supported by the National Natural Science Foundation of China(52000132 and 51978201);Open Project of State Key Laboratory of Urban Water Resource and Environment,Harbin Institute of Technology(HC202241);the Fundamental Research Funds for the Central Universities.
This study demonstrates the feasibility and effectiveness of utilizing native soils as a resource for inocula to produce n-caproate through the chain elongation(CE)platform,offering new insights into anaerobic soil pr...
Carnitine Palmitoyl Transferase II (CPTII) is a very important enzyme that helps with the oxidation of long-chain fatty acid to produce energy. Deficiency in CPTII will lead to energy deficiency in the case of fasting...
This work was supported by award AI144967(to H.Z.)from the U.S.National Institutes of Health(NIH)and awards DE-SC0018260 and DESC0018420(to H.Z.)from the U.S.Department of Energy.
Overproduction of polyketides has been a challenge for metabolic engineering for decades.However,recent studies have demonstrated that in both native host and heterologous host,engineeringβ-oxidation pathways can lea...
Mitochondria and peroxisomes are small ubiquitous organelles. They both play major roles in cell metabolism,especially in terms of fatty acid metabolism,reactive oxygen species(ROS) production,and ROS scavenging,and i...
Lately, the world has faced tremendous progress in the understanding of non-alcoholic fatty liver disease(NAFLD) pathogenesis due to rising obesity rates. Peroxisome proliferator-activated receptors(PPARs) are transcr...
This work was supported by grants from the National Natural Science Foundation of China (No. 81241021) and Beijing Municipal Natural Science Foundation (No. 7132215).
Background Preeclampsia (PE) is associated with abnormal fatty acid beta-oxidation (FAO), especially metabolic disorders of long-chain fatty acid oxidation. The role of FAO dysfunction in inadequate invasion is un...
The role of free fatty acids (FFAs) as a source of energy and their functions in energy transport within the body are well established. Equally important is a role that FFAs play in oxidative stress following cell mem...