AMIDASE

作品数：7被引量：25H指数：1
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相关领域：生物学更多>>
相关机构：安徽理工大学更多>>
相关期刊：《Science Bulletin》《Chinese Journal of Chemistry》《中国生物学文摘》《Chinese Chemical Letters》更多>>
相关基金：国家自然科学基金更多>>
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Acrylamide drives amidase-mediated gut dysbiosis to aggravate colitis
《Science Bulletin》2025年第2期157-161,共5页Daotong Li Yinghua Luo Huimin Fan Li Dong Xiaoying Zhang Yu Feng Meiling Tian Shuqing Zhang Wenjing Chen Lujia Zhang Jianwei Gao Xiangning Ma Xiaofei Wang Chen Ma Ruimao Zheng Xiaosong Hu Jinfeng Wang Fang Chen 
supported by the National Natural Science Foundation of China(32230081,32371511,and 32001677)。
Inflammatory bowel diseases(IBDs)are chronic intestinal inflammatory disorders that have emerged as a global public health challenge[1].Increased availability and consumption of processed foods is considered as a cruc...
关键词：diseases prevalence clarified 
Nitrogen slow-release behavior of oxamide granules in two different types of paddy soils被引量：1
《Pedosphere》2022年第6期856-865,共10页Xun LI Jinlong DONG Jingjing DUAN Wenzhong SHEN Zengqiang DUAN 
the National Key Research and Development Program of China(No.2017YFD0800103);the Strategic Priority Research Program of Chinese Academy of Sciences(No.XDA23020401)。
Oxamide is a potential slow-release nitrogen(N)fertilizer,especially under waterlogged conditions,due to its low solubility in water and the slow-release of ammonium by soil amidases.To investigate the effects of oxam...
关键词：amidase activity grain yield nitrogen use efficiency organic matter content pH slow-release fertilizer 
Enzymatic clickable functionalization of peptides via computationally engineered peptide amidase被引量：1
《Chinese Chemical Letters》2018年第7期1116-1118,共3页Tong Zhu Lu Song Ruifeng Li Bian Wu 
supported by the National Natural Science Foundation of China(No.31601412);the 100 Talent Program grant and Biological Resources Service Network Initiative(No.ZSYS-012);grant from the Chinese Academy of Sciences(No.SKT1604)
Directed peptides C-terminal modification enabled by the engineered biomolecular catalyst-peptide amidase 12 B has been achieved via computational protein engineering. The engineered enzyme exhibits great promising po...
关键词：Peptide amidase Opioid peptides C-terminal modification Click reaction FUNCTIONALIZATION 
Isoniazid metabolism and hepatotoxicity被引量：23
《Acta Pharmaceutica Sinica B》2016年第5期384-392,共9页Pengcheng Wang Komal Pradhan Xiao-bo Zhong Xiaochao Ma 
supported in part by the U.S. National Institute of Diabetes and Digestive and Kidney Diseases (DK090305) for Xiaochao Ma;the National Institute of General Medical Sciences (GM087376 and GM118367) for Xiao-bo Zhong
Isoniazid(INH) is highly effective for the management of tuberculosis.However,it can cause liver injury and even liver failure.INH metabolism has been thought to be associated with INH-induced liver injury.This review...
关键词：ISONIAZID METABOLISM HEPATOTOXICITY ANTI-TUBERCULOSIS N-ACETYLTRANSFERASE 2 AMIDASE 
Cloning, sequence analysis and expression of the gene encoding a novel wide-spectrum amidase belonging to the amidase signature superfamily from Achromobacter xylosoxidans
《中国生物学文摘》2007年第1期14-14,共1页Cai, G. Zhu, S. C. Wang, X. J. Jiang, W. H. 
关键词：无性繁殖 基因 遗传性 排列秩序 
Biocatalytic Synthesis of Highly Enantiopure 1,4-Benzodioxane-2-carboxylic Acid and Amide
《Chinese Journal of Chemistry》2006年第11期1665-1668,共4页刘军 王德先 郑企雨 王梅祥 
Project supported by the Major State Basic Research Development Program （No. 2003CB716005）, the Ministry of Science and Technology, the National Science Foundation of China, and the Chinese Academy of Sciences.
Catalyzed by Rhodococcus erythropolis AJ270, a nitrile hydratase and amidase containing microbial whole-cell catalyst, at 10 ℃ and with the use of methanol as a co-solvent, nitrile and amide biotransformations produc...
关键词：1 4-benzodioxane-2-carboxylic acid 1 4-benzodioxane-2-carboxamide biotransformation nitrile hydratase AMIDASE enantioselectivity 
Synthesis of Optically Active β-Alkyl-α-methylene-γ-butyro- lactones from Enantioselective Biotransformation of Nitriles, an Unusual Inversion of Enantioselectivity
《Chinese Journal of Chemistry》2002年第11期1291-1299,1129,共10页赵生敏 王梅祥 
theMajorStateBasicResearchDevelopmentProgram (No.2 0 0 0 0 775 0 6 ) ,andtheNationalNaturalScienceFoundationofChina (No .2 0 0 0 32 0 2 0 )andChineseAcademyofSciences
A new approach to optically active β-alkyl-α-methylene-γ-butyrolactone derivatives was reported from the Rhodococcus sp. AJ270-catalyzed hydrolysis of appropriate nitriles. The inversion of enantioselectivity of th...
关键词：BIOTRANSFORMATION nitrile hydratase AMIDASE optically active β-alkyl-α-methylene-γ-butyrolactone inversion of enantioselectivity 
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