LIPOGENESIS

作品数：69被引量：233H指数：8
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High omega arachidonic acid/docosahexaenoic acid ratio induces mitochondrial dysfunction and altered lipid metabolism in human hepatoma cells被引量：2
《World Journal of Hepatology》2020年第3期84-98,共15页Reem Ghazali Kosha J Mehta SW Annie Bligh Ihab Tewfik Dahn Clemens Vinood B Patel 
BACKGROUND Non-alcoholic fatty liver disease(NAFLD) is a common cause of liver disease worldwide and is a growing epidemic. A high ratio of omega-6 fatty acids to omega-3 fatty acids in the diet has been implicated in...
关键词：Non-alcoholic FATTY liver disease LIPOGENESIS OMEGA FATTY ACIDS Mitochondrial dysfunction Reactive oxygen species Oxidative stress 
Lipogenesis in Huh7 cells is promoted by increasing the fructose: Glucose molar ratio被引量：1
《World Journal of Hepatology》2016年第20期838-843,共6页Fernando Windemuller Jiliu Xu Simon S Rabinowitz M Mahmood Hussain Steven M Schwarz 
AIM: To determine whether hepatocyte lipogenesis, in an in vitro cell culture model, is modulated by adjusting culture media monosaccharide content and concentration.METHODS: Hepatocytes(Huh7), demonstrating glucose a...
关键词：HEPATOCYTES CHOLESTEROL TRIGLYCERIDES FRUCTOSE GLUCOSE 
Peroxisome proliferator-activated receptors as targets to treat non-alcoholic fatty liver disease被引量：21
《World Journal of Hepatology》2015年第8期1012-1019,共8页Vanessa Souza-Mello 
Lately, the world has faced tremendous progress in the understanding of non-alcoholic fatty liver disease(NAFLD) pathogenesis due to rising obesity rates. Peroxisome proliferator-activated receptors(PPARs) are transcr...
关键词：PEROXISOME proliferator-activated receptors Non-alcoholic FATTY liver disease Obesity Treatment Insulin resistance BETA-OXIDATION LIPOGENESIS 
Role of unfolded protein response in lipogenesis被引量：1
《World Journal of Hepatology》2010年第6期203-207,共5页Ze Zheng, Chunbin Zhang, Kezhong Zhang, Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI 48201, United States , Department of Immunology and Mic robiology, Wayne State University School of Medicine, Detroit, MI 48201, United States 
Supported partially by the American Heart Association (AHA) Scientist Development Award (0635423Z);the AHA Grant-in-Aid (09GRNT2280479);the Department of Defense Breast Cancer Research Program (BC095179P1);the Karmanos Cancer Institute Pilot Grant
The signal transduction network in regulating lipid metabolism is a hot topic of biomedical research. Recent research endeavors reveal that intracellular stress signaling from a cellular organelle called endoplasmic r...
关键词：Endoplasmic reticulum stress Unfolded protein response LIPOGENESIS HEPATIC LIPID METABOLISM METABOLIC DISEASE 
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