulu Gao Yumei Zhang Huiru Peng Yingyin Yao Zhaorong Hu Vincenzo Rossi Ive De Smet Zhongfu Ni Qixin Sun Mingming Xin 
This work was supported by the National Natural Science of China(31471479);the Chinese Universities Scientific Fund(2017TC035).
Interploidy hybridization between hexaploid and tetraploid genotypes occurred repeatedly during genomic introgression events throughout wheat evolution,and is commonly employed in wheat breeding programs.Hexaploid whe...
关键词:IMPRINTING interploidy cross WHEAT 
What are the contributions of maternal and paternal traits to fecundity and offspring development?A case study in an amphibian species,the spined toad Bufo spinosus
《Current Zoology》2023年第5期527-534,共8页Matthias Renoirt Frédéric Angelier Marion Cheron François Brischoux 
Funding was provided by the CNRS,the Agence de lʹEau Loire-Bretagne,the Agence de lʹEau Adour-Garonne,the Conseil Départemental des Deux-Sèvres,the Région Nouvelle-Aquitaine(Multistress 2017-1R20110,Aquastress 2018-1R20214,Amphitox 2019-1R20216);the ANSES(BiodiTox project 2019/1/031);the Plan dʹAction National ECOPHYTO(OFB-21-0941),and the CPER Econat.
Assessing the determinants of reproductive success is critical but often complicated because of complex interactions between parental traits and environmental conditions occurring during several stages of a reproducti...
关键词:clutch quality embryonic development larval development phenotype reproductive success 
A paternal protein facilitates sperm RNA delivery to regulate zygotic development
《Science China(Life Sciences)》2023年第10期2342-2353,共12页Dongdong Li Shijing Huang Yongping Chai Ruiqian Zhao Jing Gong Qiangfeng Cliff Zhang Guangshuo Ou Wenyu Wen 
the Ministry of Science and Technology of China(2019YFA0508401);the National Natural Science Foundation of China(31871394,82121004,32100538);Shanghai Municipal Science and Technology Major Project(2018SHZDZX01);the China Postdoctoral Science Foundation(2022M711844);the Young Elite Scientists Sponsorship Program by CAST(YESS20220102);ZJ Lab and Shanghai Center for Brain Science and Brain-Inspired Technology。
Sperm contributes essential paternal factors,including the paternal genome,centrosome,and oocyte-activation signals,to sexual reproduction.However,it remains unresolved how sperm contributes its RNA molecules to regul...
关键词:SPE-11 phase separation paternal factor early embryonic development 
Developmental origins of health and disease: Impact of paternal nutrition and lifestyle被引量:1
《Pediatric Investigation》2023年第2期111-131,共21页Qiaoyu Shi Kemin Qi 
The Research Funds of Reform and Development Budget from Beijing Municipal Science and Technology Commission,Grant/Award Number:bjsekyjs to K.Q.
Most epidemiological and experimental studies have focused on maternal influences on offspring’s health.The impact of maternal undernutrition,overnutrition,hypoxia,and stress is linked to adverse offspring outcomes a...
关键词:EPIGENETICS Mental health Metabolic outcomes OFFSPRING Paternal exposure Telomere length 
Paternal transgenerational nutritional epigenetic effect:A new insight into nutritional manipulation to reduce the use of antibiotics in animal feeding
《Animal Nutrition》2022年第4期142-151,共10页Xinyi Li Mengya Wang Shimin Liu Xiaodong Chen Yu Qiao Xiaojun Yang Junhu Yao Shengru Wu 
National Natural Science Foundation of China(31902184);Shaanxi Provincial Science and Technology Association Young Talents Lifting Program Project(20220203)。
The use of antibiotics in animal feeding has been banned in many countries because of increasing concerns about the development of bacterial resistance to antibiotics and potential issues on food safety.Searching for ...
关键词:Growth NUTRITION Immune Transgenerational epigenetic Antibiotic replacement 
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