云南高校图书馆联盟文献共享服务平台- DRUGS

检索规则说明：AND代表“并且”；OR代表“或者”；NOT代表“不包含”；(注意必须大写,运算符两边需空一格)

检索范例：范例一： (K=图书馆学 OR K=情报学) AND A=范并思　　　　范例二：J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual

全部期刊核心期刊 EI来源期刊 SCI来源期刊 CA来源期刊 CSCD来源期刊 CSSCI来源期刊

Targeting novel sites represents an effective strategy for combating drug resistance: 《Chinese Chemical Letters》2025年第1期3-5,共3页Shaoqing Du Xinyong Liu Xueping Hu Peng Zhan; Drug resistance poses an escalating global challenge in the battle against infections.The effectiveness of conventional antibiotics and other anti-infective drugs is waning as microbes develop heightened resistance to...; 关键词：resistance DRUGS HUMANITY

FDA approved fluorine-containing drugs in 2023: 《Chinese Chemical Letters》2024年第11期111-122,共12页Qian Wang Yeping Bian Gagan Dhawan Wei Zhang Alexander E.Sorochinsky Ata Makarem Vadim A.Soloshonok Jianlin Han; support from the National Natural Science Foundation of China (No.21761132021);the Qing-Lan Project of Jiangsu Province (for Han) and IKERBASQUE,Basque Foundation for Science (for Soloshonok)。; This review profiles twelve fluorine-containing drugs approved by the US Food and Drug Administration(FDA) for the clinic in 2023.These small molecule drugs represent such therapeutic areas as cancer,neuromuscular dis...; 关键词：Fluorine-containing compounds Blockbuster drugs Pharmaceuticals ANTI-CANCER Drug design and development Asymmetric synthesis

Photochemical reactions as synthetic tool for pharmaceutical industries被引量：1: 《Chinese Chemical Letters》2024年第9期9-31,共23页Shehla Khalid Muhammad Bilal Nasir Rasool Muhammad Imran; In the quest for new agrochemicals and pharmaceuticals,chemists seek access to reliable and mild synthetic techniques to allow for the systematic modification of chemical structures,exploration of unexplored chemical ...; 关键词：PHOTOCATALYST Photochemical reactions DRUGS Natural products Late-stage functionalization

Photocatalytic synthesis of small-molecule drugs by porous framework materials被引量：2: 《Chinese Chemical Letters》2024年第3期52-65,共14页Yingying Zhao Jiangpei Yuan Lei Zhu Yu Fang; financially supported by the National Natural Science Foundation of China(NSFC,Nos.21501133,22371067);the China Hunan Provincial Science&Technology Department(Nos.2020RC3020 and 2021JJ20021)。; Small-molecule drugs are widely used in daily life.There are still issues with the current industrial synthesis techniques for small-molecule drugs,such as the use of expensive metal catalysts,convoluted reaction proc...; 关键词：Small-molecule drug Porous framework materials PHOTOCATALYSIS

The 3^(rd) Xihua Chemistry and Biomedicine Forum: 《Chinese Chemical Letters》2024年第2期1-2,共2页Yahui Zhang Zhouyu Wang Leyong Wang Xiaoqi Yu; Serious diseases,particularly cancer,consistently pose significant threats to both national health and economic development[1].The cancer diagnosis methods such as fluorescent probes[2,3],as well as treatment techniqu...; 关键词：DIAGNOSIS DRUGS TREATMENT FORUM

CAR-T cells for cancer immunotherapy被引量：2: 《Chinese Chemical Letters》2023年第9期55-64,共10页Yangyang Xie Xiaotong Li Jingyi Wu Huiling Zeng Hamza Boucetta Binru Wang Pei Yang Wei He; supported by the National Natural Science Foundation of China(Nos.81872823,82073782 and 82241002);the Shanghai Science and Technology Committee(No.19430741500);National Innovation and Entrepreneurship Training Program for Undergraduate(No.202210316145);the Key Laboratory of Modern Chinese Medicine Preparation of Ministry of Education of Jiangxi University of Traditional Chinese Medicine(No.zdsys202103)。; Adoptive immunotherapy expressing synthetic chimeric antigen receptors(CAR)on T cells through in vitro modifications represents a new and innovative strategy in cancer treatment.This new approach enables T cells to re...; 关键词：CAR-T cells Cancer Immunotherapy Therapeutic techniques Marketed drugs Universal CAR-T Cell Therapy

Oral delivery of polyester nanoparticles for brain-targeting: Challenges and opportunities被引量：1: 《Chinese Chemical Letters》2023年第4期99-109,共11页Ping Wang Yue Wang Ping Li Chen Chen Siman Ma Linxuan Zhao Haibing He Tian Yin Yu Zhang Xing Tang Jingxin Gou; supported by the National Key R&D Program of China (No. 2020YFE0201700);the National Mega-project for Innovative Drugs (No. 2019ZX09721001);the National Natural Science Foundation of China (No. 81673378);the Liaoning Revitalization Talents Program (No. XLYC1908031);the Project of Liaoning Provincial Department of Education (No. 2019LQN07);the PhD Research Startup Foundation of Liaoning Province (No. 2020-BS-128)。; Efficient oral delivery of drugs treating brain diseases has long been a challenging topic faced by the drug delivery community. Fortunately, polyester nanoparticles offer certain solutions to this problem. This revie...; 关键词：Polyester nanoparticles Oral brain drugs Brain-targeted delivery Physiological barrier Absorption enhancement

Fluorine-containing drugs approved by the FDA in 2021: 《Chinese Chemical Letters》2023年第1期29-38,共10页Jingrui He Ziyi Li Gagan Dhawan Wei Zhang Alexander E.Sorochinsky Greg Butler Vadim A.Soloshonok Jianlin Han; the financial support from the National Natural Science Foundation of China(No.21761132021);the Qing-Lan Project of Jiangsu Province(for Han);IKERBASQUE,Basque Foundation for Science(for Soloshonok)。; Nine new fluorine-containing drugs have been approved by the US Food and Drug Administration(FDA)in 2021,which are presented in this review article.These small molecular drugs feature aromatic fluorine,trifluoromethyl...; 关键词：Fluorine-containing compounds Blockbuster drugs Pharmaceuticals ANTI-CANCER Drug design and development Asymmetric synthesis

Fluorine-containing pharmaceuticals approved by the FDA in 2020:Synthesis and biological activity被引量：1: 《Chinese Chemical Letters》2021年第11期3342-3354,共13页Yingjie Yu Aiyao Liu Gagan Dhawan Haibo Mei Wei Zhang Kunisuke Izawa Vadim A.Soloshonok Jianlin Han; the financial support from the National Natural Science Foundation of China(No.21761132021);IKERBASQUE,Basque Foundation for Science.; Thirteen new fluorine-containing drugs,which have been granted approval by the US Food and Drug Administration(FDA)in 2020,are profiled in this review.Therapeutic areas of these new fluorinated pharmaceuticals include...; 关键词：Fluorine and compounds Blockbuster drugs Modern pharmaceuticals SYNTHESIS Drug design and development Asymmetric synthesis

Fluorine-containing drugs approved by the FDA in 2019被引量：2: 《Chinese Chemical Letters》2020年第9期2401-2413,共13页Haibo Mei Attila Mario Remete Yupiao Zou Hiroki Moriwaki Santos Fustero Lorand Kiss Vadim ASoloshonok Jianlin Han; financial support from the financial support from the National Natural Science Foundation of China(No.21761132021);IKERBASQUE,Basque Foundation for Science;The Hungarian Research Foundation(NKFIH No.K119282);Ministry of Human Capacities,Hungary grant 20391-3/2018/FEKUSTRAT。; Eleven new fluorine-containing FDA-approved drugs have been profiled and details of their discovery and preparation are discussed.Therapeutic areas include schizophrenia,migraine,multiple sclerosis,insomnia,rheumatoid...; 关键词：FLUORINE Pharmaceuticals SYNTHESIS Medicinal chemistry Marketed medicinal drugs

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

DRUGS

检索结果分析

下载全文

高级检索检索式检索

时间限定

期刊范围

学科限定全选

高级检索 检索式检索

时间限定

期刊范围

学科限定全选

DRUGS

检索结果分析

下载全文

用户登录

高级检索检索式检索