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ACETYL: 作品数：190被引量：325H指数：9; 导出分析报告; 相关领域：理学医药卫生更多>>; 相关作者：孙久荣宋新峰王淘淘王敏汪汉卿更多>>; 相关机构：中国科学院沈阳药科大学台湾大学华中科技大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金中国博士后科学基金国家重点基础研究发展计划北京市自然科学基金更多>>

Comparative proteomic analysis of plasma exosomes reveals the functional contribution of N-acetyl-alpha-glucosaminidase to Parkinson’s disease: 《Neural Regeneration Research》2025年第10期2998-3012,共15页Yuan Zhao Yidan Zhang Xin Liu Jian Zhang Ya Gao Shuyue Li Cui Chang Xiang Liu Guofeng Yang; supported by the Science and Technology(S&T)Program of Hebei Province,No.22377798D(to YZ).; Parkinson’s disease is the second most common progressive neurodegenerative disorder,and few reliable biomarkers are available to track disease progression.The proteins,DNA,mRNA,and lipids carried by exosomes reflect...; 关键词：biomarker diagnosis EXOSOMES N-acetyl-alpha-glucosaminidase Parkinson’s disease proteomic α-synuclein

Aging-induced memory loss due to decreased N1-acetyl-5-methoxykynuramine,a melatonin metabolite,in the hippocampus:a potential prophylactic agent for dementia被引量：1: 《Neural Regeneration Research》2025年第6期1705-1706,共2页Kazuki Watanabe Atsuhiko Hattori; supported by JSPS KAKENHI Grant Number JP22K11823 to AH and JP22J01508 to KW。; Melatonin(N-acetyl-5-methoxytryptamine)is known as the hormone of darkness because it is synthesized at night and involved in regulating the circadian clock.The hormone is primarily synthesized by the vertebrate pinea...; 关键词：metabolism primarily AGENT

Mucopolysaccharidosis typeⅢB:a current review and exploration of the AAV therapy landscape被引量：1: 《Neural Regeneration Research》2024年第2期355-359,共5页Courtney J.Rouse Victoria N.Jensen Coy D.Heldermon; supported by Sanfilippo Children’s Foundation;Sanfilippo Fundacja;Sanfilippo Initiative;Cure Sanfilippo;Lacerta Therapeutics;NIH/NINDS R01NS102624(to CDH)。; Mucopolysaccharidoses typeⅢB is a rare genetic disorder caused by mutations in the gene that encodes for N-acetyl-alpha-glucosaminidase.This results in the aggregation of heparan sulfate polysaccharides within cell l...; 关键词：adeno-associated virus central nervous system gene therapy heparan sulfate immune response mucopolysaccharidoses type IIIB N-acetyl-alpha-glucosaminidase newborn screening

N-acetyl-L-leucine: a promising treatment option for traumatic brain injury: 《Neural Regeneration Research》2022年第9期1957-1958,共2页Chinmoy Sarkar Marta M.Lipinski; supported by IntraBio and NIH funding(R01NS091218 and R01NS091218)to MML.; Traumatic brain injury(TBI)is a mechanical injury to the brain,which can be sustained due to falls,accidents,contact sports or in combat situation.It is a serious health problem-affecting people of all ages worldwide....; 关键词：SUSTAINED TRAUMATIC injury

N-acetyl proline-glycine-proline: implications for neurological disorders: 《Neural Regeneration Research》2016年第6期898-899,共2页Jeff W.Hill Edwin M.Nemoto; N-acetyl proline-glycine-proline（ac-PGP）is a matrix-derived chemoattractant,or matrikine,produced by the degradation of collagen.Ac-PGP was first identified in studies of alkali eye injury in rabbits（Pfister et al....; 关键词：proline glycine acetyl neurological neuronal collagen neutrophil alkali potent chemokine

Impairment of cognitive function and reduced hippocampal cholinergic activity in a rat model of chronic intermittent hypoxia被引量：1: 《Neural Regeneration Research》2011年第17期1301-1305,共5页Chunling Zhao Yan Chen Chunlai Zhang Linya Lā Qian Xu; a grant from Luzhou Medical College,No.2009; The present study established a rat model of chronic intermittent hypoxia （CIH） to simulate obstructive sleep apnea syndrome. CIH rats were evaluated for cognitive function using the Morris water maze, and neuronal ...; 关键词：hypoxia brain memory dysfunction choline acetyl transferase nicotinic acetylcholinereceptor chronic intermittent hypoxia RAT neural regeneration

Tolerance of nestin^+ cholinergic neurons in the basal forebrain against colchicine-induced cytotoxicity被引量：4: 《Neural Regeneration Research》2011年第24期1860-1864,共5页Jing Yu Kaihua Guo Dongpei Li Jinhai Duan Juntao Zou Junhua Yang Zhibin Yao; the National Natural Science Foundation of China,No. 30700436; In the present study we injected colchicine into the lateral ventricle of Sprague-Dawley rats to investigate the effects of colchicine on the number of different-type neurons in the basal forebrain and to search for n...; 关键词：COLCHICINE basal forebrain choline acetyl transferase nestin PARVALBUMIN

Effects of cotransplantated Schwann cells and neural stem cells in a rat model of Alzheimer's disease被引量：13: 《Neural Regeneration Research》2011年第4期245-251,共7页Yan Zhan Dihui Ma Yu Zhang; the Science and Technology Development Foundation of Jilin Province, No. 200505204, 200705129; Schwann cells （SCs） are significantly better at promoting neural stem cell （NSCs） proliferation, differentiation and synaptic formation when cocultured with NSCs in vitro, compared with cultured in a single nerve ...; 关键词：Schwann cells neural stem cells CO-TRANSPLANTATION ETHOLOGY glial fibrillary acidic protein S100Β choline acetyl transferase mRNA Alzheimer＇s disease

Protective effects of transplanted neural stem cells on the brain of Alzheimer’s disease rats被引量：9: 《Neural Regeneration Research》2010年第11期825-832,共8页Yan Zhan Dihui Ma Yu Zhang Ming Chang Linsen Hu; the Jilin Pro-vincial Technology Devel-opment Foundation, No. 200505204, 200705129;the Postdoctorate Founda-tion from Northeast Normal University, No. 111258000; BACKGROUND： To date, no drugs are able to halt the progression of Alzheimer＇s disease （AD）. Neural stem cells （NSCs） transplantation has been widely used to treat AD, but the mechanism of AD treatment remains un...; 关键词：neural stem cells Alzheimer＇s disease choline acetyl transferase glial fibrillary acidic protein S100Β proteomics

Effects of Naotan Pill on repair of neural cells and cognitive disorders in juvenile rats following hypoxia and ischemia: 《Neural Regeneration Research》2009年第6期455-461,共7页Yuxiang Wei Huiqing Zhang Shenglu Lu Bingrong Dang Jianping Hong Qingxiang Gao; the Nomarch Foundation Program of Gansu Province,No. Gs024-A43-015;the Foundation of General Charity Committee of Gansu Province; BACKGROUND： Hypoxia and ischemia induce neuronal damage, decreased neuronal numbers and synaptophysin levels, and deficits in learning and memory functions. Previous studies have shown that lycium barbarum polysaccha...; 关键词：Naotan Pill cognition SYNAPTOPHYSIN choline acetyl transferase ceil damage glutamate juvenile hypoxia-ischemia rats

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