云南高校图书馆联盟文献共享服务平台- CHIMERIC

CHIMERIC: 作品数：144被引量：457H指数：12; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：宋小凯陈晓亚于晓红许智宏沈新莲更多>>; 相关机构：南京农业大学江苏省农业科学院中国科学院上海生命科学研究院中国科学院更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划上海市自然科学基金更多>>

Chimeric RNA landscape in the placenta: A transcriptomic analysis revealing novel diagnostic biomarkers forpreeclampsia: 《Genes & Diseases》2025年第1期80-84,共5页Jingjing Xu Xinrui Shi Shitong Lin Sandeep Singh Samuel Haddox Christopher Phung Tommy Manley Ningxi Huang Peng Wu Hui Li; fund from the Chinese Study Council for the studying abroad program.; Chimeric RNAs,hybrid transcripts containing exons from two originally separate genes,have been extensively studied in various cancer types and non-cancerous tissues.1,2 The hybrid transcripts can arise through differe...; 关键词：LANDSCAPE CHROMOSOMAL REVEALING

Development of a novel HER2-CAR monocyte cell therapy with controllable proliferation and enhanced anti-tumor efficacy被引量：1: 《Chinese Medical Journal》2024年第21期2590-2602,共13页Bing Yang Xiaoxue Wang Xundong Wei Jie Ma; supported by the National High-Level Hospital Clinical Research Funding(No.BJ-2022-118);CAMS Innovation Fund for Medical Sciences(No.2021-1-I2M-050);National Natural Science Foundation of China(Nos.52273281 and 82173109);Guangxi Science and Technology Base and Talent Special Projects(No.AD21220001).; Background:One of the significant challenges for cell therapies,such as chimeric antigen receptor(CAR)-T cell therapy,is the poor infiltration of immune cells into tumor tissues.CAR-monocytes/macrophages(CAR-M)are pro...; 关键词：Receptors chimeric antigen Macrophages MONOCYTES Cell suicide Antibody-dependent cell phagocytosis METALLOPROTEINASES

Advancing cell-based therapy in sepsis:An anesthesia outlook: 《Chinese Medical Journal》2024年第13期1522-1534,共13页Hui Ye Xiaoyu Zou Xiangming Fang; National Natural Science Foundation of China(No.82230074); Sepsis poses a health challenge globally owing to markedly high rates of morbidity and mortality.Despite employing bundle therapy over two decades,approaches including transient organ supportive therapy and clinical t...; 关键词：SEPSIS PERIOPERATIVE Receptors chimeric antigen Immunotherapy adoptive Perfusion Tissue repair Multiple organ failure Shock septic

Chimeric Monkey Born Alive with a High Contribution of Donor Cells: 《Neuroscience Bulletin》2024年第6期849-851,共3页Jia Huang Jun Wu; supported by the National Institutes of Health(UM1HG011996,R01HD103627,and R01GM138565);NYSCF,ARSM,and The Welch Foundation(I-2088).; Chimeras,which consist of cells from different individuals or different species,represent an important tool in biological research.Beginning in the early twentieth century,studies on chimeras have been focusing on und...; 关键词：mechanisms advances DEVELOPMENTAL

Aptasensing biosynthesized phosphatidylserine with a AuNPs nanozyme-based colorimetric aptasensor: 《Food Science and Human Wellness》2024年第2期823-829,共7页Sai Wang Rui Ma Chengqiang Li Ling Zhang Haiyang Zhang Xuehan Li Xiangzhao Mao; supported by the National Natural Science Foundation of China(31922072);the Natural Science Foundation of Shandong Province(ZR2020JQ15);the Taishan Scholar Project of Shandong Province(tsqn201812020)。; Sensitive monitoring of the target products during the biosynthesis process is crucial,and facile analytical approaches are urgently needed.Herein,phosphatidylserine(PS)was chosen as the model target,a colorimetric ap...; 关键词：PHOSPHATIDYLSERINE Chimeric aptamer AuNPs nanozyme Colorimetric aptasensor

Humanizing pig kidneys via chimeric complementation: 《Cell Research》2024年第3期189-190,共2页Jia Huang Jun Wu; An ultimate goal in stem cell research is to use induced pluripotent stem cells(iPSCs)to generate transplantable human organs in large livestock.In a groundbreaking study by Wang et al.,the researchers showcased that ...; 关键词：ORGANS FETUS breaking

Long-term in vivo chimeric cells tracking in non-human primate: 《Protein & Cell》2024年第3期207-222,共16页Junmo Wu Yu Kang Xiang Luo Shaoxing Dai Yuxi Shi Zhuoyao Li Zengli Tang Zhenzhen Chen Ran Zhu Pengpeng Yang Zifan Li Hong Wang Xinglong Chen Ziyi Zhao Weizhi ji Yuyu Niu; supported by grants from the National Key R&D Program of China(2021YFA0805700 and 2021YFA1102000);the National Natural Science Foundation of China(U2102204);the Natural Science Foundation of Yunnan Province(202001BC070001 and 202102AA100053).; Non-human primates(NHPs)are increasingly used in preclinical trials to test the safety and efficacy of biotech-nology therapies.Nonetheless,given the ethical issues and costs associated with this model,it would be hig...; 关键词：pluripotent stem cells bioluminescence imaging non-human primates

Prevention of hepatitis B reactivation in patients with hematologic malignancies treated with novel systemic therapies:Who and Why?: 《World Journal of Gastroenterology》2024年第5期509-511,共3页Matteo Tonnini Clara Solera Horna Luca Ielasi; The risk of reactivation in patients with chronic or past/resolved hepatitis B virus(HBV)infection receiving chemotherapy or immunosuppressive drugs is a wellknown possibility.The indication of antiviral prophylaxis w...; 关键词：Hepatitis B reactivation Hepatitis B virus Antiviral prophylaxis Hematologic malignancies Chimeric antigens receptor-T cell therapy Immune checkpoint inhibitors

γδT cells:Major advances in basic and clinical research in tumor immunotherapy被引量：1: 《Chinese Medical Journal》2024年第1期21-33,共13页Yueqi Zhao Peng Dong Wei He Jianmin Zhang Hui Chen; supported by grants from the National Natural Science Foundation of China(Nos.32270915,31970843,82071791,U20A20374,and 81972886);National Key Research and Development Program of China(No.2022YFC3602004);CAMS Initiative for Innovative Medicine(Nos.2021-I2M-1-005,2021-I2M-1-035,and 2021-I2M-1-053);Haihe Laboratory of Cell Ecosystem Innovation Fund(No.22HHXBSS00028);CAMS Central Public Welfare Scientific Research Institute Basal Research Expenses(No.3332020035);Changzhou Science and Technology Support Plan(No.CE20215008);Beijing Municipal Commission of Science and Technology Fund for Innovative Drug(No.Z221100007922040); γδT cells are a kind of innate immune T cell.They have not attracted sufficient attention because they account for only a small proportion of all immune cells,and many basic factors related to these cells remain unc...; 关键词：Gamma-delta T-cells T cell receptor CD1A Tumor immunotherapy Receptors chimeric antigen Vδ1 cells αβT cells

抗SARS-CoV-2变异株的广谱mRNA疫苗RQ3013的临床前研究被引量：5: 《Science Bulletin》2023年第24期3192-3206,M0006,共16页谭舒丹赵京华胡雪李玉凤武子涵逯国亮于朝丽杜彬荷刘燕李丽陈煜琛李晔姚艳丰张小宇饶具红高歌彭云刘航袁志明刘佳王倩然胡恒睿高小博周辉俞航徐颖洁余巍冯琳王曼丽单超卢静林金钟; supported by Fudan University Special Funds for COVID-19;the National Natural Science Foundation of China(32130063);the National Key Research and Development Program of China(2021YFE0201900 and 2021YFC2301700);China Postdoctoral Science Foundation(2020T130017ZX);the Starry Night Science Fund at Shanghai Institute for Advanced Study of Zhejiang University(SN-ZJU-SIAS-009);the STS Regional Key Project(KFJSTS-QYZD-2021-12-001)from Chinese Academy of Sciences;Hubei Science and Technology Major Project(2021ACB0004)。; 全球SARS-CoV-2病毒的不同变异株导致已接种疫苗的人群中突破性感染的比例上升,迫切需要研发更为有效和广谱的COVID-19疫苗.本研究报告了一项mRNA疫苗RQ3013的临床前研究结果,旨在提供对SARS-CoV-2各种变异株(VOCs)的广谱保护.RQ3013疫...; 关键词：RQ3013 COVID-19 mRNA vaccine SARS-CoV-2 Chimeric spike

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