supported by the National Program on the Key Research Project of China(2022YFC2604201);the European Union’s Horizon 2020 Research and Innovation Programme(861917–SAFFI);the Zhejiang Provincial Natural Science Foundation of China(LR19C180001);the Hainan Provincial Joint Project of Sanya Yazhou Bay Science and Technology City(2021JJLH0083);the Zhejiang Provincial Key R&D Program of China(2023C03045,2022C02024 and 2021C02008);the Open Project Program of the Jiangsu Key Laboratory of Zoonosis(R1902)。
Understanding changes in pathogen behavior(e.g.increased virulence,a shift in transmission channel)is critical for the public health management of emerging infectious diseases.Genome degradation via gene depletion or ...
Supported by the National Natural Science Foundation of China(No.81374039)
Objective: To study the preventive effect of herbal formulation on experimental murine urinary tract infection (UTI) induced by Dr Escherichia coil 11128. Methods: E. coil 11128 carrying Dr fimbriae was isolated f...
Enteric disorders in pigs are related to the fimbriae F4 (K88), F5 (K99), F6 (987P), F41 and F18 of enterotoxigenic Escherichia coli (ETEC). Immunization of sows with adhesins is important to stimulate the production ...
Microbial infections are typically initiated by the colonization of tissues by a specific mechanism that promotes adherence to host cells or tissues. In this work, we characterized the ability of Gallibacterium anatis...
Uropathogenic Escherichia coli(UPEC)is the leading cause of urinary tract infections in women,causing significant morbidity and mortality in this population.Adherence to host epithelial cells is a pivotal step in the ...
Objective:In the present study we try to correlate between pathogenic intrinsic factor of Escherichia coli(E.coli) presented with different fimbria genotyes and biofilm formation with host immune factor entitled inter...
MM-3 was a live vaccine strain candidate for protecting neonatal piglets from diarrhea. Designed in the 1980s, a high degree of protection from colibacillosis was afforded to piglets in a challenge study and field tri...
Project supported by the National Natural Science Foundation of China (Grant No. 39570408)
CS3 fimbriae, which are the strong immunogen, are produced by human enterotoxigenic Escherichia coli (ETEC). The possibility of using CS3 as a carrier of foreign antigenic determinants was investigated. A SacⅡ site s...
The author has observed the epithelium and basement membrane of uterus, oviduct and fimbriae in mice under the TEM by oral administration of AgNo3 tracer. The results showed that there was obvious deposit o...