云南高校图书馆联盟文献共享服务平台- CHIMERIC

CHIMERIC: 作品数：147被引量：459H指数：12; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：宋小凯陈晓亚于晓红许智宏沈新莲更多>>; 相关机构：南京农业大学江苏省农业科学院中国科学院上海生命科学研究院中国科学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划上海市自然科学基金更多>>

Landscape of chimeric RNAs in COVID-19 patient blood: 《Genes & Diseases》2025年第3期599-610,共12页Samuel Haddox Ping Wu Sandeep Singh Fujun Qin Jack Engel Andrea Kian Syed Ahmad Hui Li Peng Wu; supported by the National Institutes of Health(USA)(No.R01GM132138 to H.L.).; Despite the availability of efficacious vaccines, COVID-19 persists and our knowledge of how SARS-CoV-2 infection affects host transcriptomics remains incomplete. Transcriptome analysis, which has progressed our under...; 关键词：BLOOD Chimeric RNA COVID-19 PTBP1 SARS-CoV-2

Chimeric RNA landscape in the placenta: A transcriptomic analysis revealing novel diagnostic biomarkers forpreeclampsia: 《Genes & Diseases》2025年第1期80-84,共5页Jingjing Xu Xinrui Shi Shitong Lin Sandeep Singh Samuel Haddox Christopher Phung Tommy Manley Ningxi Huang Peng Wu Hui Li; fund from the Chinese Study Council for the studying abroad program.; Chimeric RNAs,hybrid transcripts containing exons from two originally separate genes,have been extensively studied in various cancer types and non-cancerous tissues.1,2 The hybrid transcripts can arise through differe...; 关键词：LANDSCAPE CHROMOSOMAL REVEALING

Chitosan capped-NLCs enhanced codelivery of gefitinib and simvastatin into MDR HCC:impact of compositions on cell death,JNK3,and Telomerase: 《Oncology Research》2025年第2期477-492,共16页GAMALELDIN I.HARISA RIYAD F.ALZHRANI ABDULRAHMAN A.ALLUHAIDAN SULTAN M.ALAMRI AHMED H.BAKHEIT HANADI H.ASIRI SABRY M.ATTIA; Support Project(RSPD2024R1037),King Saud University,Riyadh,Saudi Arabia.; Background:Hepatocellular carcinoma(HCC)is a health problem due to multi-drug resistance(MDR).Codelivery of multiple oncotherapy in one cargo as chimeric cancer therapy(CCT)is suggested as a solution for MDR.This stud...; 关键词：Codelivery Chimeric therapy Hepatocellular carcinoma Multi-drug resistance TELOMERASE

An assessment model for efficacy of autologous CD19 chimeric antigen receptor T-cell therapy and relapse or refractory diffuse large B-cell lymphoma risk: 《Chinese Medical Journal》2025年第1期108-110,共3页Bin Xue Yifan Liu Min Zhang Gangfeng Xiao Xiu Luo Lili Zhou Shiguang Ye Yan Lu Wenbin Qian Li Wang Ping Li Aibin Liang; supported by grants from the National Key R&D Program of China(No.2021YFA1100800);National Natural Science Foundation of China(Nos.81830004 and 82070168);Translational Research Grant of NCRCH(No.2020ZKZC04);Shanghai Municipal Health Commission(No.2020CXJQ02);Cultivation project of National Natural Science Foundation of Shanghai Tongji Hospital(No.GJPY2332).; To the Editor:Autologous CD19 chimeric antigen receptor(CAR)T-cell therapy has emerged as a crucial treatment option for patients with relapsed or refractory diffuse large B-cell lymphoma(r/r DLBCL).[1]While CAR-T-cel...; 关键词：therapeutic efficacy chimeric antigen REFRACTORY predictive model Chimeric Antigen Receptor T cell therapy diffuse large B cell lymphoma

Development of a novel HER2-CAR monocyte cell therapy with controllable proliferation and enhanced anti-tumor efficacy被引量：1: 《Chinese Medical Journal》2024年第21期2590-2602,共13页Bing Yang Xiaoxue Wang Xundong Wei Jie Ma; supported by the National High-Level Hospital Clinical Research Funding(No.BJ-2022-118);CAMS Innovation Fund for Medical Sciences(No.2021-1-I2M-050);National Natural Science Foundation of China(Nos.52273281 and 82173109);Guangxi Science and Technology Base and Talent Special Projects(No.AD21220001).; Background:One of the significant challenges for cell therapies,such as chimeric antigen receptor(CAR)-T cell therapy,is the poor infiltration of immune cells into tumor tissues.CAR-monocytes/macrophages(CAR-M)are pro...; 关键词：Receptors chimeric antigen Macrophages MONOCYTES Cell suicide Antibody-dependent cell phagocytosis METALLOPROTEINASES

Advancing cell-based therapy in sepsis:An anesthesia outlook: 《Chinese Medical Journal》2024年第13期1522-1534,共13页Hui Ye Xiaoyu Zou Xiangming Fang; National Natural Science Foundation of China(No.82230074); Sepsis poses a health challenge globally owing to markedly high rates of morbidity and mortality.Despite employing bundle therapy over two decades,approaches including transient organ supportive therapy and clinical t...; 关键词：SEPSIS PERIOPERATIVE Receptors chimeric antigen Immunotherapy adoptive Perfusion Tissue repair Multiple organ failure Shock septic

Chimeric Monkey Born Alive with a High Contribution of Donor Cells: 《Neuroscience Bulletin》2024年第6期849-851,共3页Jia Huang Jun Wu; supported by the National Institutes of Health(UM1HG011996,R01HD103627,and R01GM138565);NYSCF,ARSM,and The Welch Foundation(I-2088).; Chimeras,which consist of cells from different individuals or different species,represent an important tool in biological research.Beginning in the early twentieth century,studies on chimeras have been focusing on und...; 关键词：mechanisms advances DEVELOPMENTAL

Aptasensing biosynthesized phosphatidylserine with a AuNPs nanozyme-based colorimetric aptasensor: 《Food Science and Human Wellness》2024年第2期823-829,共7页Sai Wang Rui Ma Chengqiang Li Ling Zhang Haiyang Zhang Xuehan Li Xiangzhao Mao; supported by the National Natural Science Foundation of China(31922072);the Natural Science Foundation of Shandong Province(ZR2020JQ15);the Taishan Scholar Project of Shandong Province(tsqn201812020)。; Sensitive monitoring of the target products during the biosynthesis process is crucial,and facile analytical approaches are urgently needed.Herein,phosphatidylserine(PS)was chosen as the model target,a colorimetric ap...; 关键词：PHOSPHATIDYLSERINE Chimeric aptamer AuNPs nanozyme Colorimetric aptasensor

Humanizing pig kidneys via chimeric complementation: 《Cell Research》2024年第3期189-190,共2页Jia Huang Jun Wu; An ultimate goal in stem cell research is to use induced pluripotent stem cells(iPSCs)to generate transplantable human organs in large livestock.In a groundbreaking study by Wang et al.,the researchers showcased that ...; 关键词：ORGANS FETUS breaking

Long-term in vivo chimeric cells tracking in non-human primate: 《Protein & Cell》2024年第3期207-222,共16页Junmo Wu Yu Kang Xiang Luo Shaoxing Dai Yuxi Shi Zhuoyao Li Zengli Tang Zhenzhen Chen Ran Zhu Pengpeng Yang Zifan Li Hong Wang Xinglong Chen Ziyi Zhao Weizhi ji Yuyu Niu; supported by grants from the National Key R&D Program of China(2021YFA0805700 and 2021YFA1102000);the National Natural Science Foundation of China(U2102204);the Natural Science Foundation of Yunnan Province(202001BC070001 and 202102AA100053).; Non-human primates(NHPs)are increasingly used in preclinical trials to test the safety and efficacy of biotech-nology therapies.Nonetheless,given the ethical issues and costs associated with this model,it would be hig...; 关键词：pluripotent stem cells bioluminescence imaging non-human primates

CHIMERIC